Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ... Nature immunology 11 (10), 897-904, 2010 | 1470 | 2010 |
Local structural elements in the mostly unstructured transcriptional activation domain of human p53 H Lee, KH Mok, R Muhandiram, KH Park, JE Suk, DH Kim, J Chang, ... Journal of Biological Chemistry 275 (38), 29426-29432, 2000 | 392 | 2000 |
A pre-existing hydrophobic collapse in the unfolded state of an ultrafast folding protein KH Mok, LT Kuhn, M Goez, IJ Day, JC Lin, NH Andersen, PJ Hore Nature 447 (7140), 106-109, 2007 | 202 | 2007 |
Photo-CIDNP NMR methods for studying protein folding KH Mok, PJ Hore Methods 34 (1), 75-87, 2004 | 128 | 2004 |
Rapid sample-mixing technique for transient NMR and photo-CIDNP spectroscopy: applications to real-time protein folding KH Mok, T Nagashima, IJ Day, JA Jones, CJV Jones, CM Dobson, ... Journal of the American Chemical Society 125 (41), 12484-12492, 2003 | 125 | 2003 |
Structure and function of human α‐lactalbumin made lethal to tumor cells (HAMLET)‐type complexes AK Mossberg, K Hun Mok, LA Morozova‐Roche, C Svanborg The FEBS journal 277 (22), 4614-4625, 2010 | 105 | 2010 |
HAMLET, protein folding, and tumor cell death KH Mok, J Pettersson, S Orrenius, C Svanborg Biochemical and biophysical research communications 354 (1), 1-7, 2007 | 99 | 2007 |
α-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding J Pettersson-Kastberg, AK Mossberg, M Trulsson, YJ Yong, S Min, Y Lim, ... Journal of molecular biology 394 (5), 994-1010, 2009 | 95 | 2009 |
Multiple subsets of side-chain packing in partially folded states of α-lactalbumins KH Mok, T Nagashima, IJ Day, PJ Hore, CM Dobson Proceedings of the National Academy of Sciences 102 (25), 8899-8904, 2005 | 90 | 2005 |
Protein oligomerization induced by oleic acid at the solid–liquid interface–equine lysozyme cytotoxic complexes K Wilhelm, A Darinskas, W Noppe, E Duchardt, KH Mok, V Vukojević, ... The FEBS Journal 276 (15), 3975-3989, 2009 | 72 | 2009 |
Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion AF McGettrick, SE Corcoran, PJG Barry, J McFarland, C Crès, AM Curtis, ... Proceedings of the National Academy of Sciences 113 (48), E7778-E7787, 2016 | 63 | 2016 |
Cytotoxic complexes of sodium oleate with β‐lactoglobulin K Lišková, MAE Auty, V Chaurin, S Min, KH Mok, N O'Brien, AL Kelly, ... European Journal of Lipid Science and Technology 113 (10), 1207-1218, 2011 | 60 | 2011 |
Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1α–Dependent inflammation GA Tynan, CH Hearnden, E Oleszycka, CL Lyons, G Coutts, J O’Connell, ... Diabetes 63 (6), 2037-2050, 2014 | 52 | 2014 |
Temperature and urea induced denaturation of the TRP‐cage mini protein TC5b: A simulation study consistent with experimental observations Z Gattin, S Riniker, PJ Hore, KH Mok, WF van Gunsteren Protein Science 18 (10), 2090-2099, 2009 | 47 | 2009 |
Can misfolded proteins be beneficial? The HAMLET case J Pettersson-Kastberg, S Aits, L Gustafsson, A Mossberg, P Storm, ... Annals of medicine 41 (3), 162-176, 2009 | 47 | 2009 |
Nuclear magnetic resonance solution conformation of α-conotoxin AuIB, an α3β4 subtype-selective neuronal nicotinic acetylcholine receptor antagonist JH Cho, KH Mok, BM Olivera, JM McIntosh, KH Park, KH Han Journal of Biological Chemistry 275 (12), 8680-8685, 2000 | 47 | 2000 |
Sperm-coating beta-defensin 126 is a dissociation-resistant dimer produced by epididymal epithelium in the bovine reproductive tract F Narciandi, B Fernandez-Fuertes, I Khairulzaman, H Jahns, D King, ... Biology of Reproduction 95 (6), 121, 1-9, 2016 | 38 | 2016 |
Photo-CIDNP experiments with an optimized presaturation pulse train, gated continuous illumination, and a background-nulling pulse grid M Goez, KH Mok, PJ Hore Journal of Magnetic Resonance 177 (2), 236-246, 2005 | 36 | 2005 |
Amyloid oligomers and mature fibrils prepared from an innocuous protein cause diverging cellular death mechanisms NP Harte, I Klyubin, EK McCarthy, S Min, SA Garrahy, Y Xie, GP Davey, ... Journal of Biological Chemistry 290 (47), 28343-28352, 2015 | 35 | 2015 |
Synthesis, characterization, in vitro antimicrobial, and U2OS tumoricidal activities of different coumarin derivatives S Rehman, M Ikram, RJ Baker, M Zubair, E Azad, S Min, K Riaz, KH Mok, ... BMC Chemistry 7, 1-12, 2013 | 35 | 2013 |