Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ... Nature immunology 11 (10), 897-904, 2010 | 1471 | 2010 |
T-box transcription factors combine with the cytokines TGF-β and IL-15 to control tissue-resident memory T cell fate LK Mackay, E Wynne-Jones, D Freestone, DG Pellicci, LA Mielke, ... Immunity 43 (6), 1101-1111, 2015 | 612 | 2015 |
The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells A Vasanthakumar, K Moro, A Xin, Y Liao, R Gloury, S Kawamoto, ... Nature immunology 16 (3), 276-285, 2015 | 591 | 2015 |
IL‐17‐producing γδ T cells and innate lymphoid cells CE Sutton, LA Mielke, KHG Mills European journal of immunology 42 (9), 2221-2231, 2012 | 351 | 2012 |
Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation LA Mielke, SA Jones, M Raverdeau, R Higgs, A Stefanska, JR Groom, ... Journal of Experimental Medicine 210 (6), 1117-1124, 2013 | 342 | 2013 |
The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway LC Rankin, JR Groom, M Chopin, MJ Herold, JA Walker, LA Mielke, ... Nature immunology 14 (4), 389-395, 2013 | 308 | 2013 |
General nature of the STAT3-activated anti-inflammatory response KC El Kasmi, J Holst, M Coffre, L Mielke, A De Pauw, N Lhocine, ... The Journal of Immunology 177 (11), 7880-7888, 2006 | 267 | 2006 |
Complementarity and redundancy of IL-22-producing innate lymphoid cells LC Rankin, MJH Girard-Madoux, C Seillet, LA Mielke, Y Kerdiles, A Fenis, ... Nature immunology 17 (2), 179-186, 2016 | 256 | 2016 |
Nfil3 is required for the development of all innate lymphoid cell subsets C Seillet, LC Rankin, JR Groom, LA Mielke, J Tellier, M Chopin, ... Journal of Experimental Medicine 211 (9), 1733-1740, 2014 | 253 | 2014 |
The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability JJ Babon, EJ McManus, S Yao, DP DeSouza, LA Mielke, NS Sprigg, ... Molecular cell 22 (2), 205-216, 2006 | 203 | 2006 |
Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells P Sathe, RB Delconte, F Souza-Fonseca-Guimaraes, C Seillet, M Chopin, ... Nature communications 5 (1), 4539, 2014 | 183 | 2014 |
The comparative roles of suppressor of cytokine signaling-1 and-3 in the inhibition and desensitization of cytokine signaling S Wormald, JG Zhang, DL Krebs, LA Mielke, J Silver, WS Alexander, ... Journal of Biological Chemistry 281 (16), 11135-11143, 2006 | 169 | 2006 |
Deciphering the innate lymphoid cell transcriptional program C Seillet, LA Mielke, DB Amann-Zalcenstein, S Su, J Gao, FF Almeida, ... Cell reports 17 (2), 436-447, 2016 | 152 | 2016 |
TCF-1 controls ILC2 and NKp46+ RORγt+ innate lymphocyte differentiation and protection in intestinal inflammation LA Mielke, JR Groom, LC Rankin, C Seillet, F Masson, T Putoczki, ... The Journal of Immunology 191 (8), 4383-4391, 2013 | 150 | 2013 |
The TNF receptor superfamily-NF-κB axis is critical to maintain effector regulatory T cells in lymphoid and non-lymphoid tissues A Vasanthakumar, Y Liao, P Teh, MF Pascutti, AE Oja, AL Garnham, ... Cell reports 20 (12), 2906-2920, 2017 | 142 | 2017 |
The helix-loop-helix protein ID2 governs NK cell fate by tuning their sensitivity to interleukin-15 RB Delconte, W Shi, P Sathe, T Ushiki, C Seillet, M Minnich, TB Kolesnik, ... Immunity 44 (1), 103-115, 2016 | 129 | 2016 |
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia BT Kile, AD Panopoulos, RA Stirzaker, DF Hacking, LH Tahtamouni, ... Blood, The Journal of the American Society of Hematology 110 (7), 2371-2380, 2007 | 125 | 2007 |
Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1β production LA Mielke, KL Elkins, L Wei, R Starr, PN Tsichlis, JJ O'Shea, WT Watford The Journal of Immunology 183 (12), 7984-7993, 2009 | 121 | 2009 |
NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease H Tye, CH Yu, LA Simms, MR de Zoete, ML Kim, M Zakrzewski, ... Nature communications 9 (1), 3728, 2018 | 120 | 2018 |
Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii WT Watford, BD Hissong, LR Durant, H Yamane, LM Muul, Y Kanno, ... The Journal of experimental medicine 205 (12), 2803-2812, 2008 | 107 | 2008 |