| Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119-124, 2012 | 5372 | 2012 |
| Microbial exposure during early life has persistent effects on natural killer T cell function T Olszak, D An, S Zeissig, MP Vera, J Richter, A Franke, JN Glickman, ... Science 336 (6080), 489-493, 2012 | 1896 | 2012 |
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease A Kaser, AH Lee, A Franke, JN Glickman, S Zeissig, H Tilg, ... Cell 134 (5), 743-756, 2008 | 1624 | 2008 |
| Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease S Zeissig, N Bürgel, D Günzel, J Richter, J Mankertz, U Wahnschaffe, ... Gut 56 (1), 61-72, 2007 | 1451 | 2007 |
| Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig, T Ahmad, ... The Lancet 387 (10014), 156-167, 2016 | 877 | 2016 |
| Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4 Y Junker, S Zeissig, SJ Kim, D Barisani, H Wieser, DA Leffler, V Zevallos, ... Journal of Experimental Medicine 209 (13), 2395-2408, 2012 | 770 | 2012 |
| International IBD Genetics Consortium (IIBDGC). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119-124, 2012 | 642 | 2012 |
| Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells D An, SF Oh, T Olszak, JF Neves, FY Avci, D Erturk-Hasdemir, X Lu, ... Cell 156 (1), 123-133, 2014 | 611 | 2014 |
| A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis S Buch, F Stickel, E Trépo, M Way, A Herrmann, HD Nischalke, M Brosch, ... Nature genetics 47 (12), 1443-1448, 2015 | 592 | 2015 |
| Epithelial tight junctions in intestinal inflammation JD Schulzke, S Ploeger, M Amasheh, A Fromm, S Zeissig, H Troeger, ... Annals of the New York Academy of Sciences 1165 (1), 294-300, 2009 | 476 | 2009 |
| Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects C Schwab, A Gabrysch, P Olbrich, V Patiño, K Warnatz, D Wolff, ... Journal of Allergy and Clinical Immunology 142 (6), 1932-1946, 2018 | 412 | 2018 |
| Downregulation of epithelial apoptosis and barrier repair in active Crohn’s disease by tumour necrosis factor α antibody treatment S Zeissig, C Bojarski, N Buergel, J Mankertz, M Zeitz, M Fromm, ... Gut 53 (9), 1295-1302, 2004 | 382 | 2004 |
| High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ... Nature genetics 47 (2), 172-179, 2015 | 354 | 2015 |
| Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104: H4 induced haemolytic uraemic syndrome: case-control study J Menne, M Nitschke, R Stingele, M Abu-Tair, J Beneke, J Bramstedt, ... Bmj 345, 2012 | 348 | 2012 |
| Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease S Zeissig, RS Blumberg Nature immunology 15 (4), 307-310, 2014 | 277 | 2014 |
| Hepatitis B virus–induced lipid alterations contribute to natural killer T cell–dependent protective immunity S Zeissig, K Murata, L Sweet, J Publicover, Z Hu, A Kaser, E Bosse, ... Nature medicine 18 (7), 1060-1068, 2012 | 272 | 2012 |
| Disrupted barrier function through epithelial cell apoptosis JD SCHULZKE, C Bojarski, S Zeissig, F Heller, AH Gitter, M Fromm Annals of the New York Academy of Sciences 1072 (1), 288-299, 2006 | 225 | 2006 |
| Protective mucosal immunity mediated by epithelial CD1d and IL-10 T Olszak, JF Neves, CM Dowds, K Baker, J Glickman, NO Davidson, ... Nature 509 (7501), 497-502, 2014 | 222 | 2014 |
| HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants GA Heap, MN Weedon, CM Bewshea, A Singh, M Chen, JB Satchwell, ... Nature genetics 46 (10), 1131-1134, 2014 | 216 | 2014 |
| Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease S Zeissig, E Rosati, CM Dowds, K Aden, J Bethge, B Schulte, WH Pan, ... Gut 68 (1), 25-39, 2019 | 215 | 2019 |
