دنبال کردن
Stephen Neidle
Stephen Neidle
Emeritus Professor of Chemical Biology, The UCL School of Pharmacy, University of London
ایمیل تأیید شده در ucl.ac.uk - صفحهٔ اصلی
عنوان
نقل شده توسط
نقل شده توسط
سال
Quadruplex DNA: sequence, topology and structure‏
S Burge, GN Parkinson, P Hazel, AK Todd, S Neidle‏
Nucleic acids research 34 (19), 5402-5415, 2006‏
27342006
Crystal structure of parallel quadruplexes from human telomeric DNA‏
GN Parkinson, MPH Lee, S Neidle‏
Nature 417 (6891), 876-880, 2002‏
24242002
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?‏
S Balasubramanian, LH Hurley, S Neidle‏
Nature reviews Drug discovery 10 (4), 261-275, 2011‏
18242011
Nucleic acids in chemistry and biology‏
GM Blackburn‏
Royal Society of Chemistry, 2006‏
13592006
Highly prevalent putative quadruplex sequence motifs in human DNA‏
AK Todd, M Johnston, S Neidle‏
Nucleic acids research 33 (9), 2901-2907, 2005‏
11632005
Inhibition of human telomerase by a G-quadruplex-interactive compound‏
D Sun, B Thompson, BE Cathers, M Salazar, SM Kerwin, JO Trent, ...‏
Journal of medicinal chemistry 40 (14), 2113-2116, 1997‏
10981997
Telomere maintenance as a target for anticancer drug discovery‏
S Neidle, G Parkinson‏
Nature Reviews Drug Discovery 1 (5), 383-393, 2002‏
8142002
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function‏
AM Burger, F Dai, CM Schultes, AP Reszka, MJ Moore, JA Double, ...‏
Cancer research 65 (4), 1489-1496, 2005‏
7422005
A standard reference frame for the description of nucleic acid base-pair geometry‏
WK Olson, M Bansal, SK Burley, RE Dickerson, M Gerstein, SC Harvey, ...‏
Journal of molecular biology 313 (1), 229-237, 2001‏
7162001
Putative DNA Quadruplex Formation within the Human c-kit Oncogene‏
S Rankin, AP Reszka, J Huppert, M Zloh, GN Parkinson, AK Todd, ...‏
Journal of the American Chemical Society 127 (30), 10584-10589, 2005‏
6832005
Human telomeric G‐quadruplex: The current status of telomeric G‐quadruplexes as therapeutic targets in human cancer‏
S Neidle‏
The FEBS journal 277 (5), 1118-1125, 2010‏
6752010
G-quadruplex nucleic acids as therapeutic targets‏
S Balasubramanian, S Neidle‏
Current opinion in chemical biology 13 (3), 345-353, 2009‏
6572009
DNA minor-groove recognition by small molecules‏
S Neidle‏
Natural product reports 18 (3), 291-309, 2001‏
6522001
Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors‏
M Read, RJ Harrison, B Romagnoli, FA Tanious, SH Gowan, AP Reszka, ...‏
Proceedings of the National Academy of Sciences 98 (9), 4844-4849, 2001‏
6392001
Quadruplex nucleic acids as novel therapeutic targets‏
S Neidle‏
Journal of medicinal chemistry 59 (13), 5987-6011, 2016‏
5952016
The structure of telomeric DNA‏
S Neidle, GN Parkinson‏
Current opinion in structural biology 13 (3), 275-283, 2003‏
5832003
Quadruplex nucleic acids‏
S Neidle, S Balasubramanian‏
Royal Society of Chemistry, 2006‏
5742006
Loop-length-dependent folding of G-quadruplexes‏
P Hazel, J Huppert, S Balasubramanian, S Neidle‏
Journal of the American Chemical Society 126 (50), 16405-16415, 2004‏
5632004
The structures of quadruplex nucleic acids and their drug complexes‏
S Neidle‏
Current opinion in structural biology 19 (3), 239-250, 2009‏
5252009
Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter‏
AT Phan, V Kuryavyi, S Burge, S Neidle, DJ Patel‏
Journal of the American Chemical Society 129 (14), 4386-4392, 2007‏
5112007
سیستم در حال حاضر قادر به انجام عملکرد نیست. بعداً دوباره امتحان کنید.
مقاله‌ها 1–20