دنبال کردن
Shraddha Sadekar
Shraddha Sadekar
Translational PKPD,Genentech
ایمیل تأیید شده در gene.com
عنوان
نقل شده توسط
نقل شده توسط
سال
Transepithelial transport and toxicity of PAMAM dendrimers: implications for oral drug delivery
S Sadekar, H Ghandehari
Advanced drug delivery reviews 64 (6), 571-588, 2012
3522012
Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles
K Greish, G Thiagarajan, H Herd, R Price, H Bauer, D Hubbard, A Burckle, ...
Nanotoxicology 6 (7), 713-723, 2012
1982012
Guided delivery of polymer therapeutics using plasmonic photothermal therapy
AJ Gormley, N Larson, S Sadekar, R Robinson, A Ray, H Ghandehari
Nano today 7 (3), 158-167, 2012
1262012
Poly (amido amine) dendrimers as absorption enhancers for oral delivery of camptothecin
S Sadekar, G Thiagarajan, K Bartlett, D Hubbard, A Ray, LD McGill, ...
International journal of pharmaceutics 456 (1), 175-185, 2013
1162013
Comparative biodistribution of PAMAM dendrimers and HPMA copolymers in ovarian-tumor-bearing mice
S Sadekar, A Ray, M Janat-Amsbury, CM Peterson, H Ghandehari
Biomacromolecules 12 (1), 88-96, 2011
1072011
Evidence of oral translocation of anionic G6. 5 dendrimers in mice
G Thiagarajan, S Sadekar, K Greish, A Ray, H Ghandehari
Molecular pharmaceutics 10 (3), 988-998, 2013
452013
Antibody drug conjugates: application of quantitative pharmacology in modality design and target selection
S Sadekar, I Figueroa, M Tabrizi
The AAPS journal 17, 828-836, 2015
422015
Comparative pharmacokinetics of PAMAM-OH dendrimers and HPMA copolymers in ovarian tumor-bearing mice
S Sadekar, O Linares, GJ Noh, D Hubbard, A Ray, M Janát-Amsbury, ...
Drug delivery and translational research 3, 260-271, 2013
312013
Translational approaches for brain delivery of biologics via cerebrospinal fluid
SS Sadekar, M Bowen, H Cai, S Jamalian, H Rafidi, W Shatz‐Binder, ...
Clinical Pharmacology & Therapeutics 111 (4), 826-834, 2022
242022
Neutral or detrimental effects of TREM2 agonist antibodies in preclinical models of Alzheimer’s disease and multiple sclerosis
A Etxeberria, YAA Shen, S Vito, SM Silverman, J Imperio, G Lalehzadeh, ...
Journal of Neuroscience 44 (29), 2024
32024
A novel approach to quantitate biodistribution and transduction of adeno-associated virus gene therapy using radiolabeled AAV vectors in mice
H Wang, R Li, S Sadekar, AV Kamath, BQ Shen
Molecular Therapy Methods & Clinical Development 32 (3), 2024
12024
Exploring How Antibody Format Drives Clearance from the Brain
K Schwinghamer, BM Kopec, E Ayewoh, X Tao, S Sadekar, A Sreedhara, ...
Molecular Pharmaceutics 21 (9), 4416-4429, 2024
12024
Modified antibody fcs and methods of use
GA Lazar, J Ernst, J Atwal, SS Sadekar, Y Yang, S Chung
US Patent App. 17/343,543, 2022
12022
Primate cerebrospinal fluid CHI3L1 reflects brain TREM2 agonism
SP Schauer, CH Cho, G Novikova, GA Roth, J Lee, AD Sharma, AR Foley, ...
Alzheimer's & Dementia 20 (9), 5861-5888, 2024
2024
Evaluation of Tumor Growth Inhibition in Preclinical Tumor Models: A Quantitative Approach
S Sadekar, I Figueroa, H Shankaran
Development of Antibody-Based Therapeutics: Translational Considerations …, 2018
2018
Stimulus-Response Mechanisms: An Overview
MA Tabrizi, SS Sadekar, I Figueroa, AM Ovacik
Development of Antibody-Based Therapeutics: Translational Considerations …, 2018
2018
Poly (amido amine) dendrimers: Role of architectural features on biodistribution and oral absorption enhancement
SS Sadekar
The University of Utah, 2013
2013
Correction to Comparative Biodistribution of PAMAM Dendrimers and HPMA Copolymers in Ovarian-Tumor-Bearing Mice
S Sadekar, A Ray, M Janàt-Amsbury, CM Peterson, H Ghandehari
Biomacromolecules 12 (9), 3351, 2011
2011
Influence of nanoconstruct architecture on biodistribution in ovarian tumor-bearing mice
H Ghandehari, A Ray, S Sadekar, A Anwar, CM Peterson, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010
2010
Oral disposition of G3. 5 PAMAM dendrimer across mice intestinal epithelia and anticancer activity of its drug conjugate
G Thiagarajan, A Ray, L Götz, D Hubbard, S Sadekar, R Price, ...
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مقاله‌ها 1–20