Cytosolic aspartate availability determines cell survival when glutamine is limiting HF Alkan, KE Walter, A Luengo, CT Madreiter-Sokolowski, S Stryeck, ... Cell metabolism 28 (5), 706-720. e6, 2018 | 180 | 2018 |
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, ... Nature 605 (7911), 747-753, 2022 | 159 | 2022 |
Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet S Karaman, M Hollmén, MR Robciuc, A Alitalo, H Nurmi, B Morf, ... Molecular metabolism 4 (2), 93-105, 2015 | 127 | 2015 |
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling P Altea-Manzano, G Doglioni, Y Liu, AM Cuadros, E Nolan, ... Nature cancer 4 (3), 344-364, 2023 | 85 | 2023 |
Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice S Karaman, M Hollmén, SY Yoon, HF Alkan, K Alitalo, C Wolfrum, ... Scientific reports 6 (1), 31566, 2016 | 53 | 2016 |
Maintaining cytosolic aspartate levels is a major function of the TCA cycle in proliferating cells HF Alkan, JG Bogner-Strauss Molecular & Cellular Oncology 6 (5), e1536843, 2019 | 34 | 2019 |
Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis HF Alkan, PW Vesely, H Hackl, J Foßelteder, DR Schmidt, ... Cancer & Metabolism 8, 1-13, 2020 | 17 | 2020 |
Co-chaperone bag-1 plays a role in the autophagy-dependent cell survival through Beclin 1 interaction M Turk, O Tatli, HF Alkan, P Ozfiliz Kilbas, G Alkurt, G Dinler Doganay Molecules 26 (4), 854, 2021 | 15 | 2021 |
HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation AA Urrutia, C Mesa-Ciller, A Guajardo-Grence, HF Alkan, I Soro-Arnáiz, ... Cell Reports 43 (4), 2024 | 6 | 2024 |
Palmitic acid: Enabling the tumor’s nerves HF Alkan, P Altea-Manzano, SM Fendt Cell Metabolism 34 (1), 7-9, 2022 | 6 | 2022 |
N-acetylaspartate improves cell survival when glucose is limiting HF Alkan, KE Walter, H Hackl, MG Vander Heiden, T Madl, ... bioRxiv, 2020.05. 28.114629, 2020 | 4 | 2020 |
Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet. Mol Metab. 2014; 4 (2): 93-105 S Karaman, M Hollmén, MR Robciuc, A Alitalo, H Nurmi, B Morf, ... | 3 | |
Aspartate signalling drives lung metastasis via alternative translation G Doglioni, J Fernández-García, S Igelmann, P Altea-Manzano, ... Nature, 1-7, 2025 | 1 | 2025 |
The primary tumor secretome alters the metabolism of the pre-metastatic niche and promotes metastasis. G Doglioni, P Altea-Manzano, J Fernandez-Garcia, I Vermiere, M Planque, ... EACR Cancer Metabolism, Location: Bilbao, 2022 | | 2022 |
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis (vol 605. pg 747, 2022) M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, ... NATURE 609 (7927), E8-E8, 2022 | | 2022 |
Loss of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis HF Alkan, PW Vesely, H Hackl, J Foßelteder, MG Vander Heiden, ... bioRxiv, 2020.05. 29.121400, 2020 | | 2020 |
Pex16 is a required factor for white adipocyte lipid and energy homeostasis D Hofer, A Pessentheiner, HJ Pelzmann, K Huber, HF Alkan, ... Peroxisystem 2016, 2016 | | 2016 |
Characterization of N-acetyltransferase 8-like (NAT8L)-knockout mice with regard to lipid and energy homeostasis D Hofer, HJ Pelzmann, K Huber, HF Alkan, A Pessentheiner, ... Doctoral Day of the Medical University of Graz, 2016 | | 2016 |
Pex16 is a required factor for adipocyte lipid and energy homeostasis D Hofer, A Pessentheiner, HJ Pelzmann, K Huber, HF Alkan, ... 5th DK-MCD Scientific Retreat, 2015 | | 2015 |
N-acetyltransferase 8-like (Nat8l), regulates cellular acetyl-CoA levels in brown adipocytes: Impact on energy metabolism and autophagy K Huber, A Pessentheiner, HJ Pelzmann, D Hofer, K Dagmar, C Magnes, ... 5th DK-MCD Scientific Retreat, 2015 | | 2015 |