| Transcriptional regulatory networks underlying gene expression changes in Huntington's disease SA Ament, JR Pearl, JP Cantle, RM Bragg, PJ Skene, SR Coffey, ... Molecular systems biology 14 (3), e7435, 2018 | 76 | 2018 |
| Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington’s disease RM Bragg, SR Coffey, RM Weston, SA Ament, JP Cantle, S Minnig, ... Scientific reports 7 (1), 41570, 2017 | 23 | 2017 |
| Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington’s disease SR Coffey, RM Bragg, S Minnig, SA Ament, JP Cantle, A Glickenhaus, ... PloS one 12 (4), e0175968, 2017 | 17 | 2017 |
| Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools S Minnig, RM Bragg, HS Tiwana, WT Solem, WS Hovander, EMS Vik, ... Scientific Reports 8 (1), 2304, 2018 | 7 | 2018 |
| Huntingtin lowering reduces somatic instability at CAG-expanded loci SR Coffey, M Andrew, H Ging, J Hamilton, M Flower, M Kovalenko, ... bioRxiv, 2020.07. 23.218347, 2020 | 5 | 2020 |
| Altered Huntingtin-Chromatin Interactions Predict Transcriptional and Epigenetic Changes in Huntington’s Disease Mouse Models JR Pearl, AC Shetty, JP Cantle, DE Bergey, RM Bragg, SR Coffey, ... bioRxiv, 2020.06. 04.132571, 2020 | 5 | 2020 |
| Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation RM Bragg, SR Coffey, JP Cantle, S Hu, S Singh, SRW Legg, CA McHugh, ... Life Science Alliance 6 (11), 2023 | 3 | 2023 |
| Suppression of Huntington’s Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding EW Mathews, SR Coffey, A Gärtner, J Belgrad, RM Bragg, D O’Reilly, ... bioRxiv, 2024 | 2 | 2024 |
| Global huntingtin knockout in adult mice leads to fatal neurodegeneration that spares the pancreas RM Bragg, EW Mathews, A Grindeland, JP Cantle, D Howland, T Vogt, ... Life Science Alliance 7 (9), 2024 | 1 | 2024 |
| Hereditary spastic paraplegia with thin corpus callosum and SPG11 mutation: A neuropathological evaluation KP Scherpelz, RA Yoda, S Jayadev, MY Davis, JC Hincks, NF Liachko, ... Neuropathology, 2024 | | 2024 |
| A011 Blocking Huntingtin’s transcription protects against somatic instability E Mathews, S Coffey, R Bragg, J Cantle, C McHugh, A Gaertner, J Fentz, ... Journal of Neurology, Neurosurgery & Psychiatry 95 (Suppl 1), A4-A4, 2024 | | 2024 |
| A016 Protein-protein interaction networks identify a role for Huntingtin in regulating chromatin organization and cell identity J Cantle, R Bragg, E Mathews, T Greco, S Coffey, J Simen, K Wright, ... Journal of Neurology, Neurosurgery & Psychiatry 95 (Suppl 1), A6-A6, 2024 | | 2024 |
Jeff CarrollAssociate Professor, Department of Neurology, University of Washingtonایمیل تأیید شده در uw.edu