| An overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals KS Gates Chemical research in toxicology 22 (11), 1747-1760, 2009 | 598 | 2009 |
| Biologically relevant chemical reactions of N7-alkylguanine residues in DNA KS Gates, T Nooner, S Dutta Chemical research in toxicology 17 (7), 839-856, 2004 | 297 | 2004 |
| Redox regulation of protein tyrosine phosphatases: structural and chemical aspects JJ Tanner, ZD Parsons, AH Cummings, H Zhou, KS Gates Antioxidants & redox signaling 15 (1), 77-97, 2011 | 201 | 2011 |
| Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1, 4-di-N-oxide B Ganley, G Chowdhury, J Bhansali, JS Daniels, KS Gates Bioorganic & medicinal chemistry 9 (9), 2395-2401, 2001 | 185 | 2001 |
| DNA damage by fasicularin S Dutta, H Abe, S Aoyagi, C Kibayashi, KS Gates Journal of the American Chemical Society 127 (43), 15004-15005, 2005 | 181 | 2005 |
| DNA cleavage by the antitumor agent 3-amino-1, 2, 4-benzotriazine 1, 4-dioxide (SR4233): evidence for involvement of hydroxyl radical JS Daniels, KS Gates Journal of the American Chemical Society 118 (14), 3380-3385, 1996 | 176 | 1996 |
| Interstrand cross-links generated by abasic sites in duplex DNA S Dutta, G Chowdhury, KS Gates Journal of the American Chemical Society 129 (7), 1852-1853, 2007 | 161 | 2007 |
| Interstrand DNA–DNA cross-link formation between adenine residues and abasic sites in duplex DNA NE Price, KM Johnson, J Wang, MI Fekry, Y Wang, KS Gates Journal of the American Chemical Society 136 (9), 3483-3490, 2014 | 149 | 2014 |
| DNA base damage by the antitumor agent 3-amino-1, 2, 4-benzotriazine 1, 4-dioxide (tirapazamine) M Birincioglu, P Jaruga, G Chowdhury, H Rodriguez, M Dizdaroglu, ... Journal of the American Chemical Society 125 (38), 11607-11615, 2003 | 116 | 2003 |
| Oxidative DNA cleavage by the antitumor antibiotic leinamycin and simple 1, 2-dithiolan-3-one 1-oxides: Evidence for thiol-dependent conversion of molecular oxygen to DNA … K Mitra, W Kim, JS Daniels, KS Gates Journal of the American Chemical Society 119 (48), 11691-11692, 1997 | 105 | 1997 |
| On the formation and properties of interstrand DNA–DNA cross-links forged by reaction of an abasic site with the opposing guanine residue of 5′-CAp sequences in duplex DNA KM Johnson, NE Price, J Wang, MI Fekry, S Dutta, DR Seiner, Y Wang, ... Journal of the American Chemical Society 135 (3), 1015-1025, 2013 | 102 | 2013 |
| Direct evidence for bimodal DNA damage induced by tirapazamine JS Daniels, KS Gates, C Tronche, MM Greenberg Chemical research in toxicology 11 (11), 1254-1257, 1998 | 99 | 1998 |
| Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein DR Seiner, JN LaButti, KS Gates Chemical research in toxicology 20 (9), 1315-1320, 2007 | 92 | 2007 |
| Mechanisms of DNA damage by leinamycin KS Gates Chemical Research in Toxicology 13 (10), 953-956, 2000 | 91 | 2000 |
| Generation of reactive oxygen species by a persulfide (BnSSH) T Chatterji, K Keerthi, KS Gates Bioorganic & medicinal chemistry letters 15 (17), 3921-3924, 2005 | 89 | 2005 |
| A chemical model for redox regulation of protein tyrosine phosphatase 1B (PTP1B) activity S Sivaramakrishnan, K Keerthi, KS Gates Journal of the American Chemical Society 127 (31), 10830-10831, 2005 | 89 | 2005 |
| Synthesis and Biological Evaluation of New 2-Arylcarbonyl-3-trifluoromethylquinoxaline 1,4-Di-N-oxide Derivatives and Their Reduced Analogues B Solano, V Junnotula, A Marín, R Villar, A Burguete, E Vicente, ... Journal of medicinal chemistry 50 (22), 5485-5492, 2007 | 87 | 2007 |
| DNA binding and alkylation by the “left half” of azinomycin B H Zang, KS Gates Biochemistry 39 (48), 14968-14975, 2000 | 86 | 2000 |
| 3-Amino-1, 2, 4-benzotriazine 4-oxide: characterization of a new metabolite arising from bioreductive processing of the antitumor agent 3-amino-1, 2, 4-benzotriazine 1, 4 … T Fuchs, G Chowdhury, CL Barnes, KS Gates The Journal of organic chemistry 66 (1), 107-114, 2001 | 84 | 2001 |
| Reaction of the hypoxia-selective antitumor agent tirapazamine with a C1 ‘-radical in single-stranded and double-stranded DNA: The drug and its metabolites can serve as … JT Hwang, MM Greenberg, T Fuchs, KS Gates Biochemistry 38 (43), 14248-14255, 1999 | 83 | 1999 |
