| RNA-guided genetic silencing systems in bacteria and archaea B Wiedenheft, SH Sternberg, JA Doudna Nature 482 (7385), 331-338, 2012 | 2716 | 2012 |
| Sequence-and structure-specific RNA processing by a CRISPR endonuclease RE Haurwitz, M Jinek, B Wiedenheft, K Zhou, JA Doudna Science 329 (5997), 1355-1358, 2010 | 1051 | 2010 |
| CRISPR-mediated adaptive immune systems in bacteria and archaea R Sorek, CM Lawrence, B Wiedenheft Annual review of biochemistry 82 (1), 237-266, 2013 | 884 | 2013 |
| Unravelling the structural and mechanistic basis of CRISPR–Cas systems J Van Der Oost, ER Westra, RN Jackson, B Wiedenheft Nature Reviews Microbiology 12 (7), 479-492, 2014 | 881 | 2014 |
| Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529-536, 2011 | 732 | 2011 |
| RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions B Wiedenheft, E van Duijn, JB Bultema, SP Waghmare, K Zhou, ... Proceedings of the National Academy of Sciences 108 (25), 10092-10097, 2011 | 720 | 2011 |
| Structures of the RNA-guided surveillance complex from a bacterial immune system B Wiedenheft, GC Lander, K Zhou, MM Jore, SJJ Brouns, J van der Oost, ... Nature 477 (7365), 486-489, 2011 | 603 | 2011 |
| Temporal detection and phylogenetic assessment of SARS-CoV-2 in municipal wastewater A Nemudryi, A Nemudraia, T Wiegand, K Surya, M Buyukyoruk, C Cicha, ... Cell Reports Medicine 1 (6), 2020 | 570 | 2020 |
| Mechanism of foreign DNA selection in a bacterial adaptive immune system DG Sashital, B Wiedenheft, JA Doudna Molecular cell 46 (5), 606-615, 2012 | 432 | 2012 |
| Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins J Bondy-Denomy, B Garcia, S Strum, M Du, MCF Rollins, ... Nature 526 (7571), 136-139, 2015 | 424 | 2015 |
| Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense B Wiedenheft, K Zhou, M Jinek, SM Coyle, W Ma, JA Doudna Structure 17 (6), 904-912, 2009 | 340 | 2009 |
| Endoribonuclease compositions and methods of use thereof RE Haurwitz, JA Doudna, B Wiedenheft, M Jinek US Patent 9,115,348, 2015 | 319 | 2015 |
| Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli RN Jackson, SM Golden, PBG van Erp, J Carter, ER Westra, SJJ Brouns, ... Science 345 (6203), 1473-1479, 2014 | 319 | 2014 |
| Type IE CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition ER Westra, E Semenova, KA Datsenko, RN Jackson, B Wiedenheft, ... PLoS genetics 9 (9), e1003742, 2013 | 289 | 2013 |
| Methods of generating nucleic acid fragments B Wiedenheft, K Zhou, JA Doudna US Patent 10,087,431, 2018 | 266 | 2018 |
| Surveillance and processing of foreign DNA by the Escherichia coli CRISPR-Cas system S Redding, SH Sternberg, M Marshall, B Gibb, P Bhat, CK Guegler, ... Cell 163 (4), 854-865, 2015 | 236 | 2015 |
| Structure reveals mechanisms of viral suppressors that intercept a CRISPR RNA-guided surveillance complex S Chowdhury, J Carter, MCF Rollins, SM Golden, RN Jackson, ... Cell 169 (1), 47-57. e11, 2017 | 233 | 2017 |
| Viruses from extreme thermal environments G Rice, K Stedman, J Snyder, B Wiedenheft, D Willits, S Brumfield, ... Proceedings of the National Academy of Sciences 98 (23), 13341-13345, 2001 | 229 | 2001 |
| Structural basis for promiscuous PAM recognition in type I–E Cascade from E. coli RP Hayes, Y Xiao, F Ding, PBG Van Erp, K Rajashankar, S Bailey, ... Nature 530 (7591), 499-503, 2016 | 208 | 2016 |
| Bacteriophage cooperation suppresses CRISPR-Cas3 and Cas9 immunity AL Borges, JY Zhang, MCF Rollins, BA Osuna, B Wiedenheft, ... Cell 174 (4), 917-925. e10, 2018 | 169 | 2018 |
