Seuraa
Umesh Jinwal
Umesh Jinwal
University of South Florida, Byrd Alzheimer’s Institute, College of Pharmacy
Vahvistettu sähköpostiosoite verkkotunnuksessa health.usf.edu
Nimike
Viittaukset
Viittaukset
Vuosi
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
114402021
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation
JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ...
The Journal of Neuroscience 33 (22), 9498-9507, 2013
2792013
Chemical manipulation of hsp70 ATPase activity regulates tau stability
UK Jinwal, Y Miyata, J Koren, JR Jones, JH Trotter, L Chang, J O'Leary, ...
Journal of neuroscience 29 (39), 12079-12088, 2009
2792009
Akt and CHIP coregulate tau degradation through coordinated interactions
CA Dickey, J Koren, YJ Zhang, Y Xu, UK Jinwal, MJ Birnbaum, B Monks, ...
Proceedings of the National Academy of Sciences 105 (9), 3622-3627, 2008
2542008
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules
UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ...
The Journal of Neuroscience 30 (2), 591-599, 2010
2442010
Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones
A Rousaki, Y Miyata, UK Jinwal, CA Dickey, JE Gestwicki, ERP Zuiderweg
Journal of molecular biology 411 (3), 614-632, 2011
2142011
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ...
Molecular neurodegeneration 5, 1-11, 2010
2122010
Chaperone signalling complexes in Alzheimer's disease
J Koren III, UK Jinwal, DC Lee, JR Jones, CL Shults, AG Johnson, ...
Journal of cellular and molecular medicine 13 (4), 619-630, 2009
1552009
Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice
L Lebson, K Nash, S Kamath, D Herber, N Carty, DC Lee, Q Li, ...
The Journal of Neuroscience 30 (29), 9651-9658, 2010
1502010
1, 25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498
R Kasiappan, Z Shen, KW Anfernee, U Jinwal, J Tang, P Lungchukiet, ...
Journal of Biological Chemistry 287 (49), 41297-41309, 2012
1492012
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51
JC O'Leary III, S Dharia, LJ Blair, S Brady, AG Johnson, M Peters, ...
PloS one 6 (9), e24840, 2011
1442011
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice
JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ...
The Journal of Neuroscience 30 (46), 15374-15382, 2010
1422010
Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels
Y Miyata, X Li, HF Lee, UK Jinwal, SR Srinivasan, SP Seguin, ZT Young, ...
ACS chemical neuroscience 4 (6), 930-939, 2013
1412013
Natural products as a rich source of tau-targeting drugs for Alzheimer’s disease
L Calcul, B Zhang, UK Jinwal, CA Dickey, BJ Baker
Future medicinal chemistry 4 (13), 1751-1761, 2012
1362012
Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome
JL Daily, K Nash, U Jinwal, T Golde, J Rogers, MM Peters, RD Burdine, ...
PloS one 6 (12), e27221, 2011
1352011
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau
J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ...
Biological psychiatry 74 (5), 367-374, 2013
1332013
Imbalance of Hsp70 family variants fosters tau accumulation
UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ...
The FASEB Journal 27 (4), 1450, 2013
1312013
Hsc70 rapidly engages tau after microtubule destabilization
UK Jinwal, JC O'Leary, SI Borysov, JR Jones, Q Li, J Koren, JF Abisambra, ...
Journal of biological chemistry 285 (22), 16798-16805, 2010
1072010
Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70
Y Miyata, JN Rauch, UK Jinwal, AD Thompson, S Srinivasan, CA Dickey, ...
Chemistry & biology 19 (11), 1391-1399, 2012
1012012
Facilitating Akt clearance via manipulation of Hsp70 activity and levels
J Koren, UK Jinwal, Y Jin, J O’Leary, JR Jones, AG Johnson, LJ Blair, ...
Journal of biological chemistry 285 (4), 2498-2505, 2010
1002010
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Artikkelit 1–20