| Watermaze learning enhances excitability of CA1 pyramidal neurons MM Oh, AG Kuo, WW Wu, EA Sametsky, JF Disterhoft Journal of neurophysiology 90 (4), 2171-2179, 2003 | 217 | 2003 |
| Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment S Dutta, KC Chang, KA Beattie, J Sheng, PN Tran, WW Wu, M Wu, ... Frontiers in Physiology 8, 616, 2017 | 200 | 2017 |
| Age-related enhancement of the slow outward calcium-activated potassium current in hippocampal CA1 pyramidal neurons in vitro JM Power, WW Wu, E Sametsky, MM Oh, JF Disterhoft Journal of Neuroscience 22 (16), 7234-7243, 2002 | 184 | 2002 |
| Improving the in silico assessment of proarrhythmia risk by combining hERG (human ether-à-go-go-related gene) channel–drug binding kinetics and multichannel pharmacology Z Li, S Dutta, J Sheng, PN Tran, W Wu, K Chang, T Mdluli, DG Strauss, ... Circulation: Arrhythmia and Electrophysiology 10 (2), e004628, 2017 | 179 | 2017 |
| Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the CiPA Initiative Z Li, BJ Ridder, X Han, WW Wu, J Sheng, PN Tran, M Wu, A Randolph, ... Clinical Pharmacology & Therapeutics 105 (2), 466-475, 2019 | 154 | 2019 |
| Age-related biophysical alterations of hippocampal pyramidal neurons: implications for learning and memory WW Wu, MM Oh, JF Disterhoft Ageing research reviews 1 (2), 181-207, 2002 | 126 | 2002 |
| Biophysical alterations of hippocampal pyramidal neurons in learning, ageing and Alzheimer's disease JF Disterhoft, WW Wu, M Ohno Ageing research reviews 3 (4), 383-406, 2004 | 108 | 2004 |
| Comprehensive in vitro proarrhythmia assay (CiPA) update from a cardiac safety research consortium/health and environmental sciences institute/FDA meeting DG Strauss, G Gintant, Z Li, W Wu, K Blinova, J Vicente, JR Turner, ... Therapeutic Innovation & Regulatory Science 53 (4), 519-525, 2019 | 97 | 2019 |
| Uncertainty Quantification Reveals the Importance of Data Variability and Experimental Design Considerations for in Silico Proarrhythmia Risk Assessment KC Chang, S Dutta, GR Mirams, KA Beattie, J Sheng, PN Tran, M Wu, ... Frontiers in physiology 8, 917, 2017 | 92 | 2017 |
| Translational models and tools to reduce clinical trials and improve regulatory decision making for QTc and proarrhythmia risk (ICH E14/S7B updates) DG Strauss, WW Wu, Z Li, J Koerner, C Garnett Clinical Pharmacology & Therapeutics 109 (2), 319-333, 2021 | 78 | 2021 |
| Slow Afterhyperpolarization governs the development of NMDA Receptor–dependent afterdepolarization in CA1 pyramidal neurons during synaptic stimulation WW Wu, CS Chan, JF Disterhoft Journal of neurophysiology 92 (4), 2346-2356, 2004 | 77 | 2004 |
| Coupling of L-Type Ca2+ Channels to KV7/KCNQ Channels Creates a Novel, Activity-Dependent, Homeostatic Intrinsic Plasticity WW Wu, CS Chan, DJ Surmeier, JF Disterhoft Journal of neurophysiology 100 (4), 1897-1908, 2008 | 60 | 2008 |
| Ovarian hormone deficiency reduces intrinsic excitability and abolishes acute estrogen sensitivity in hippocampal CA1 pyramidal neurons WW Wu, JP Adelman, J Maylie Journal of Neuroscience 31 (7), 2638-2648, 2011 | 53 | 2011 |
| Developmental profile of SK2 channel expression and function in CA1 neurons C Ballesteros‐Merino, M Lin, WW Wu, C Ferrandiz‐Huertas, ... Hippocampus 22 (6), 1467-1480, 2012 | 44 | 2012 |
| A temperature-dependent in silico model of the human ether-à-go-go-related (hERG) gene channel Z Li, S Dutta, J Sheng, PN Tran, W Wu, T Colatsky Journal of pharmacological and toxicological methods 81, 233-239, 2016 | 43 | 2016 |
| A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ... Toxicology and applied pharmacology 394, 114961, 2020 | 42 | 2020 |
| Galantamine increases excitability of CA1 hippocampal pyramidal neurons MM Oh, WW Wu, JM Power, JF Disterhoft Neuroscience 137 (1), 113-123, 2006 | 36 | 2006 |
| IK1 channels do not contribute to the slow afterhyperpolarization in pyramidal neurons K Wang, P Mateos-Aparicio, C Hönigsperger, V Raghuram, WW Wu, ... Elife 5, e11206, 2016 | 31 | 2016 |
| Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block PN Tran, J Sheng, AL Randolph, CA Baron, N Thiebaud, M Ren, M Wu, ... PLoS One 15 (11), e0241362, 2020 | 25 | 2020 |
| Functional changes in hippocampal synaptic signaling in offspring survivors of a mouse model of intrauterine inflammation MH Kelley, WW Wu, J Lei, M McLane, H Xie, KD Hart, L Pereira, I Burd, ... Journal of neuroinflammation 14, 1-8, 2017 | 23 | 2017 |