| Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27 M Pagano, SW Tam, AM Theodoras, P Beer-Romero, G Del Sal, V Chau, ... Science 269 (5224), 682-685, 1995 | 2315 | 1995 |
| Cyclin D1 is a nuclear protein required for cell cycle progression in G1. V Baldin, J Lukas, MJ Marcote, M Pagano, G Draetta Genes & development 7 (5), 812-821, 1993 | 2148 | 1993 |
| Cyclin A is required at two points in the human cell cycle. M Pagano, R Pepperkok, F Verde, W Ansorge, G Draetta The EMBO journal 11 (3), 961-971, 1992 | 1799 | 1992 |
| Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas M Loda, B Cukor, SW Tam, P Lavin, M Fiorentinc, GF Draetta, JM Jessup, ... Nature medicine 3 (2), 231-234, 1997 | 1398 | 1997 |
| Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function A Viale, P Pettazzoni, CA Lyssiotis, H Ying, N Sánchez, M Marchesini, ... Nature 514 (7524), 628-632, 2014 | 1275 | 2014 |
| Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement G Draetta, D Beach Cell 54 (1), 17-26, 1988 | 965 | 1988 |
| Phosphorylation and activation of human cdc25‐C by cdc2‐‐cyclin B and its involvement in the self‐amplification of MPF at mitosis. I Hoffmann, PR Clarke, MJ Marcote, E Karsenti, G Draetta The EMBO journal 12 (1), 53-63, 1993 | 901 | 1993 |
| An inhibitor of oxidative phosphorylation exploits cancer vulnerability JR Molina, Y Sun, M Protopopova, S Gera, M Bandi, C Bristow, T McAfoos, ... Nature medicine 24 (7), 1036-1046, 2018 | 842 | 2018 |
| Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF G Draetta, F Luca, J Westendorf, L Brizuela, J Ruderman, D Beach Cell 56 (5), 829-838, 1989 | 833 | 1989 |
| FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors J O'Neil, J Grim, P Strack, S Rao, D Tibbitts, C Winter, J Hardwick, ... Journal of Experimental Medicine 204 (8), 1813-1824, 2007 | 820 | 2007 |
| Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer A Kapoor, W Yao, H Ying, S Hua, A Liewen, Q Wang, Y Zhong, CJ Wu, ... Cell 158 (1), 185-197, 2014 | 766 | 2014 |
| Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation A Montagnoli, F Fiore, E Eytan, AC Carrano, GF Draetta, A Hershko, ... Genes & development 13 (9), 1181-1189, 1999 | 752 | 1999 |
| CDC25 phosphatases as potential human oncogenes K Galaktionov, AK Lee, J Eckstein, G Draetta, J Meckler, M Loda, D Beach Science 269 (5230), 1575-1577, 1995 | 674 | 1995 |
| Activation of the phosphatase activity of human cdc25A by a cdk2‐cyclin E dependent phosphorylation at the G1/S transition. I Hoffmann, G Draetta, E Karsenti The EMBO journal 13 (18), 4302-4310, 1994 | 652 | 1994 |
| Regulating mammalian checkpoints through Cdc25 inactivation M Donzelli, GF Draetta EMBO reports 4 (7), 671-677, 2003 | 651 | 2003 |
| Genetics and biology of pancreatic ductal adenocarcinoma H Ying, P Dey, W Yao, AC Kimmelman, GF Draetta, A Maitra, RA DePinho Genes & development 30 (4), 355-385, 2016 | 611 | 2016 |
| SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins L Busino, F Bassermann, A Maiolica, C Lee, PM Nolan, SIH Godinho, ... science 316 (5826), 900-904, 2007 | 610 | 2007 |
| Calcineurin CB Klee, GF Draetta, MJ Hubbard Advances in enzymology and related areas of molecular biology 61, 149-200, 1988 | 584 | 1988 |
| Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage L Busino, M Donzelli, M Chiesa, D Guardavaccaro, D Ganoth, ... Nature 426 (6962), 87-91, 2003 | 565 | 2003 |
| Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis AO Morla, G Draetta, D Beach, JYJ Wang Cell 58 (1), 193-203, 1989 | 546 | 1989 |
