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Christopher J Squire
Christopher J Squire
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Structure of the first parallel DNA quadruplex-drug complex
GR Clark, PD Pytel, CJ Squire, S Neidle
Journal of the American Chemical Society 125 (14), 4066-4067, 2003
2852003
Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis
N Koon, CJ Squire, EN Baker
Proceedings of the National Academy of Sciences 101 (22), 8295-8300, 2004
1572004
Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed
Y Yosaatmadja, S Silva, JM Dickson, AV Patterson, JB Smaill, ...
Journal of structural biology 192 (3), 539-544, 2015
1402015
Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypicaltyrosine kinase with a key role in CDK1 regulation
CJ Squire, JM Dickson, I Ivanovic, EN Baker
Structure 13 (4), 541-550, 2005
1302005
Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of …
G Bashiri, CJ Squire, NJ Moreland, EN Baker
Journal of Biological Chemistry 283 (25), 17531-17541, 2008
1162008
Trapping HIV-1 reverse transcriptase before and after translocation on DNA
SG Sarafianos, AD Clark, S Tuske, CJ Squire, K Das, D Sheng, ...
Journal of Biological Chemistry 278 (18), 16280-16288, 2003
1092003
TAS‐120 cancer target binding: defining reactivity and revealing the first fibroblast growth factor receptor 1 (FGFR1) irreversible structure
M Kalyukina, Y Yosaatmadja, MJ Middleditch, AV Patterson, JB Smaill, ...
ChemMedChem 14 (4), 494-500, 2019
1082019
Structure and function of GlmU from Mycobacterium tuberculosis
Z Zhang, EMM Bulloch, RD Bunker, EN Baker, CJ Squire
Acta Crystallographica Section D: Biological Crystallography 65 (3), 275-283, 2009
892009
MCR-1: a promising target for structure-based design of inhibitors to tackle polymyxin resistance
SJ Son, R Huang, CJ Squire, IKH Leung
Drug Discovery Today 24 (1), 206-216, 2019
802019
High-Resolution Crystal Structure of Plant Carboxylesterase AeCXE1, from Actinidia eriantha, and Its Complex with a High-Affinity Inhibitor Paraoxon,
NR Ileperuma, SDG Marshall, CJ Squire, HM Baker, JG Oakeshott, ...
Biochemistry 46 (7), 1851-1859, 2007
752007
In vitro studies with methylproamine: a potent new radioprotector
RF Martin, S Broadhurst, ME Reum, CJ Squire, GR Clark, ...
Cancer research 64 (3), 1067-1070, 2004
752004
Designer DNA-binding drugs: the crystal structure of a meta-hydroxy analogue of Hoechst 33258 bound to d (CGCGAATTCGCG) 2
GR Clark, CJ Squire, EJ Gray, W Leupin, S Neidle
Nucleic acids research 24 (24), 4882-4889, 1996
741996
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3
JU Flanagan, Y Yosaatmadja, RM Teague, MZL Chai, AP Turnbull, ...
Public Library of Science 7 (8), e43965, 2012
702012
Poxviral ankyrin proteins
MH Herbert, CJ Squire, AA Mercer
Viruses 7 (2), 709-738, 2015
672015
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system
G Bashiri, CJ Squire, EN Baker, NJ Moreland
Protein expression and purification 54 (1), 38-44, 2007
642007
Radiation damage and racemic protein crystallography reveal the unique structure of the GASA/snakin protein superfamily
H Yeung, CJ Squire, Y Yosaatmadja, S Panjikar, G López, A Molina, ...
Angewandte Chemie 128 (28), 8062-8065, 2016
632016
Defining the potassium binding region in an apple terpene synthase
S Green, CJ Squire, NJ Nieuwenhuizen, EN Baker, W Laing
Journal of Biological Chemistry 284 (13), 8661-8669, 2009
522009
Structure of Escherichia coli UDP-N-acetylmuramoyl: L-alanine ligase (MurC)
T Deva, EN Baker, CJ Squire, CA Smith
Acta Crystallographica Section D: Biological Crystallography 62 (12), 1466-1474, 2006
492006
Autocatalytically generated Thr-Gln ester bond cross-links stabilize the repetitive Ig-domain shaft of a bacterial cell surface adhesin
H Kwon, CJ Squire, PG Young, EN Baker
Proceedings of the National Academy of Sciences 111 (4), 1367-1372, 2014
482014
The high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkages
GR Clark, PD Pytel, CJ Squire
Nucleic acids research 40 (12), 5731-5738, 2012
442012
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Artículos 1–20