Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ... Nature 488 (7409), 49, 2012 | 1018 | 2012 |
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 669 | 2014 |
Cytogenetic prognostication within medulloblastoma subgroups DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ... Journal of Clinical Oncology 32 (9), 886-896, 2014 | 373 | 2014 |
Divergent clonal selection dominates medulloblastoma at recurrence AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ... Nature 529 (7586), 351-357, 2016 | 364 | 2016 |
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101, 2018 | 213 | 2018 |
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ... Acta neuropathologica 126 (6), 917-929, 2013 | 204 | 2013 |
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma AM Dubuc, M Remke, A Korshunov, PA Northcott, SH Zhan, ... Acta neuropathologica 125 (3), 373-384, 2013 | 198 | 2013 |
Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells X Wang, C Venugopal, B Manoranjan, N McFarlane, E O'Farrell, S Nolte, ... Oncogene 31 (2), 187-199, 2012 | 169 | 2012 |
Medulloblastoma subgroup-specific outcomes in irradiated children: who are the true high-risk patients? V Ramaswamy, M Remke, J Adamski, U Bartels, U Tabori, X Wang, ... Neuro-oncology 18 (2), 291-297, 2015 | 166 | 2015 |
Spatial heterogeneity in medulloblastoma AS Morrissy, FMG Cavalli, M Remke, V Ramaswamy, DJH Shih, ... Nature Genetics 49 (5), 780-788, 2017 | 150 | 2017 |
A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases L Garzia, N Kijima, AS Morrissy, P De Antonellis, A Guerreiro-Stucklin, ... Cell 172 (5), 1050-1062. e14, 2018 | 145 | 2018 |
Medulloblastoma subgroups remain stable across primary and metastatic compartments X Wang, AM Dubuc, V Ramaswamy, S Mack, DMA Gendoo, M Remke, ... Acta neuropathologica 129 (3), 449-457, 2015 | 102 | 2015 |
FoxG1 Interacts with Bmi1 to Regulate Self‐Renewal and Tumorigenicity of Medulloblastoma Stem Cells B Manoranjan, X Wang, RM Hallett, C Venugopal, SC Mack, N McFarlane, ... Stem Cells 31 (7), 1266-1277, 2013 | 79 | 2013 |
Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma CC Faria, BJ Golbourn, AM Dubuc, M Remke, RJ Diaz, S Agnihotri, ... Cancer research, 2014 | 63 | 2014 |
Duration of the pre‐diagnostic interval in medulloblastoma is subgroup dependent V Ramaswamy, M Remke, D Shih, X Wang, PA Northcott, CC Faria, ... Pediatric blood & cancer 61 (7), 1190-1194, 2014 | 63 | 2014 |
Deconstruction of medulloblastoma cellular heterogeneity reveals differences between the most highly invasive and self-renewing phenotypes LC Morrison, R McClelland, C Aiken, M Bridges, L Liang, X Wang, ... Neoplasia 15 (4), 384IN6-398IN8, 2013 | 55 | 2013 |
Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells C Venugopal, N Li, X Wang, B Manoranjan, C Hawkins, T Gunnarsson, ... Stem cell research 8 (2), 141-153, 2012 | 52 | 2012 |
Spinal myxopapillary ependymomas demonstrate a warburg phenotype SC Mack, S Agnihotri, KC Bertrand, X Wang, DJ Shih, H Witt, N Hill, ... Clinical Cancer Research 21 (16), 3750-3758, 2015 | 51 | 2015 |
Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis IS Shimada, SH Hwang, BN Somatilaka, X Wang, P Skowron, J Kim, ... Cell reports 22 (5), 1169-1184, 2018 | 50 | 2018 |
The Rising Challenge of Training Physician–scientists: Recommendations From a Canadian National Consensus Conference MJ Strong, N Busing, DL Goosney, KA Harris, T Horsley, A Kuzyk, ... Academic Medicine, 2017 | 50 | 2017 |