| CREB family transcription factors are major mediators of BDNF transcriptional autoregulation in cortical neurons EE Esvald, J Tuvikene, A Sirp, S Patil, CR Bramham, T Timmusk Journal of Neuroscience 40 (7), 1405-1426, 2020 | 216 | 2020 |
| AP-1 transcription factors mediate BDNF-positive feedback loop in cortical neurons J Tuvikene, P Pruunsild, E Orav, EE Esvald, T Timmusk Journal of Neuroscience 36 (4), 1290-1305, 2016 | 99 | 2016 |
| Dopamine cross‐reacts with adrenoreceptors in cortical astrocytes to induce BDNF expression, CREB signaling and morphological transformation I Koppel, K Jaanson, A Klasche, J Tuvikene, T Tiirik, A Pärn, T Timmusk Glia 66 (1), 206-216, 2018 | 56 | 2018 |
| Intronic enhancer region governs transcript-specific Bdnf expression in rodent neurons J Tuvikene, EE Esvald, A Rähni, K Uustalu, A Zhuravskaya, A Avarlaid, ... Elife 10, e65161, 2021 | 29 | 2021 |
| Efficient use of a translation start codon in BDNF exon I I Koppel, J Tuvikene, I Lekk, T Timmusk Journal of Neurochemistry 134 (6), 1015-1025, 2015 | 28 | 2015 |
| Revisiting the expression of BDNF and its receptors in mammalian development EE Esvald, J Tuvikene, CS Kiir, A Avarlaid, L Tamberg, A Sirp, A Shubina, ... Frontiers in Molecular Neuroscience 16, 1182499, 2023 | 21 | 2023 |
| 2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer’s resilience A Kumar, SS Karuppagounder, Y Chen, C Corona, R Kawaguchi, ... Neuron 111 (18), 2831-2846. e10, 2023 | 19 | 2023 |
| Differential regulation of the BDNF gene in cortical and hippocampal neurons EE Esvald, J Tuvikene, A Moistus, K Rannaste, S Kõomägi, T Timmusk Journal of Neuroscience 42 (49), 9110-9128, 2022 | 19 | 2022 |
| The Fuchs corneal dystrophy-associated CTG repeat expansion in the TCF4 gene affects transcription from its alternative promoters A Sirp, K Leite, J Tuvikene, K Nurm, M Sepp, T Timmusk Scientific Reports 10 (1), 18424, 2020 | 18 | 2020 |
| Differential patterns of cross-reactive antibody response against SARS-CoV-2 spike protein detected for chronically ill and healthy COVID-19 naïve individuals M Jaago, A Rähni, N Pupina, A Pihlak, H Sadam, J Tuvikene, A Avarlaid, ... Scientific Reports 12 (1), 16817, 2022 | 15 | 2022 |
| Daughterless, the Drosophila orthologue of TCF4, is required for associative learning and maintenance of the synaptic proteome L Tamberg, M Jaago, K Säälik, A Sirp, J Tuvikene, A Shubina, CS Kiir, ... Disease models & mechanisms 13 (7), dmm042747, 2020 | 15 | 2020 |
| Electrochemical sensor based on molecularly imprinted polymer for rapid quantitative detection of brain-derived neurotrophic factor AG Ayankojo, R Boroznjak, J Reut, J Tuvikene, T Timmusk, V Syritski Sensors and Actuators B: Chemical 397, 134656, 2023 | 12 | 2023 |
| Functional consequences of TCF4 missense substitutions associated with Pitt-Hopkins syndrome, mild intellectual disability, and schizophrenia A Sirp, K Roots, K Nurm, J Tuvikene, M Sepp, T Timmusk Journal of Biological Chemistry 297 (6), 2021 | 12 | 2021 |
| Neuralized family member NEURL1 is a ubiquitin ligase for the cGMP-specific phosphodiesterase 9A K Taal, J Tuvikene, G Rullinkov, M Piirsoo, M Sepp, T Neuman, R Tamme, ... Scientific Reports 9 (1), 7104, 2019 | 12 | 2019 |
| Untranslated regions of brain-derived neurotrophic factor mRNA control its translatability and subcellular localization I Lekk, F Cabrera-Cabrera, G Turconi, J Tuvikene, EE Esvald, A Rähni, ... Journal of Biological Chemistry 299 (2), 2023 | 10 | 2023 |
| PCSK9 deficiency alters brain lipid composition without affecting brain development and function A Pärn, D Olsen, J Tuvikene, M Kaas, E Borisova, M Bilgin, M Elhauge, ... Frontiers in molecular neuroscience 15, 1084633, 2023 | 9 | 2023 |
| Expression of alternative transcription factor 4 mRNAs and protein isoforms in the developing and adult rodent and human tissues A Sirp, A Shubina, J Tuvikene, L Tamberg, CS Kiir, L Kranich, T Timmusk Frontiers in Molecular Neuroscience 15, 1033224, 2022 | 8 | 2022 |
| Melanoma-specific antigen-associated antitumor antibody reactivity as an immune-related biomarker for targeted immunotherapies A Rähni, M Jaago, H Sadam, N Pupina, A Pihlak, J Tuvikene, M Annuk, ... Communications Medicine 2 (1), 48, 2022 | 7 | 2022 |
| An 840 kb distant upstream enhancer is a crucial regulator of catecholamine‐dependent expression of the Bdnf gene in astrocytes A Avarlaid, EE Esvald, I Koppel, A Parkman, A Zhuravskaya, EV Makeyev, ... Glia 72 (1), 90-110, 2024 | 5 | 2024 |
| Isoform-specific reduction of the basic helix-loop-helix transcription factor TCF4 Levels in Huntington’s Disease K Nurm, M Sepp, C Castany-Pladevall, J Creus-Muncunill, J Tuvikene, ... Eneuro 8 (5), 2021 | 5 | 2021 |
