Structural insight into filament formation by mammalian septins M Sirajuddin, M Farkasovsky, F Hauer, D Kühlmann, IG Macara, ... Nature 449 (7160), 311-315, 2007 | 537 | 2007 |
X-ray structure determination of a vanadium-dependent haloperoxidase from Ascophyllum nodosum at 2.0 Å resolution M Weyand, HJ Hecht, M Kiess, MF Liaud, H Vilter, D Schomburg Journal of molecular biology 293 (3), 595-611, 1999 | 395 | 1999 |
Structural and mechanistic insights into the interaction between Rho and mammalian Dia R Rose, M Weyand, M Lammers, T Ishizaki, MR Ahmadian, A Wittinghofer Nature 435 (7041), 513-518, 2005 | 341 | 2005 |
Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism M Gertz, F Fischer, GTT Nguyen, M Lakshminarasimhan, M Schutkowski, ... Proceedings of the National Academy of Sciences 110 (30), E2772-E2781, 2013 | 338 | 2013 |
A common toxin fold mediates microbial attack and plant defense C Ottmann, B Luberacki, I Küfner, W Koch, F Brunner, M Weyand, ... Proceedings of the National Academy of Sciences 106 (25), 10359-10364, 2009 | 285 | 2009 |
Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+-ATPase by combining X-ray crystallography and electron cryomicroscopy C Ottmann, S Marco, N Jaspert, C Marcon, N Schauer, M Weyand, ... Molecular cell 25 (3), 427-440, 2007 | 284 | 2007 |
Phosphorylation‐independent interaction between 14‐3‐3 and exoenzyme S: from structure to pathogenesis C Ottmann, L Yasmin, M Weyand, JL Veesenmeyer, MH Diaz, RH Palmer, ... The EMBO journal 26 (3), 902-913, 2007 | 197 | 2007 |
Structure of the Roc–COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase K Gotthardt, M Weyand, A Kortholt, PJM Van Haastert, A Wittinghofer The EMBO journal 27 (16), 2239-2249, 2008 | 192 | 2008 |
The GTPase-activating protein Rap1GAP uses a catalytic asparagine O Daumke, M Weyand, PP Chakrabarti, IR Vetter, A Wittinghofer Nature 429 (6988), 197-201, 2004 | 189 | 2004 |
Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate S Kleinboelting, A Diaz, S Moniot, J van den Heuvel, M Weyand, LR Levin, ... Proceedings of the National Academy of Sciences 111 (10), 3727-3732, 2014 | 155 | 2014 |
Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling M Molzan, B Schumacher, C Ottmann, A Baljuls, L Polzien, M Weyand, ... Molecular and cellular biology 30 (19), 4698-4711, 2010 | 143 | 2010 |
Structure of the p53 C-terminus bound to 14-3-3: implications for stabilization of the p53 tetramer B Schumacher, J Mondry, P Thiel, M Weyand, C Ottmann FEBS letters 584 (8), 1443-1448, 2010 | 104 | 2010 |
A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A C Ottmann, M Weyand, T Sassa, T Inoue, N Kato, A Wittinghofer, ... Journal of molecular biology 386 (4), 913-919, 2009 | 101 | 2009 |
Crystal structure of wild-type tryptophan synthase complexed with the natural substrate indole-3-glycerol phosphate M Weyand, I Schlichting Biochemistry 38 (50), 16469-16480, 1999 | 100 | 1999 |
Structures, substrates, and regulators of mammalian Sirtuins–opportunities and challenges for drug development S Moniot, M Weyand, C Steegborn Frontiers in pharmacology 3, 16, 2012 | 93 | 2012 |
Synthesis and Characterization of Allosteric Probes of Substrate Channeling in the Tryptophan Synthase Bienzyme Complex, H Ngo, R Harris, N Kimmich, P Casino, D Niks, L Blumenstein, ... Biochemistry 46 (26), 7713-7727, 2007 | 73 | 2007 |
Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism GTT Nguyen, S Schaefer, M Gertz, M Weyand, C Steegborn Acta Crystallographica Section D: Biological Crystallography 69 (8), 1423-1432, 2013 | 72 | 2013 |
On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two … V Kulik, E Hartmann, M Weyand, M Frey, A Gierl, D Niks, MF Dunn, ... Journal of molecular biology 352 (3), 608-620, 2005 | 67 | 2005 |
On the role of αThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase V Kulik, M Weyand, R Seidel, D Niks, D Arac, MF Dunn, I Schlichting Journal of molecular biology 324 (4), 677-690, 2002 | 60 | 2002 |
Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase M Weyand, I Schlichting, A Marabotti, A Mozzarelli Journal of Biological Chemistry 277 (12), 10647-10652, 2002 | 50 | 2002 |