NAD (H) and NADP (H) redox couples and cellular energy metabolism W Xiao, RS Wang, DE Handy, J Loscalzo Antioxidants & Redox Signaling 28 (3), 251-272, 2018 | 830 | 2018 |
Boolean modeling in systems biology: an overview of methodology and applications RS Wang, A Saadatpour, R Albert Physical Biology 9 (5), 055001, 2012 | 568 | 2012 |
Network-based approach to prediction and population-based validation of in silico drug repurposing F Cheng, RJ Desai, DE Handy, RS Wang, S Schneeweiss, AL Barabási, ... Nature Communications 9 (1), 2691, 2018 | 531 | 2018 |
Border control—a membrane-linked interactome of Arabidopsis AM Jones, Y Xuan, M Xu, RS Wang, CH Ho, S Lalonde, CH You, MI Sardi, ... Science 344 (6185), 711-716, 2014 | 242 | 2014 |
Dynamical and structural analysis of a T cell survival network identifies novel candidate therapeutic targets for large granular lymphocyte leukemia A Saadatpour, RS Wang, A Liao, X Liu, TP Loughran, I Albert, R Albert PLoS Computational Biology 7 (11), e1002267, 2011 | 235 | 2011 |
Common and unique elements of the ABA-regulated transcriptome of Arabidopsis guard cells RS Wang, S Pandey, S Li, TE Gookin, Z Zhao, R Albert, SM Assmann BMC genomics 12 (1), 1-24, 2011 | 224 | 2011 |
A genome-wide positioning systems network algorithm for in silico drug repurposing F Cheng, W Lu, C Liu, J Fang, Y Hou, DE Handy, RS Wang, Y Zhao, ... Nature Communications 10 (1), 3476, 2019 | 205 | 2019 |
Comprehensive characterization of protein–protein interactions perturbed by disease mutations F Cheng, J Zhao, Y Wang, W Lu, Z Liu, Y Zhou, WR Martin, RS Wang, ... Nature Genetics 53 (3), 342-353, 2021 | 181 | 2021 |
Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G‐protein action S Pandey*, RS Wang*, L Wilson, S Li, Z Zhao, TE Gookin, SM Assmann, ... Molecular Systems Biology 6 (1), 372, 2010 | 156 | 2010 |
NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension AO Samokhin, T Stephens, BM Wertheim, RS Wang, SO Vargas, LM Yung, ... Science Translational Medicine 10 (445), eaap7294, 2018 | 123 | 2018 |
Abscisic Acid–Responsive Guard Cell Metabolomes of Arabidopsis Wild-Type and gpa1 G-Protein Mutants X Jin, RS Wang, M Zhu, BW Jeon, R Albert, S Chen, SM Assmann The Plant Cell, 25: 4789-4811, 2013 | 100 | 2013 |
Immunoglobulin-driven complement activation regulates proinflammatory remodeling in pulmonary hypertension MG Frid, BA McKeon, JM Thurman, BA Maron, M Li, H Zhang, S Kumar, ... American Journal of Respiratory and Critical Care Medicine 201 (2), 224-239, 2020 | 93 | 2020 |
Endophenotype network models: common core of complex diseases SD Ghiassian, J Menche, DI Chasman, F Giulianini, RS Wang, ... Scientific Reports 6 (1), 27414, 2016 | 92 | 2016 |
Systems medicine: evolution of systems biology from bench to bedside RS Wang, BA Maron, J Loscalzo Wiley Interdisciplinary Reviews: Systems Biology and Medicine 7 (4), 141-161, 2015 | 92 | 2015 |
Elementary signaling modes predict the essentiality of signal transduction network components RS Wang, R Albert BMC Systems Biology 5 (1), 44, 2011 | 92 | 2011 |
Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery P Paci, G Fiscon, F Conte, RS Wang, L Farina, J Loscalzo NPJ systems biology and applications 7 (1), 3, 2021 | 90 | 2021 |
Individualized interactomes for network-based precision medicine in hypertrophic cardiomyopathy with implications for other clinical pathophenotypes BA Maron*, RS Wang*, S Shevtsov, SG Drakos, E Arons, O Wever-Pinzon, ... Nature Communications 12, 873, 2021 | 75 | 2021 |
Interferon-gamma Impairs Human Coronary Artery Endothelial Glucose Metabolism via Tryptophan Catabolism and Activates Fatty Acid Oxidation LYH Lee, WM Oldham, H He, RS Wang, R Mulhern, DE Handy, ... Circulation 144, 1612–1628, 2021 | 64 | 2021 |
Network-based disease module discovery by a novel seed connector algorithm with pathobiological implications RS Wang, J Loscalzo Journal of Molecular Biology 430 (18), 2939-2950, 2018 | 59 | 2018 |
Two-stage flux balance analysis of metabolic networks for drug target identification Z Li, RS Wang, XS Zhang BMC Systems Biology 5 (1), S11, 2011 | 56 | 2011 |