دنبال کردن
John Paul Shen
John Paul Shen
Assistant Professor, University of Texas MD Anderson Cancer Center
ایمیل تأیید شده در alum.mit.edu - صفحهٔ اصلی
عنوان
نقل شده توسط
نقل شده توسط
سال
Integrated genomic characterization of papillary thyroid carcinoma‏
N Agrawal, R Akbani, BA Aksoy, A Ally, H Arachchi, SL Asa, JT Auman, ...‏
Cell 159 (3), 676-690, 2014‏
27712014
Network-based stratification of tumor mutations‏
M Hofree, JP Shen, H Carter, A Gross, T Ideker‏
Nature methods 10 (11), 1108-1115, 2013‏
9192013
Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions‏
JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ...‏
Nature methods 14 (6), 573-576, 2017‏
3952017
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease‏
JE Bradner, R Mak, SK Tanguturi, R Mazitschek, SJ Haggarty, K Ross, ...‏
Proceedings of the National Academy of Sciences 107 (28), 12617-12622, 2010‏
2322010
Novel third-generation EGFR tyrosine kinase inhibitors and strategies to overcome therapeutic resistance in lung cancer‏
A Murtuza, A Bulbul, JP Shen, P Keshavarzian, BD Woodward, ...‏
Cancer Research 79 (4), 689-698, 2019‏
1982019
Genetic interaction mapping in mammalian cells using CRISPR interference‏
D Du, A Roguev, DE Gordon, M Chen, SH Chen, M Shales, JP Shen, ...‏
Nature methods 14 (6), 577-580, 2017‏
1752017
A network of conserved synthetic lethal interactions for exploration of precision cancer therapy‏
R Srivas, JP Shen, CC Yang, SM Sun, J Li, AM Gross, J Jensen, K Licon, ...‏
Molecular cell 63 (3), 514-525, 2016‏
1682016
A robust small-molecule microarray platform for screening cell lysates‏
JE Bradner, OM McPherson, R Mazitschek, D Barnes-Seeman, JP Shen, ...‏
Chemistry & biology 13 (5), 493-504, 2006‏
1612006
Phase 1/2 study of ARV-110, an androgen receptor (AR) PROTAC degrader, in metastatic castration-resistant prostate cancer (mCRPC).‏
X Gao, HA Burris III, J Vuky, R Dreicer, AO Sartor, CN Sternberg, ...‏
Journal of Clinical Oncology 40 (6_suppl), 17-17, 2022‏
1522022
A global transcriptional network connecting noncoding mutations to changes in tumor gene expression‏
W Zhang, A Bojorquez-Gomez, DO Velez, G Xu, KS Sanchez, JP Shen, ...‏
Nature genetics 50 (4), 613-620, 2018‏
1522018
Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients‏
J Ma, SH Fong, Y Luo, CJ Bakkenist, JP Shen, S Mourragui, LFA Wessels, ...‏
Nature Cancer 2 (2), 233-244, 2021‏
1512021
Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss‏
AM Gross, RK Orosco, JP Shen, AM Egloff, H Carter, M Hofree, ...‏
Nature genetics 46 (9), 939-943, 2014‏
1482014
Patient-derived micro-organospheres enable clinical precision oncology‏
S Ding, C Hsu, Z Wang, NR Natesh, R Millen, M Negrete, N Giroux, ...‏
Cell Stem Cell 29 (6), 905-917. e6, 2022‏
1112022
Survival improvement for patients with metastatic colorectal cancer over twenty years‏
FA Zeineddine, MA Zeineddine, A Yousef, Y Gu, S Chowdhury, A Dasari, ...‏
NPJ Precision Oncology 7 (1), 16, 2023‏
842023
Genomic landscape of appendiceal neoplasms‏
CSP Ang, JP Shen, CJ Hardy-Abeloos, JK Huang, JS Ross, VA Miller, ...‏
JCO Precision Oncology 2, 1-18, 2018‏
842018
Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers‏
B Garmezy, J Gheeya, HY Lin, Y Huang, T Kim, X Jiang, KZ Thein, ...‏
JCO Precision Oncology 6, e2100267, 2022‏
832022
Phase I/II trial of encorafenib, cetuximab, and nivolumab in patients with microsatellite stable, BRAFV600E metastatic colorectal cancer.‏
VK Morris, CM Parseghian, M Escano, B Johnson, KPS Raghav, A Dasari, ...‏
Journal of Clinical Oncology 40 (4_suppl), 12-12, 2022‏
782022
Comprehensive Clinical and Molecular Characterization of KRASG12C-Mutant Colorectal Cancer‏
JT Henry, O Coker, S Chowdhury, JP Shen, VK Morris, A Dasari, ...‏
JCO Precision Oncology 5, 613-621, 2021‏
782021
Relative abundance of SARS-CoV-2 entry genes in the enterocytes of the lower gastrointestinal tract‏
JJ Lee, S Kopetz, E Vilar, JP Shen, K Chen, A Maitra‏
Genes 11 (6), 645, 2020‏
712020
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression‏
S Cao, JR Wang, S Ji, P Yang, Y Dai, S Guo, MD Montierth, JP Shen, ...‏
Nature biotechnology 40 (11), 1624-1633, 2022‏
602022
سیستم در حال حاضر قادر به انجام عملکرد نیست. بعداً دوباره امتحان کنید.
مقاله‌ها 1–20