دنبال کردن
Deniz Dalkara
Deniz Dalkara
1 INSERM, U968, Paris, F-75012, France; 2 Sorbonne Universités, UPMC Univ Paris 06, UMR_S 968
ایمیل تأیید شده در inserm.fr
عنوان
نقل شده توسط
نقل شده توسط
سال
In vivo–directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous‏
D Dalkara, LC Byrne, RR Klimczak, M Visel, L Yin, WH Merigan, ...‏
Science translational medicine 5 (189), 189ra76-189ra76, 2013‏
8162013
Partial recovery of visual function in a blind patient after optogenetic therapy‏
JA Sahel, E Boulanger-Scemama, C Pagot, A Arleo, F Galluppi, JN Martel, ...‏
Nature medicine 27 (7), 1223-1229, 2021‏
5862021
Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis‏
N Aït-Ali, R Fridlich, G Millet-Puel, E Clérin, F Delalande, C Jaillard, ...‏
Cell 161 (4), 817-832, 2015‏
4102015
Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous‏
D Dalkara, KD Kolstad, N Caporale, M Visel, RR Klimczak, DV Schaffer, ...‏
Molecular Therapy 17 (12), 2096-2102, 2009‏
3802009
Emerging therapies for inherited retinal degeneration‏
HPN Scholl, RW Strauss, MS Singh, D Dalkara, B Roska, S Picaud, ...‏
Science translational medicine 8 (368), 368rv6-368rv6, 2016‏
2492016
A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells‏
RR Klimczak, JT Koerber, D Dalkara, JG Flannery, DV Schaffer‏
PloS one 4 (10), e7467, 2009‏
2422009
Intravitreal injection of AAV2 transduces macaque inner retina‏
L Yin, K Greenberg, JJ Hunter, D Dalkara, KD Kolstad, BD Masella, ...‏
Investigative ophthalmology & visual science 52 (5), 2775-2783, 2011‏
2212011
Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV restores ON and OFF visual responses in blind mice‏
E Macé, R Caplette, O Marre, A Sengupta, A Chaffiol, P Barbe, ...‏
Molecular Therapy 23 (1), 7-16, 2015‏
2202015
Molecular evolution of adeno-associated virus for enhanced glial gene delivery‏
JT Koerber, R Klimczak, JH Jang, D Dalkara, JG Flannery, DV Schaffer‏
Molecular Therapy 17 (12), 2088-2095, 2009‏
2192009
LiGluR restores visual responses in rodent models of inherited blindness‏
N Caporale, KD Kolstad, T Lee, I Tochitsky, D Dalkara, D Trauner, ...‏
Molecular therapy 19 (7), 1212-1219, 2011‏
2032011
Rapid optical control of nociception with an ion-channel photoswitch‏
A Mourot, T Fehrentz, Y Le Feuvre, CM Smith, C Herold, D Dalkara, ...‏
Nature methods 9 (4), 396-402, 2012‏
1992012
Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration‏
LC Byrne, D Dalkara, G Luna, SK Fisher, E Clérin, JA Sahel, T Léveillard, ...‏
The Journal of clinical investigation 125 (1), 105-116, 2015‏
1982015
Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina‏
A Sengupta, A Chaffiol, E Macé, R Caplette, M Desrosiers, M Lampič, ...‏
EMBO molecular medicine 8 (11), 1248-1264, 2016‏
1902016
Let there be light: gene and cell therapy for blindness‏
D Dalkara, O Goureau, K Marazova, JA Sahel‏
Human gene therapy 27 (2), 134-147, 2016‏
1592016
A new promoter allows optogenetic vision restoration with enhanced sensitivity in macaque retina‏
A Chaffiol, R Caplette, C Jaillard, E Brazhnikova, M Desrosiers, E Dubus, ...‏
Molecular Therapy 25 (11), 2546-2560, 2017‏
1572017
Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve‏
V Pernet, S Joly, D Dalkara, N Jordi, O Schwarz, F Christ, DV Schaffer, ...‏
Neurobiology of disease 51, 202-213, 2013‏
1522013
Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve‏
V Pernet, S Joly, N Jordi, D Dalkara, A Guzik-Kornacka, JG Flannery, ...‏
Cell death & disease 4 (7), e734-e734, 2013‏
1362013
Vertebrate cone opsins enable sustained and highly sensitive rapid control of Gi/o signaling in anxiety circuitry‏
OA Masseck, K Spoida, D Dalkara, T Maejima, JM Rubelowski, ...‏
Neuron 81 (6), 1263-1273, 2014‏
1352014
AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa‏
D Dalkara, KD Kolstad, KI Guerin, NV Hoffmann, M Visel, RR Klimczak, ...‏
Molecular Therapy 19 (9), 1602-1608, 2011‏
1322011
Early and late stage gene therapy interventions for inherited retinal degenerations‏
C Botto, M Rucli, MD Tekinsoy, J Pulman, JA Sahel, D Dalkara‏
Progress in Retinal and Eye Research 86, 100975, 2022‏
1282022
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مقاله‌ها 1–20