Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis M Camps, T Rückle, H Ji, V Ardissone, F Rintelen, J Shaw, C Ferrandi, ... Nature medicine 11 (9), 936-943, 2005 | 918 | 2005 |
Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ V Pomel, J Klicic, D Covini, DD Church, JP Shaw, K Roulin, ... Journal of medicinal chemistry 49 (13), 3857-3871, 2006 | 251 | 2006 |
Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia C Hetz, PA Vitte, A Bombrun, TK Rostovtseva, S Montessuit, A Hiver, ... Journal of Biological Chemistry 280 (52), 42960-42970, 2005 | 233 | 2005 |
Inhibition of c‐Jun N‐terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats C Ferrandi, R Ballerio, P Gaillard, C Giachetti, S Carboni, PA Vitte, ... British Journal of Pharmacology 142 (6), 953-960, 2004 | 224 | 2004 |
Regulation of the severity of neuroinflammation and demyelination by TLR‐ASK1‐p38 pathway X Guo, C Harada, K Namekata, A Matsuzawa, M Camps, H Ji, D Swinnen, ... EMBO Molecular Medicine 2 (12), 504-515, 2010 | 167 | 2010 |
Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl) acetonitrile inhibitors of the c-Jun N-terminal kinase P Gaillard, I Jeanclaude-Etter, V Ardissone, S Arkinstall, Y Cambet, ... Journal of medicinal chemistry 48 (14), 4596-4607, 2005 | 145 | 2005 |
AS601245 (1, 3-Benzothiazol-2-yl (2-{[2-(3-pyridinyl) ethyl] amino}-4 pyrimidinyl) Acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties S Carboni, A Hiver, C Szyndralewiez, P Gaillard, JP Gotteland, PA Vitte The Journal of pharmacology and experimental therapeutics 310 (1), 25-32, 2004 | 135 | 2004 |
Control of death receptor and mitochondrial‐dependent apoptosis by c‐Jun N‐terminal kinase in hippocampal CA1 neurones following global transient ischaemia S Carboni, B Antonsson, P Gaillard, JP Gotteland, JY Gillon, PA Vitte Journal of neurochemistry 92 (5), 1054-1060, 2005 | 93 | 2005 |
Interleukin-6 protects against paclitaxel, cisplatin and vincristine-induced neuropathies without impairing chemotherapeutic activity N Callizot, E Andriambeloson, J Glass, M Revel, P Ferro, R Cirillo, ... Cancer chemotherapy and pharmacology 62, 995-1007, 2008 | 84 | 2008 |
An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo TM Handel, Z Johnson, DH Rodrigues, AC Dos Santos, R Cirillo, V Muzio, ... Journal of Leucocyte Biology 84 (4), 1101-1108, 2008 | 78 | 2008 |
Interleukin‐6 attenuates the development of experimental diabetes‐related neuropathy E Andriambeloson, C Baillet, PA Vitte, G Garotta, M Dreano, N Callizot Neuropathology 26 (1), 32-42, 2006 | 66 | 2006 |
AS601245, a c‐Jun NH2‐terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils S Carboni, U Boschert, P Gaillard, JP Gotteland, JY Gillon, PA Vitte British journal of pharmacology 153 (1), 157-163, 2008 | 63 | 2008 |
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells C Volpi, G Mondanelli, MT Pallotta, C Vacca, A Iacono, M Gargaro, ... Neuropharmacology 102, 59-71, 2016 | 31 | 2016 |
Beneficial effects of rh-CLU on disease severity in different animal models of peripheral neuropathies G Dati, A Quattrini, L Bernasconi, MC Malaguti, B Antonsson, F Nicoletti, ... Journal of neuroimmunology 190 (1-2), 8-17, 2007 | 29 | 2007 |
GLEPP1/Protein-Tyrosine Phosphatase ϕ Inhibitors Block Chemotaxis in Vitro and in Vivo and Improve Murine Ulcerative Colitis RP Gobert, M van den Eijnden, C Szyndralewiez, C Jorand-Lebrun, ... Journal of Biological Chemistry 284 (17), 11385-11395, 2009 | 23 | 2009 |
An adiponectin-like molecule with antidiabetic properties T Sulpice, B Prunet-Marcassus, C Molveaux, PD Cani, PA Vitte, P Graber, ... Endocrinology 150 (10), 4493-4501, 2009 | 18 | 2009 |
Benzothiazole derivatives for the treatment of diabetes P Gaillard, JP Gotteland, PA Vitte US Patent App. 10/571,291, 2007 | 17 | 2007 |
A novel insight into the mechanism of the antithrombotic action of defibrotide R Tettamanti, G Bianchi, PA Vitte, G Kato, R Porta, C Thiemermann, ... Life sciences 51 (19), 1545-1555, 1992 | 12 | 1992 |
Use of Sdf-1 for the Treatment and/or Prevention of Neurological Diseases U Boschert, A Proudfoot, L Kadi, PA Vitte, J Wojcik US Patent App. 12/067,224, 2008 | 11 | 2008 |
Discovery of a novel series of potent S1P1 agonists S Crosignani, A Bombrun, D Covini, M Maio, D Marin, A Quattropani, ... Bioorganic & Medicinal Chemistry Letters 20 (5), 1516-1519, 2010 | 9 | 2010 |