The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis? F Genovese, AA Manresa, DJ Leeming, MA Karsdal, P Boor Fibrogenesis & tissue repair 7, 1-14, 2014 | 383 | 2014 |
Extracellular matrix remodeling: the common denominator in connective tissue diseases possibilities for evaluation and current understanding of the matrix as more than a … MA Karsdal, MJ Nielsen, JM Sand, K Henriksen, F Genovese, ... Assay and drug development technologies 11 (2), 70-92, 2013 | 297 | 2013 |
Novel insights into the function and dynamics of extracellular matrix in liver fibrosis MA Karsdal, T Manon-Jensen, F Genovese, JH Kristensen, MJ Nielsen, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (10 …, 2015 | 257 | 2015 |
Molecular serum markers of liver fibrosis T Liu, X Wang, MA Karsdal, DJ Leeming, F Genovese Biomarker insights 7, BMI. S10009, 2012 | 240 | 2012 |
Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF PF Mercer, HV Woodcock, JD Eley, M Platé, MG Sulikowski, ... Thorax 71 (8), 701-711, 2016 | 217 | 2016 |
Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to … LR Ranganath, AM Milan, AT Hughes, JJ Dutton, R Fitzgerald, MC Briggs, ... Annals of the Rheumatic Diseases 75 (2), 362-367, 2016 | 179 | 2016 |
Understanding cardiac extracellular matrix remodeling to develop biomarkers of myocardial infarction outcomes SH Nielsen, AJ Mouton, KY DeLeon-Pennell, F Genovese, M Karsdal, ... Matrix Biology 75, 43-57, 2019 | 156 | 2019 |
Collagen and tissue turnover as a function of age: Implications for fibrosis MA Karsdal, F Genovese, EA Madsen, T Manon-Jensen, D Schuppan Journal of hepatology 64 (1), 103-109, 2016 | 115 | 2016 |
Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’in Italy M Nemethova, J Radvanszky, L Kadasi, DB Ascher, DEV Pires, ... European Journal of Human Genetics 24 (1), 66-72, 2016 | 109 | 2016 |
Serological investigation of the collagen degradation profile of patients with chronic obstructive pulmonary disease or idiopathic pulmonary fibrosis DJ Leeming, JM Sand, MJ Nielsen, F Genovese, FJ Martinez, ... Biomarker insights 7, BMI. S9415, 2012 | 109 | 2012 |
RAAS inhibitors directly reduce diabetes‐induced renal fibrosis via growth factor inhibition S Koszegi, A Molnar, L Lenart, J Hodrea, DB Balogh, T Lakat, ... The Journal of physiology 597 (1), 193-209, 2019 | 88 | 2019 |
Serological assessment of activated fibroblasts by alpha-smooth muscle actin (α-SMA): a noninvasive biomarker of activated fibroblasts in lung disorders SH Nielsen, N Willumsen, DJ Leeming, SJ Daniels, S Brix, MA Karsdal, ... Translational oncology 12 (2), 368-374, 2019 | 79 | 2019 |
Serum endotrophin, a type VI collagen cleavage product, is associated with increased mortality in chronic kidney disease A Fenton, MD Jesky, CJ Ferro, J Sørensen, MA Karsdal, P Cockwell, ... PLoS One 12 (4), e0175200, 2017 | 77 | 2017 |
The importance of extracellular matrix for cell function and in vivo likeness NUB Hansen, F Genovese, DJ Leeming, MA Karsdal Experimental and molecular pathology 98 (2), 286-294, 2015 | 76 | 2015 |
Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease C Fox, P Cocchiaro, F Oakley, R Howarth, K Callaghan, J Leslie, S Luli, ... Scientific Reports 6 (1), 20101, 2016 | 72 | 2016 |
Turnover of type III collagen reflects disease severity and is associated with progression and microinflammation in patients with IgA nephropathy F Genovese, P Boor, M Papasotiriou, DJ Leeming, MA Karsdal, J Floege Nephrology Dialysis Transplantation 31 (3), 472-479, 2016 | 70 | 2016 |
Serum and urine markers of collagen degradation reflect renal fibrosis in experimental kidney diseases M Papasotiriou, F Genovese, BM Klinkhammer, U Kunter, SH Nielsen, ... Nephrology Dialysis Transplantation 30 (7), 1112-1121, 2015 | 68 | 2015 |
Urinary endotrophin predicts disease progression in patients with chronic kidney disease DGK Rasmussen, A Fenton, M Jesky, C Ferro, P Boor, M Tepel, ... Scientific reports 7 (1), 17328, 2017 | 66 | 2017 |
Serum endotrophin identifies optimal responders to PPARγ agonists in type 2 diabetes MA Karsdal, K Henriksen, F Genovese, DJ Leeming, MJ Nielsen, BJ Riis, ... Diabetologia 60, 50-59, 2017 | 66 | 2017 |
Higher collagen VI formation is associated with all-cause mortality in patients with type 2 diabetes and microalbuminuria DGK Rasmussen, TW Hansen, BJ Von Scholten, SH Nielsen, H Reinhard, ... Diabetes Care 41 (7), 1493-1500, 2018 | 65 | 2018 |