مقاله‌های دارای تعهدات انتشار عمومی - Richard Meadبیشتر بدانید
جای دیگری دردسترس نیست: یک
مرور
Assessment of the Precision in Measuring Glutathione at 3 T With a MEGA‐PRESS Sequence in Primary Motor Cortex and Occipital Cortex‏
A Anton, RJ Mead, PJ Shaw, RAE Edden, J Bigley, TM Jenkins, JM Wild, ...‏
Journal of Magnetic Resonance Imaging 55 (2), 435-442, 2022‏
تعهدات: US National Institutes of Health, Canadian Institutes of Health Research, UK …‏
جای دیگری دردسترس است: ۲۸
مرور
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases‏
MA Myszczynska, PN Ojamies, AMB Lacoste, D Neil, A Saffari, R Mead, ...‏
Nature reviews neurology 16 (8), 440-456, 2020‏
تعهدات: Motor Neurone Disease Association, UK, UK Medical Research Council‏
مرور
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation‏
RJ Mead, N Shan, HJ Reiser, F Marshall, PJ Shaw‏
Nature Reviews Drug Discovery 22 (3), 185-212, 2023‏
تعهدات: US Department of Defense, Motor Neurone Disease Association, UK, UK Medical …‏
مرور
TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD‏
MA White, E Kim, A Duffy, R Adalbert, BU Phillips, OM Peters, ...‏
Nature neuroscience 21 (4), 552-563, 2018‏
تعهدات: US National Institutes of Health, UK Biotechnology and Biological Sciences …‏
مرور
Optimised and Rapid Pre-clinical Screening in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)‏
RJ Mead, EJ Bennett, AJ Kennerley, P Sharp, C Sunyach, P Kasher, ...‏
PloS one 6 (8), e23244, 2011‏
تعهدات: US National Institutes of Health‏
مرور
Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss‏
MA White, Z Lin, E Kim, CM Henstridge, E Pena Altamira, CK Hunt, ...‏
Acta neuropathologica communications 7, 1-16, 2019‏
تعهدات: Alzheimers's UK, Motor Neurone Disease Association, UK, UK Medical Research …‏
مرور
S [+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis‏
RJ Mead, A Higginbottom, SP Allen, J Kirby, E Bennett, SC Barber, ...‏
Free Radical Biology and Medicine 61, 438-452, 2013‏
تعهدات: US National Institutes of Health, Wellcome Trust‏
مرور
Advances, challenges and future directions for stem cell therapy in amyotrophic lateral sclerosis‏
Y Ciervo, K Ning, X Jun, PJ Shaw, RJ Mead‏
Molecular neurodegeneration 12, 1-22, 2017‏
تعهدات: Motor Neurone Disease Association, UK, UK Medical Research Council, National …‏
مرور
NRF2 as a therapeutic opportunity to impact in the molecular roadmap of ALS‏
J Jiménez-Villegas, L Ferraiuolo, RJ Mead, PJ Shaw, A Cuadrado, ...‏
Free Radical Biology and Medicine 173, 125-141, 2021‏
تعهدات: Motor Neurone Disease Association, UK, UK Medical Research Council, National …‏
مرور
Extensive phenotypic characterisation of a human TDP-43Q331K transgenic mouse model of amyotrophic lateral sclerosis (ALS)‏
JA Watkins, JJP Alix, PJ Shaw, RJ Mead‏
Scientific reports 11 (1), 16659, 2021‏
تعهدات: Motor Neurone Disease Association, UK, UK Medical Research Council, National …‏
مرور
Early Detection of Motor Dysfunction in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Using Home Cage Running Wheels‏
EJ Bennett, RJ Mead, M Azzouz, PJ Shaw, AJ Grierson‏
PLoS One 9 (9), e107918, 2014‏
تعهدات: US National Institutes of Health, Motor Neurone Disease Association, UK …‏
مرور
Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS‏
Y Ciervo, N Gatto, C Allen, A Grierson, L Ferraiuolo, RJ Mead, PJ Shaw‏
Molecular Therapy Methods & Clinical Development 21, 413-433, 2021‏
تعهدات: Motor Neurone Disease Association, UK, UK Medical Research Council, National …‏
مرور
In Vivo Fiber Optic Raman Spectroscopy of Muscle in Preclinical Models of Amyotrophic Lateral Sclerosis and Duchenne Muscular Dystrophy‏
M Plesia, OA Stevens, GR Lloyd, CA Kendall, I Coldicott, AJ Kennerley, ...‏
ACS chemical neuroscience 12 (10), 1768-1776, 2021‏
تعهدات: Alzheimers's UK, UK Medical Research Council, National Institute for Health …‏
مرور
Female sex mitigates motor and behavioural phenotypes in TDP-43Q331K knock-in mice‏
J Watkins, A Ghosh, AFA Keerie, JJP Alix, RJ Mead, J Sreedharan‏
Scientific Reports 10 (1), 19220, 2020‏
تعهدات: Alzheimers's UK, Motor Neurone Disease Association, UK, UK Medical Research …‏
مرور
Proteomic approaches to study cysteine oxidation: applications in neurodegenerative diseases‏
TK Pham, WA Buczek, RJ Mead, PJ Shaw, MO Collins‏
Frontiers in Molecular Neuroscience 14, 678837, 2021‏
تعهدات: Motor Neurone Disease Association, UK, UK Medical Research Council, National …‏
مرور
A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins‏
LM Castelli, YH Lin, A Sanchez-Martinez, A Gül, K Mohd Imran, ...‏
Science translational medicine 15 (685), eabo3823, 2023‏
تعهدات: Academy of Medical Sciences, UK, Alzheimers's UK, UK Biotechnology and …‏
مرور
Janus kinase inhibitors are potential therapeutics for amyotrophic lateral sclerosis‏
PJ Richardson, DP Smith, A de Giorgio, X Snetkov, J Almond-Thynne, ...‏
Translational Neurodegeneration 12 (1), 47, 2023‏
تعهدات: National Institute for Health Research, UK‏
مرور
The GLP-1 receptor agonist, liraglutide, fails to slow disease progression in SOD1G93A and TDP-43Q331K transgenic mouse models of ALS‏
A Keerie, H Brown-Wright, I Kirkland, A Grierson, JJP Alix, C Holscher, ...‏
Scientific Reports 11 (1), 17027, 2021‏
تعهدات: Motor Neurone Disease Association, UK, National Institute for Health …‏
مرور
Atypical TDP‐43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP‏
J Cooper‐Knock, TH Julian, E Feneberg, JR Highley, M Sidra, MR Turner, ...‏
Brain Pathology 33 (1), e13104, 2023‏
تعهدات: UK Biotechnology and Biological Sciences Research Council, Motor Neurone …‏
مرور
Fiber optic Raman spectroscopy for the evaluation of disease state in Duchenne muscular dystrophy: An assessment using the mdx model and human muscle‏
JJP Alix, M Plesia, SA Hool, I Coldicott, CA Kendall, PJ Shaw DBE, ...‏
Muscle & Nerve 66 (3), 362-369, 2022‏
تعهدات: Alzheimers's UK, UK Medical Research Council, National Institute for Health …‏
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