Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses D Wang, H Mou, S Li, Y Li, S Hough, K Tran, J Li, H Yin, DG Anderson, ... Human gene therapy 26 (7), 432-442, 2015 | 419 | 2015 |
Global CNS transduction of adult mice by intravenously delivered rAAVrh. 8 and rAAVrh. 10 and nonhuman primates by rAAVrh. 10 B Yang, S Li, H Wang, Y Guo, DJ Gessler, C Cao, Q Su, J Kramer, ... Molecular Therapy 22 (7), 1299-1309, 2014 | 267 | 2014 |
Empty virions in AAV8 vector preparations reduce transduction efficiency and may cause total viral particle dose-limiting side effects K Gao, M Li, L Zhong, Q Su, J Li, S Li, R He, Y Zhang, G Hendricks, ... Molecular Therapy Methods & Clinical Development 1, 2014 | 169 | 2014 |
Tissue transglutaminase does not affect fibrotic matrix stability or regression of liver fibrosis in mice Y Popov, DY Sverdlov, AK Sharma, KR Bhaskar, S Li, TL Freitag, J Lee, ... Gastroenterology 140 (5), 1642-1652, 2011 | 165 | 2011 |
HIV and HCV cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and NFκB W Lin, G Wu, S Li, EM Weinberg, K Kumthip, LF Peng, J Méndez-Navarro, ... Journal of Biological Chemistry 286 (4), 2665-2674, 2011 | 131 | 2011 |
Efficient and targeted transduction of nonhuman primate liver with systemically delivered optimized AAV3B vectors S Li, C Ling, L Zhong, M Li, Q Su, R He, Q Tang, DL Greiner, LD Shultz, ... Molecular Therapy 23 (12), 1867-1876, 2015 | 117 | 2015 |
A rationally engineered capsid variant of AAV9 for systemic CNS-directed and peripheral tissue-detargeted gene delivery in neonates D Wang, S Li, DJ Gessler, J Xie, L Zhong, J Li, K Tran, K Van Vliet, L Ren, ... Molecular Therapy Methods & Clinical Development 9, 234-246, 2018 | 74 | 2018 |
Large-scale production of adeno-associated viral vector serotype-9 carrying the human survival motor neuron gene A Rashnonejad, GA Chermahini, S Li, F Ozkinay, G Gao Molecular biotechnology 58, 30-36, 2016 | 54 | 2016 |
Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction L Zhong, N Malani, M Li, T Brady, J Xie, P Bell, S Li, H Jones, JM Wilson, ... Human gene therapy 24 (5), 520-525, 2013 | 53 | 2013 |
Recombinant AAV vectors useful for reducing immunity against transgene products G Gao, PD Zamore, S Li US Patent 10,975,391, 2021 | 52 | 2021 |
Yak interferon-alpha loaded solid lipid nanoparticles for controlled release S Li, B Zhao, F Wang, M Wang, S Xie, S Wang, C Han, L Zhu, W Zhou Research in veterinary science 88 (1), 148-153, 2010 | 45 | 2010 |
Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity Y Xiao, M Muhuri, S Li, W Qin, G Xu, L Luo, J Li, AJ Letizia, SK Wang, ... JCI insight 4 (13), e99052, 2019 | 43 | 2019 |
Hepatitis c virus‐specific t‐cell‐derived transforming growth factor beta is associated with slow hepatic fibrogenesis S Li, LEM Vriend, IA Nasser, Y Popov, NH Afdhal, MJ Koziel, D Schuppan, ... Hepatology 56 (6), 2094-2105, 2012 | 34 | 2012 |
Evidence for the existence of paraflagellar rod protein 2 (PFR2) gene in Trypanosoma evansi and its conservation among other kinetoplastid parasites MH Abdille, SY Li, Y Jia, X Suo, G Mkoji Experimental parasitology 118 (4), 614-618, 2008 | 18 | 2008 |
Trypanosoma evansi: Paraflagellar rod protein 1 and 2 are similar but lack common B cell epitopes MH Abdille, SY Li, J Ding, X Suo Experimental parasitology 120 (4), 411-416, 2008 | 14 | 2008 |
Vector sequences are not detected in tumor tissue from research subjects with ornithine transcarbamylase deficiency who previously received adenovirus gene transfer L Zhong, S Li, M Li, J Xie, Y Zhang, B Lee, ML Batshaw, JM Wilson, G Gao Human Gene Therapy 24 (9), 814-819, 2013 | 5 | 2013 |
RNA-driven evolution of AAV capsid libraries identifies variants with High transduction efficiency in non-human primate central nervous system M Nonnenmacher, S Li, W Wang, MA Child, AZ Ren, K Tyson, N Pande, ... MOLECULAR THERAPY 29 (4), 25-26, 2021 | 2 | 2021 |
AAV capsids with increased tropism to brain tissue ME Nonnenmacher, J Hou, W Wang, M Child, S Li US Patent 11,859,200, 2024 | 1 | 2024 |
Redirection of tropism of aav capsids ME Nonnenmacher, J Hou, W Wang, M Child, S Li US Patent App. 17/924,800, 2023 | 1 | 2023 |
Intravenous Delivery of AAV Gene Therapy Provides Broad SOD1 Knockdown in the Spinal Cord and Robust Efficacy in a Mouse Model of SOD1-ALS MD Grannan, A Sayed-Zahid, M Hefferan, M Nonnenmacher, SLK Grant, ... MOLECULAR THERAPY 30 (4), 495-495, 2022 | | 2022 |