NMR spectroscopy reveals that RNase A is chiefly denatured in 40% acetic acid: implications for oligomer formation by 3D domain swapping JP Lopez-Alonso, M Bruix, J Font, M Ribo, M Vilanova, MA Jimenez, ... Journal of the American Chemical Society 132 (5), 1621-1630, 2010 | 71 | 2010 |
Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome A Schedlbauer, T Kaminishi, B Ochoa-Lizarralde, N Dhimole, S Zhou, ... Antimicrobial agents and chemotherapy 59 (5), 2849-2854, 2015 | 55 | 2015 |
Carbodiimide EDC induces cross-links that stabilize RNase A C-dimer against dissociation: EDC adducts can affect protein net charge, conformation, and activity JP López-Alonso, F Diez-Garcia, J Font, M Ribó, M Vilanova, JM Scholtz, ... Bioconjugate chemistry 20 (8), 1459-1473, 2009 | 52 | 2009 |
Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways JP Lopez-Alonso, A Fabbretti, T Kaminishi, I Iturrioz, L Brandi, ... Nucleic acids research 45 (4), 2179-2187, 2017 | 41 | 2017 |
Proliferating cell nuclear antigen (PCNA) interactions in solution studied by NMR A De Biasio, R Campos-Olivas, R Sánchez, JP López-Alonso, ... PloS one 7 (11), e48390, 2012 | 40 | 2012 |
A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit A Schedlbauer, I Iturrioz, B Ochoa-Lizarralde, T Diercks, JP López-Alonso, ... Science Advances 7 (23), eabf7547, 2021 | 39* | 2021 |
Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer*. JP López-Alonso, M Bruix, J Font, M Ribó, M Vilanova, M Rico, G Gotte, ... Journal of Biological Chemistry 281 (14), 9400-9406, 2006 | 32 | 2006 |
RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket JP López-Alonso, T Kaminishi, T Kikuchi, Y Hirata, I Iturrioz, N Dhimole, ... Nucleic Acids Research 45 (11), 6945-6959, 2017 | 30 | 2017 |
Salt anions promote the conversion of HypF-N into amyloid-like oligomers and modulate the structure of the oligomers and the monomeric precursor state S Campioni, B Mannini, JP López-Alonso, IN Shalova, A Penco, ... Journal of Molecular Biology 424 (3-4), 132-149, 2012 | 29 | 2012 |
Construction, purification and characterization of untagged human liver alanine-glyoxylate aminotransferase expressed in Escherichia coli CB Voltattorni, B Cellini, R Montioli, S Bianconi, JP Lopez-Alonso Protein and peptide letters 15 (2), 153-159, 2008 | 27 | 2008 |
Crowding agents and osmolytes provide insight into the formation and dissociation of RNase A oligomers C Ercole, JP López-Alonso, J Font, M Ribó, M Vilanova, D Picone, ... Archives of Biochemistry and Biophysics 506 (2), 123-129, 2011 | 25 | 2011 |
Kinetic analysis provides insight into the mechanism of ribonuclease A oligomer formation JP López-Alonso, G Gotte, DV Laurents Archives of biochemistry and biophysics 489 (1-2), 41-47, 2009 | 20 | 2009 |
CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase JP López-Alonso, M Lázaro, D Gil-Cartón, PH Choi, A Dodu, L Tong, ... Nature communications 13 (1), 6185, 2022 | 18 | 2022 |
Phosphorylation-dependent changes in nucleotide binding, conformation, and dynamics of the first nucleotide binding domain (NBD1) of the sulfonylurea receptor 2B (SUR2B) ED de Araujo, CP Alvarez, JP Lopez-Alonso, CR Sooklal, M Stagljar, ... Journal of Biological Chemistry 290 (37), 22699-22714, 2015 | 17 | 2015 |
Phosphorylation alters the residual structure and interactions of the regulatory L1 linker connecting NBD1 to the membrane-bound domain in SUR2B CR Sooklal, JP Lopez-Alonso, N Papp, V Kanelis Biochemistry 57 (44), 6278-6292, 2018 | 12 | 2018 |
NMR and fluorescence studies of drug binding to the first nucleotide binding domain of SUR2A JP López-Alonso, ED de Araujo, V Kanelis Biochemistry 51 (45), 9211-9222, 2012 | 12 | 2012 |
Putative One‐Pot Prebiotic Polypeptides with Ribonucleolytic Activity JP López‐Alonso, MA Pardo‐Cea, I Gómez‐Pinto, I Fernández, ... Chemistry–A European Journal 16 (18), 5314-5323, 2010 | 11 | 2010 |
3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme M Lázaro, R Melero, C Huet, JP López-Alonso, S Delgado, A Dodu, ... Communications Biology 4 (1), 684, 2021 | 7 | 2021 |
Preparation of ribonuclease S domain-swapped dimers conjugated with DNA and PNA: Modulating the activity of ribonucleases D Pulido, JP López-Alonso, V Marchán, C González, A Grandas, ... Bioconjugate chemistry 19 (1), 263-270, 2008 | 7 | 2008 |
Structural basis for regulation of a CBASS-CRISPR-Cas defense island by a transmembrane anti-σ factor and its ECF σ partner D Bernal-Bernal, D Pantoja-Uceda, JP López-Alonso, A López-Rojo, ... Science advances 10 (43), eadp1053, 2024 | 1 | 2024 |