In Vivo Selection for Formate Dehydrogenases with High Efficiency and Specificity toward NADP+ L Calzadiaz-Ramirez, C Calvó-Tusell, GMM Stoffel, SN Lindner, S Osuna, ... ACS catalysis 10 (14), 7512-7525, 2020 | 77 | 2020 |
Dual-function enzyme catalysis for enantioselective carbon–nitrogen bond formation Z Liu, C Calvó-Tusell, AZ Zhou, K Chen, M Garcia-Borràs, FH Arnold Nature Chemistry 13 (12), 1166-1172, 2021 | 63 | 2021 |
Discovery and in vivo proof of concept of a highly potent dual inhibitor of soluble epoxide hydrolase and acetylcholinesterase for the treatment of Alzheimer’s disease S Codony, C Pont, C Griñán-Ferré, A Di Pede-Mattatelli, C Calvó-Tusell, ... Journal of Medicinal Chemistry 65 (6), 4909-4925, 2022 | 38 | 2022 |
Time evolution of the millisecond allosteric activation of imidazole glycerol phosphate synthase C Calvó-Tusell, MA Maria-Solano, S Osuna, F Feixas Journal of the American Chemical Society 144 (16), 7146-7159, 2022 | 31 | 2022 |
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis S Codony, C Calvó-Tusell, E Valverde, S Osuna, C Morisseau, MI Loza, ... Journal of medicinal chemistry 64 (9), 5429-5446, 2021 | 22 | 2021 |
Reversing the Enantioselectivity of Enzymatic Carbene N− H Insertion Through Mechanism‐Guided Protein Engineering C Calvó‐Tusell, Z Liu, K Chen, FH Arnold, M Garcia‐Borràs Angewandte Chemie 135 (35), e202303879, 2023 | 12 | 2023 |
Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors S Codony, JM Entrena, C Calvó-Tusell, B Jora, R González-Cano, ... Journal of medicinal chemistry 65 (20), 13660-13680, 2022 | 7 | 2022 |
Biocatalytic desymmetrization for synthesis of chiral enones using flavoenzymes QQ Zeng, QY Zhou, C Calvó-Tusell, SY Dai, X Zhao, M Garcia-Borràs, ... Nature Synthesis, 1-9, 2024 | 2 | 2024 |
Unravelling the Graded Millisecond Allosteric Activation Mechanism of Imidazole Glycerol Phosphate Synthase C Calvó-Tusell, MA Maria-Solano, S Osuna, F Feixas bioRxiv, 2021.10. 21.464958, 2021 | 1 | 2021 |
A new family of soluble epoxide hydrolase inhibitors: in vivo evaluation in a murine model of chemotherapy-induced neuropathic pain S Vázquez, S Codony, B Jora, AL Turcu, C Calvó-Tusell, C Morisseau, ... | | 2023 |
Computational strategies for understanding the molecular basis of biochemical and biocatalytic processes C Calvó-Tusell Universitat de Girona, 2023 | | 2023 |
In vivo evaluation of soluble epoxide hydrolase inhibitors in murine models of allodynia, chemotherapy-induced neuropathic pain and visceral pain S Vázquez, S Codony, B Jora, JM Entrena, M Santos-Caballero, AL Turcu, ... | | 2023 |
Marc Garcia-Borràs C Calvó-Tusell, Z Liu, K Chen, FH Arnold Angew. Chem. Int. Ed, e202303879, 2023 | | 2023 |
Supporting information Discovery and in Vivo Proof-of-Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of … S Codony, C Pont, C Griñán-Ferré, D Pede-Mattatelli, C Calvó-Tusell, ... American Chemical Society, 2022 | | 2022 |
Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease S Codony Gisbert, C Pont Masanet, C Griñán Ferré, D Pede-Mattatelli, ... Journal of Medicinal Chemistry, 2022, vol. 65, num. 6, p. 4909-4925, 2022 | | 2022 |