| Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism F Cabreiro, C Au, KY Leung, N Vergara-Irigaray, HM Cochemé, T Noori, ... Cell 153 (1), 228-239, 2013 | 1057 | 2013 |
| Complex I is the major site of mitochondrial superoxide production by paraquat HM Cochemé, MP Murphy Journal of biological chemistry 283 (4), 1786-1798, 2008 | 699 | 2008 |
| Redox metabolism: ROS as specific molecular regulators of cell signaling and function C Lennicke, HM Cochemé Molecular cell 81 (18), 3691-3707, 2021 | 688 | 2021 |
| Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ... Nature medicine 19 (6), 753-759, 2013 | 682 | 2013 |
| Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology MF Ross, GF Kelso, FH Blaikie, AM James, HM Cocheme, A Filipovska, ... Biochemistry (Moscow) 70, 222-230, 2005 | 584 | 2005 |
| Mitochondrial pharmacology RAJ Smith, RC Hartley, HM Cocheme, MP Murphy Trends in pharmacological sciences 33 (6), 341-352, 2012 | 572 | 2012 |
| Interactions of Mitochondria-targeted and Untargeted Ubiquinones with the Mitochondrial Respiratory Chain and Reactive Oxygen Species: IMPLICATIONS FOR THE USE OF EXOGENOUS … AM James, HM Cochemé, RAJ Smith, MP Murphy Journal of Biological Chemistry 280 (22), 21295-21312, 2005 | 472 | 2005 |
| Mitochondria-Targeted Antioxidant MitoQ10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy D Graham, NN Huynh, CA Hamilton, E Beattie, RAJ Smith, HM Cochemé, ... Hypertension 54 (2), 322-328, 2009 | 414 | 2009 |
| Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from … MP Murphy, KS Echtay, FH Blaikie, J Asin-Cayuela, HM Cochemé, ... Journal of Biological Chemistry 278 (49), 48534-48545, 2003 | 373 | 2003 |
| Mitochondrial redox signalling at a glance Y Collins, ET Chouchani, AM James, KE Menger, HM Cochemé, ... Journal of cell science 125 (4), 801-806, 2012 | 337 | 2012 |
| Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix HM Cochemé, C Quin, SJ McQuaker, F Cabreiro, A Logan, TA Prime, ... Cell metabolism 13 (3), 340-350, 2011 | 336 | 2011 |
| Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice S Rodriguez-Cuenca, HM Cochemé, A Logan, I Abakumova, TA Prime, ... Free Radical Biology and Medicine 48 (1), 161-172, 2010 | 244 | 2010 |
| Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ... Cell 178 (6), 1299-1312. e29, 2019 | 233 | 2019 |
| Oxidative stress and life histories: unresolved issues and current needs JR Speakman, JD Blount, AM Bronikowski, R Buffenstein, C Isaksson, ... Ecology and Evolution 5 (24), 5745-5757, 2015 | 214 | 2015 |
| Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ... Brain 138 (7), 1801-1816, 2015 | 206 | 2015 |
| Mitochondrial targeting of quinones: therapeutic implications HM Cochemé, GF Kelso, AM James, MF Ross, J Trnka, T Mahendiran, ... Mitochondrion 7, S94-S102, 2007 | 170 | 2007 |
| Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat EL Robb, JM Gawel, D Aksentijević, HM Cochemé, TS Stewart, ... Free Radical Biology and Medicine 89, 883-894, 2015 | 149 | 2015 |
| Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling N Alic, TD Andrews, ME Giannakou, I Papatheodorou, C Slack, ... Molecular systems biology 7 (1), 502, 2011 | 147 | 2011 |
| Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease F Kerr, O Sofola-Adesakin, DK Ivanov, J Gatliff, B Gomez Perez-Nievas, ... PLoS genetics 13 (3), e1006593, 2017 | 145 | 2017 |
| Mitochondria‐targeted antioxidants in the treatment of disease RAJ Smith, VJ Adlam, FH Blaikie, ARB Manas, CM Porteous, AM James, ... Annals of the New York Academy of Sciences 1147 (1), 105-111, 2008 | 139 | 2008 |