LMO2-Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1 S Hacein-Bey-Abina, C Von Kalle, M Schmidt, MP McCormack, ... science 302 (5644), 415-419, 2003 | 4556 | 2003 |
Activation of the T-Cell Oncogene LMO2 after Gene Therapy for X-Linked Severe Combined Immunodeficiency MP McCormack, TH Rabbitts New England Journal of Medicine 350 (9), 913-922, 2004 | 441 | 2004 |
The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal MP McCormack, LF Young, S Vasudevan, CA de Graaf, R Codrington, ... Science 327 (5967), 879-883, 2010 | 284 | 2010 |
The LMO2 T-Cell Oncogene Is Activated via Chromosomal Translocations or Retroviral Insertion during Gene Therapy but Has No Mandatory Role in Normal T … MP McCormack, A Forster, L Drynan, R Pannell, TH Rabbitts Molecular and cellular biology 23 (24), 9003-9013, 2003 | 166 | 2003 |
Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer A Forster, R Pannell, LF Drynan, M McCormack, EC Collins, A Daser, ... Cancer cell 3 (5), 449-458, 2003 | 166 | 2003 |
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling S Goossens, E Radaelli, O Blanchet, K Durinck, J Van der Meulen, ... Nature communications 6 (1), 5794, 2015 | 95 | 2015 |
Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL MP McCormack, BJ Shields, JT Jackson, C Nasa, W Shi, NJ Slater, ... Blood, The Journal of the American Society of Hematology 122 (12), 2093-2103, 2013 | 78 | 2013 |
Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling CS Tremblay, FC Brown, M Collett, J Saw, SK Chiu, SE Sonderegger, ... Leukemia 30 (10), 1993-2001, 2016 | 67 | 2016 |
Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant G Rank, R Sutton, V Marshall, RJ Lundie, J Caddy, T Romeo, ... Blood, The Journal of the American Society of Hematology 113 (14), 3352-3362, 2009 | 64 | 2009 |
Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene MA Hall, NJ Slater, CG Begley, JM Salmon, LJ Van Stekelenburg, ... Molecular and cellular biology 25 (15), 6355-6362, 2005 | 61 | 2005 |
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis MP McCormack, MA Hall, SM Schoenwaelder, Q Zhao, S Ellis, ... Blood 108 (7), 2248-2256, 2006 | 58 | 2006 |
The molecular basis of Lmo2-induced T-cell acute lymphoblastic leukemia DJ Curtis, MP McCormack Clinical Cancer Research 16 (23), 5618-5623, 2010 | 53 | 2010 |
The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1 CL Carmichael, J Wang, T Nguyen, O Kolawole, A Benyoucef, ... Blood, The Journal of the American Society of Hematology 136 (8), 957-973, 2020 | 52 | 2020 |
The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms SL Siggins, NYN Nguyen, MP McCormack, S Vasudevan, R Villani, ... Blood, The Journal of the American Society of Hematology 114 (5), 995-1004, 2009 | 50 | 2009 |
A crucial role for the homeodomain transcription factor Hhex in lymphopoiesis JT Jackson, C Nasa, W Shi, ND Huntington, CW Bogue, WS Alexander, ... Blood, The Journal of the American Society of Hematology 125 (5), 803-814, 2015 | 47 | 2015 |
Fat grafting for facial rejuvenation KP Schultz, A Raghuram, MJ Davis, A Abu-Ghname, E Chamata, ... Seminars in plastic surgery 34 (01), 030-037, 2020 | 46 | 2020 |
PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia HM McRae, AL Garnham, Y Hu, MT Witkowski, MA Corbett, MP Dixon, ... Blood, The Journal of the American Society of Hematology 133 (16), 1729-1741, 2019 | 45 | 2019 |
Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a BJ Shields, JT Jackson, D Metcalf, W Shi, Q Huang, AL Garnham, ... Genes & development 30 (1), 78-91, 2016 | 40 | 2016 |
Expression of activated mutants of the human interleukin-3/interleukin-5/granulocyte-macrophage colony-stimulating factor receptor common β subunit in primary hematopoietic … MP McCormack, TJ Gonda Blood, The Journal of the American Society of Hematology 90 (4), 1471-1481, 1997 | 39 | 1997 |
Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene JM Salmon, NJ Slater, MA Hall, MP McCormack, SL Nutt, SM Jane, ... Blood, The Journal of the American Society of Hematology 110 (10), 3573-3581, 2007 | 33 | 2007 |