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Michael Weyand
Michael Weyand
Senior Staff Scientist, University of Bayreuth
Dirección de correo verificada de uni-bayreuth.de
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Structural insight into filament formation by mammalian septins
M Sirajuddin, M Farkasovsky, F Hauer, D Kühlmann, IG Macara, ...
Nature 449 (7160), 311-315, 2007
5372007
X-ray structure determination of a vanadium-dependent haloperoxidase from Ascophyllum nodosum at 2.0 Å resolution
M Weyand, HJ Hecht, M Kiess, MF Liaud, H Vilter, D Schomburg
Journal of molecular biology 293 (3), 595-611, 1999
3951999
Structural and mechanistic insights into the interaction between Rho and mammalian Dia
R Rose, M Weyand, M Lammers, T Ishizaki, MR Ahmadian, A Wittinghofer
Nature 435 (7041), 513-518, 2005
3412005
Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism
M Gertz, F Fischer, GTT Nguyen, M Lakshminarasimhan, M Schutkowski, ...
Proceedings of the National Academy of Sciences 110 (30), E2772-E2781, 2013
3382013
A common toxin fold mediates microbial attack and plant defense
C Ottmann, B Luberacki, I Küfner, W Koch, F Brunner, M Weyand, ...
Proceedings of the National Academy of Sciences 106 (25), 10359-10364, 2009
2852009
Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+-ATPase by combining X-ray crystallography and electron cryomicroscopy
C Ottmann, S Marco, N Jaspert, C Marcon, N Schauer, M Weyand, ...
Molecular cell 25 (3), 427-440, 2007
2842007
Phosphorylation‐independent interaction between 14‐3‐3 and exoenzyme S: from structure to pathogenesis
C Ottmann, L Yasmin, M Weyand, JL Veesenmeyer, MH Diaz, RH Palmer, ...
The EMBO journal 26 (3), 902-913, 2007
1972007
Structure of the Roc–COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase
K Gotthardt, M Weyand, A Kortholt, PJM Van Haastert, A Wittinghofer
The EMBO journal 27 (16), 2239-2249, 2008
1922008
The GTPase-activating protein Rap1GAP uses a catalytic asparagine
O Daumke, M Weyand, PP Chakrabarti, IR Vetter, A Wittinghofer
Nature 429 (6988), 197-201, 2004
1892004
Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate
S Kleinboelting, A Diaz, S Moniot, J van den Heuvel, M Weyand, LR Levin, ...
Proceedings of the National Academy of Sciences 111 (10), 3727-3732, 2014
1552014
Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling
M Molzan, B Schumacher, C Ottmann, A Baljuls, L Polzien, M Weyand, ...
Molecular and cellular biology 30 (19), 4698-4711, 2010
1432010
Structure of the p53 C-terminus bound to 14-3-3: implications for stabilization of the p53 tetramer
B Schumacher, J Mondry, P Thiel, M Weyand, C Ottmann
FEBS letters 584 (8), 1443-1448, 2010
1042010
A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A
C Ottmann, M Weyand, T Sassa, T Inoue, N Kato, A Wittinghofer, ...
Journal of molecular biology 386 (4), 913-919, 2009
1012009
Crystal structure of wild-type tryptophan synthase complexed with the natural substrate indole-3-glycerol phosphate
M Weyand, I Schlichting
Biochemistry 38 (50), 16469-16480, 1999
1001999
Structures, substrates, and regulators of mammalian Sirtuins–opportunities and challenges for drug development
S Moniot, M Weyand, C Steegborn
Frontiers in pharmacology 3, 16, 2012
932012
Synthesis and Characterization of Allosteric Probes of Substrate Channeling in the Tryptophan Synthase Bienzyme Complex,
H Ngo, R Harris, N Kimmich, P Casino, D Niks, L Blumenstein, ...
Biochemistry 46 (26), 7713-7727, 2007
732007
Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism
GTT Nguyen, S Schaefer, M Gertz, M Weyand, C Steegborn
Acta Crystallographica Section D: Biological Crystallography 69 (8), 1423-1432, 2013
722013
On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two …
V Kulik, E Hartmann, M Weyand, M Frey, A Gierl, D Niks, MF Dunn, ...
Journal of molecular biology 352 (3), 608-620, 2005
672005
On the role of αThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase
V Kulik, M Weyand, R Seidel, D Niks, D Arac, MF Dunn, I Schlichting
Journal of molecular biology 324 (4), 677-690, 2002
602002
Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase
M Weyand, I Schlichting, A Marabotti, A Mozzarelli
Journal of Biological Chemistry 277 (12), 10647-10652, 2002
502002
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20