Gene silencing by microRNAs: contributions of translational repression and mRNA decay E Huntzinger, E Izaurralde Nature Reviews Genetics 12 (2), 99-110, 2011 | 2946 | 2011 |
Towards a molecular understanding of microRNA-mediated gene silencing S Jonas, E Izaurralde Nature reviews genetics 16 (7), 421-433, 2015 | 2142 | 2015 |
mRNA degradation by miRNAs and GW182 requires both CCR4: NOT deadenylase and DCP1: DCP2 decapping complexes I Behm-Ansmant, J Rehwinkel, T Doerks, A Stark, P Bork, E Izaurralde Genes & development 20 (14), 1885-1898, 2006 | 1427 | 2006 |
Getting to the root of miRNA-mediated gene silencing A Eulalio, E Huntzinger, E Izaurralde Cell 132 (1), 9-14, 2008 | 1400 | 2008 |
The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon junctions H Le Hir, E Izaurralde, LE Maquat, MJ Moore The EMBO journal, 2000 | 1195 | 2000 |
P bodies: at the crossroads of post-transcriptional pathways A Eulalio, I Behm-Ansmant, E Izaurralde Nature reviews Molecular cell biology 8 (1), 9-22, 2007 | 1141 | 2007 |
The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense‐mediated mRNA decay H Le Hir, D Gatfield, E Izaurralde, MJ Moore The EMBO journal, 2001 | 1047 | 2001 |
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing A Eulalio, I Behm-Ansmant, D Schweizer, E Izaurralde Molecular and cellular biology, 2007 | 886 | 2007 |
The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus E Izaurralde, U Kutay, C von Kobbe, IW Mattaj, D Görlich The EMBO journal, 1997 | 807 | 1997 |
TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus P Grüter, C Tabernero, C von Kobbe, C Schmitt, C Saavedra, A Bachi, ... Molecular cell 1 (5), 649-659, 1998 | 756 | 1998 |
A nuclear cap binding protein complex involved in pre-mRNA splicing E Izaurralde, J Lewis, C McGuigan, M Jankowska, E Darzynkiewicz, ... Cell 78 (4), 657-668, 1994 | 698 | 1994 |
A crucial role for GW182 and the DCP1: DCP2 decapping complex in miRNA-mediated gene silencing JAN Rehwinkel, I Behm-Ansmant, D Gatfield, E Izaurralde Rna 11 (11), 1640-1647, 2005 | 690 | 2005 |
Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain A Lingel, B Simon, E Izaurralde, M Sattler Nature 426 (6965), 465-469, 2003 | 649 | 2003 |
Deadenylation is a widespread effect of miRNA regulation A Eulalio, E Huntzinger, T Nishihara, J Rehwinkel, M Fauser, E Izaurralde Rna 15 (1), 21-32, 2009 | 617 | 2009 |
Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species E Conti, E Izaurralde Current opinion in cell biology 17 (3), 316-325, 2005 | 591 | 2005 |
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay A Eulalio, E Huntzinger, E Izaurralde Nature structural & molecular biology 15 (4), 346-353, 2008 | 565 | 2008 |
A novel class of RanGTP binding proteins D Görlich, M Dabrowski, FR Bischoff, U Kutay, P Bork, E Hartmann, ... The Journal of cell biology 138 (1), 65-80, 1997 | 559 | 1997 |
Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome TI Orban, E Izaurralde Rna 11 (4), 459-469, 2005 | 514 | 2005 |
GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets JE Braun, E Huntzinger, M Fauser, E Izaurralde Molecular cell 44 (1), 120-133, 2011 | 508 | 2011 |
Identification of a tRNA-specific nuclear export receptor U Kutay, G Lipowsky, E Izaurralde, FR Bischoff, P Schwarzmaier, ... Molecular cell 1 (3), 359-369, 1998 | 504 | 1998 |