| Comparative genomics of the eukaryotes GM Rubin, MD Yandell, JR Wortman, GL Gabor, Miklos, CR Nelson, ... Science 287 (5461), 2204-2215, 2000 | 2205 | 2000 |
| Insights into social insects from the genome of the honeybee Apis mellifera Honeybee Genome Sequencing Consortium Nature 443 (7114), 931, 2006 | 2073* | 2006 |
| Ion channels and synaptic organization: analysis of the Drosophila genome JT Littleton, B Ganetzky Neuron 26 (1), 35-43, 2000 | 621 | 2000 |
| Mutational analysis of Drosophila synaptotagmin demonstrates its essential role in Ca2+-activated neurotransmitter release JT Littleton, M Stern, K Schulze, M Perin, HJ Bellen Cell 74 (6), 1125-1134, 1993 | 560 | 1993 |
| A Drosophila neurexin is required for septate junction and blood-nerve barrier formation and function S Baumgartner, JT Littleton, K Broadie, MA Bhat, R Harbecke, JA Lengyel, ... Cell 87 (6), 1059-1068, 1996 | 494 | 1996 |
| Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease WCM Lee, M Yoshihara, JT Littleton Proceedings of the National Academy of Sciences 101 (9), 3224-3229, 2004 | 404 | 2004 |
| Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants. JT Littleton, M Stern, M Perin, HJ Bellen Proceedings of the National Academy of Sciences 91 (23), 10888-10892, 1994 | 350 | 1994 |
| Synaptotagmin I functions as a calcium sensor to synchronize neurotransmitter release M Yoshihara, JT Littleton Neuron 36 (5), 897-908, 2002 | 349 | 2002 |
| The biological function of the Huntingtin protein and its relevance to Huntington’s Disease pathology J Schulte, JT Littleton Current trends in neurology 5, 65, 2011 | 322 | 2011 |
| A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth S Huntwork, JT Littleton Nature neuroscience 10 (10), 1235-1237, 2007 | 313 | 2007 |
| Expression of Synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapse JT Littleton, HJ Bellen, MS Perin Development 118 (4), 1077-1088, 1993 | 298 | 1993 |
| Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission. K Broadie, HJ Bellen, A DiAntonio, JT Littleton, TL Schwarz Proceedings of the National Academy of Sciences 91 (22), 10727-10731, 1994 | 271 | 1994 |
| Temperature-sensitive paralytic mutations demonstrate that synaptic exocytosis requires SNARE complex assembly and disassembly JT Littleton, ER Chapman, R Kreber, MB Garment, SD Carlson, ... Neuron 21 (2), 401-413, 1998 | 268 | 1998 |
| ROP, the Drosophila Sec1 homolog, interacts with syntaxin and regulates neurotransmitter release in a dosage‐dependent manner MN Wu, JT Littleton, MA Bhat, A Prokop, HJ Bellen The EMBO journal, 1998 | 237 | 1998 |
| synaptotagmin mutants reveal essential functions for the C2B domain in Ca2+-triggered fusion and recycling of synaptic vesicles in vivo JT Littleton, J Bai, B Vyas, R Desai, AE Baltus, MB Garment, SD Carlson, ... Journal of Neuroscience 21 (5), 1421-1433, 2001 | 228 | 2001 |
| Rop, a Drosophila homolog of yeast Sec1 and vertebrate n-Sect/Munc-18 proteins, is a negative regulator of neurotransmitter release in vivo KL Schulze, JT Littleton, A Salzberg, N Halachmi, M Stern, Z Lev, ... Neuron 13 (5), 1099-1108, 1994 | 220 | 1994 |
| Spontaneous and evoked release are independently regulated at individual active zones JE Melom, Y Akbergenova, JP Gavornik, JT Littleton Journal of Neuroscience 33 (44), 17253-17263, 2013 | 211 | 2013 |
| Synaptotagmin controls and modulates synaptic-vesicle fusion in a Ca2+-dependent manner JT Littleton, HJ Bellen Trends in neurosciences 18 (4), 177-183, 1995 | 206 | 1995 |
| Transmission, development, and plasticity of synapses KP Harris, JT Littleton Genetics 201 (2), 345-375, 2015 | 205 | 2015 |
| Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila IP Coyle, YH Koh, WCM Lee, J Slind, T Fergestad, JT Littleton, ... Neuron 41 (4), 521-534, 2004 | 200 | 2004 |