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Dustin Middleton
Dustin Middleton
Duke University Medical Center
Dirección de correo verificada de duke.edu
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Carbohydrates as T-cell antigens with implications in health and disease
L Sun, DR Middleton, PL Wantuch, A Ozdilek, FY Avci
Glycobiology 26 (10), 1029-1040, 2016
922016
Genotypic and phenotypic diversity among human isolates of Akkermansia muciniphila
B Becken, L Davey, DR Middleton, KD Mueller, A Sharma, ZC Holmes, ...
MBio 12 (3), 10.1128/mbio. 00478-21, 2021
742021
Rapid screening of sugar-nucleotide donor specificities of putative glycosyltransferases
MO Sheikh, SM Halmo, S Patel, D Middleton, H Takeuchi, CM Schafer, ...
Glycobiology 27 (3), 206-212, 2017
512017
T cell–mediated humoral immune responses to type 3 capsular polysaccharide of Streptococcus pneumoniae
DR Middleton, L Sun, AV Paschall, FY Avci
The Journal of Immunology 199 (2), 598-603, 2017
402017
Enzymatic hydrolysis of pneumococcal capsular polysaccharide renders the bacterium vulnerable to host defense
DR Middleton, AV Paschall, JA Duke, FY Avci
Infection and immunity 86 (8), 10.1128/iai. 00316-18, 2018
252018
Opsonophagocytic killing assay to assess immunological responses against bacterial pathogens
AV Paschall, DR Middleton, FY Avci
Journal of visualized experiments: JoVE, 10.3791/59400, 2019
242019
Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help
L Sun, AV Paschall, DR Middleton, M Ishihara, A Ozdilek, PL Wantuch, ...
Nature Communications 11 (1), 2550, 2020
212020
Identification and characterization of the Streptococcus pneumoniae type 3 capsule-specific glycoside hydrolase of Paenibacillus species 32352
DR Middleton, X Zhang, PL Wantuch, A Ozdilek, X Liu, R LoPilato, ...
Glycobiology 28 (2), 90-99, 2018
192018
Profiling pneumococcal type 3-derived oligosaccharides by high resolution liquid chromatography–tandem mass spectrometry
G Li, L Li, C Xue, D Middleton, RJ Linhardt, FY Avci
Journal of Chromatography A 1397, 43-51, 2015
162015
Glycoconjugate synthesis using chemoselective ligation
S Cheng, PL Wantuch, ME Kizer, DR Middleton, R Wang, M DiBello, M Li, ...
Organic & biomolecular chemistry 17 (10), 2646-2650, 2019
142019
Glycosyltransferases within the psrP Locus Facilitate Pneumococcal Virulence
DR Middleton, J Aceil, S Mustafa, AV Paschall, FY Avci
Journal of Bacteriology 203 (7), 10.1128/jb. 00389-20, 2021
112021
Metabolic labeling of HIV-1 envelope glycoprotein gp120 to elucidate the effect of gp120 glycosylation on antigen uptake
L Sun, M Ishihara, DR Middleton, M Tiemeyer, FY Avci
Journal of Biological Chemistry 293 (39), 15178-15194, 2018
112018
A structural model for the ligand binding of pneumococcal serotype 3 capsular polysaccharide-specific protective antibodies
A Ozdilek, J Huang, R Babb, AV Paschall, DR Middleton, JA Duke, ...
MBio 12 (3), 10.1128/mbio. 00800-21, 2021
102021
Genotypic and phenotypic diversity among human isolates of Akkermansia muciniphila. mBio 12: e00478-21
B Becken, L Davey, DR Middleton, KD Mueller, A Sharma, ZC Holmes, ...
72021
Complete genome sequence of the bacterium Bacillus circulans Jordan strain 32352
DR Middleton, W Lorenz, FY Avci
Genome Announcements 5 (19), 10.1128/genomea. 00289-17, 2017
62017
Complex glycans and immune regulation
AV Paschall, DR Middleton, FY Avci
Academic Press, 2023
52023
Therapeutic Activity of Type 3 Streptococcus pneumoniae Capsule Degrading Enzyme Pn3Pase
AV Paschall, DR Middleton, PL Wantuch, FY Avci
Pharmaceutical Research 37, 1-9, 2020
32020
Proteins having pneumococcal capsule degrading activity and methods of use
FY Avci, D Middleton, AV Paschall
US Patent App. 18/199,685, 2024
2024
Proteins having pneumococcal capsule degrading activity and methods of use
FY Avci, D Middleton, AV Paschall
US Patent 11,690,900, 2023
2023
Exploiting Glycans in Vaccine Design
DR Middleton, FY Avci
2022
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