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Jason R. Spence
Jason R. Spence
Dirección de correo verificada de umich.edu - Página principal
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SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ...
Cell 181 (5), 1016-1035. e19, 2020
25052020
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
JR Spence, CN Mayhew, SA Rankin, MF Kuhar, JE Vallance, K Tolle, ...
Nature 470 (7332), 105-109, 2011
21272011
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
KW McCracken, EM Catá, CM Crawford, KL Sinagoga, M Schumacher, ...
Nature 516 (7531), 400-404, 2014
10802014
In vitro generation of human pluripotent stem cell derived lung organoids
BR Dye, DR Hill, MAH Ferguson, YH Tsai, MS Nagy, R Dyal, JM Wells, ...
elife 4, e05098, 2015
8442015
An in vivo model of human small intestine using pluripotent stem cells
CL Watson, MM Mahe, J Múnera, JC Howell, N Sundaram, HM Poling, ...
Nature medicine 20 (11), 1310-1314, 2014
6132014
Synthetic hydrogels for human intestinal organoid generation and colonic wound repair
R Cruz-Acuña, M Quirós, AE Farkas, PH Dedhia, S Huang, D Siuda, ...
Nature cell biology 19 (11), 1326-1335, 2017
5182017
Facile isolation and the characterization of human retinal stem cells
BLK Coles, B Angénieux, T Inoue, K Del Rio-Tsonis, JR Spence, ...
Proceedings of the National Academy of Sciences 101 (44), 15772-15777, 2004
5152004
Generating human intestinal tissue from pluripotent stem cells in vitro
KW McCracken, JC Howell, JM Wells, JR Spence
Nature protocols 6 (12), 1920-1928, 2011
4852011
Sox17 and Sox4 differentially regulate β-catenin/T-cell factor activity and proliferation of colon carcinoma cells
D Sinner, JJ Kordich, JR Spence, R Opoka, S Rankin, SCJ Lin, D Jonatan, ...
Molecular and cellular biology 27 (22), 7802-7815, 2007
3902007
Generation of lung organoids from human pluripotent stem cells in vitro
AJ Miller, BR Dye, D Ferrer-Torres, DR Hill, AW Overeem, LD Shea, ...
Nature protocols 14 (2), 518-540, 2019
3872019
Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function
JL Leslie, S Huang, JS Opp, MS Nagy, M Kobayashi, VB Young, ...
Infection and immunity 83 (1), 138-145, 2015
3572015
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells
JR Spence, AW Lange, SCJ Lin, KH Kaestner, AM Lowy, I Kim, ...
Developmental cell 17 (1), 62-74, 2009
3542009
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19
JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ...
Immunity 53 (6), 1296-1314. e9, 2020
3382020
Organoid models of human gastrointestinal development and disease
PH Dedhia, N Bertaux-Skeirik, Y Zavros, JR Spence
Gastroenterology 150 (5), 1098-1112, 2016
2962016
Sox9 plays multiple roles in the lung epithelium during branching morphogenesis
BE Rockich, SM Hrycaj, HP Shih, MS Nagy, MAH Ferguson, JL Kopp, ...
Proceedings of the National Academy of Sciences 110 (47), E4456-E4464, 2013
2942013
Differentiation of human pluripotent stem cells into colonic organoids via transient activation of BMP signaling
JO Múnera, N Sundaram, SA Rankin, D Hill, C Watson, M Mahe, ...
Cell stem cell 21 (1), 51-64. e6, 2017
2722017
Vertebrate intestinal endoderm development
JR Spence, R Lauf, NF Shroyer
Developmental dynamics 240 (3), 501-520, 2011
2492011
Transcriptome-wide analysis reveals hallmarks of human intestine development and maturation in vitro and in vivo
SR Finkbeiner, DR Hill, CH Altheim, PH Dedhia, MJ Taylor, YH Tsai, ...
Stem cell reports 4 (6), 1140-1155, 2015
2482015
Microbial metabolite signaling is required for systemic iron homeostasis
NK Das, AJ Schwartz, G Barthel, N Inohara, Q Liu, A Sankar, DR Hill, ...
Cell metabolism 31 (1), 115-130. e6, 2020
2452020
Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche
Y Shao, K Taniguchi, K Gurdziel, RF Townshend, X Xue, KMA Yong, ...
Nature materials 16 (4), 419-425, 2017
2412017
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