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John E. Dick
John E. Dick
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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
D Bonnet, JE Dick
Nature medicine 3 (7), 730-737, 1997
96911997
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
T Lapidot, C Sirard, J Vormoor, B Murdoch, T Hoang, J Caceres-Cortes, ...
nature 367 (6464), 645-648, 1994
63761994
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
CA O’Brien, A Pollett, S Gallinger, JE Dick
Nature 445 (7123), 106-110, 2007
53042007
Cancer stem cells—perspectives on current status and future directions: AACR Workshop on cancer stem cells
MF Clarke, JE Dick, PB Dirks, CJ Eaves, CHM Jamieson, DL Jones, ...
Cancer research 66 (19), 9339-9344, 2006
40662006
Evolution of the cancer stem cell model
A Kreso, JE Dick
Cell stem cell 14 (3), 275-291, 2014
25822014
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
J Zhang, L Ding, L Holmfeldt, G Wu, SL Heatley, D Payne-Turner, ...
Nature 481 (7380), 157-163, 2012
18442012
Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
LI Shlush, S Zandi, A Mitchell, WC Chen, JM Brandwein, V Gupta, ...
Nature 506 (7488), 328-333, 2014
16742014
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
L Jin, KJ Hope, Q Zhai, F Smadja-Joffe, JE Dick
Nature medicine 12 (10), 1167-1174, 2006
15722006
Stem cell concepts renew cancer research
JE Dick
Blood, The Journal of the American Society of Hematology 112 (13), 4793-4807, 2008
14252008
Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry
DR Bandura, VI Baranov, OI Ornatsky, A Antonov, R Kinach, X Lou, ...
Analytical chemistry 81 (16), 6813-6822, 2009
13832009
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
KJ Hope, L Jin, JE Dick
Nature immunology 5 (7), 738-743, 2004
13322004
Hematopoiesis: a human perspective
S Doulatov, F Notta, E Laurenti, JE Dick
Cell stem cell 10 (2), 120-136, 2012
12202012
Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice
M Bhatia, JCY Wang, U Kapp, D Bonnet, JE Dick
Proceedings of the national academy of Sciences 94 (10), 5320-5325, 1997
12131997
Stem cell gene expression programs influence clinical outcome in human leukemia
K Eppert, K Takenaka, ER Lechman, L Waldron, B Nilsson, P Van Galen, ...
Nature medicine 17 (9), 1086-1093, 2011
12002011
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment
F Notta, S Doulatov, E Laurenti, A Poeppl, I Jurisica, JE Dick
Science 333 (6039), 218-221, 2011
11052011
Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy
A Larochelle, J Vormoor, H Hanenberg, JCY Wang, M Bhatia, T Lapidot, ...
Nature medicine 2 (12), 1329-1337, 1996
10081996
Cancer stem cells: lessons from leukemia
JCY Wang, JE Dick
Trends in cell biology 15 (9), 494-501, 2005
9132005
Distinct routes of lineage development reshape the human blood hierarchy across ontogeny
F Notta, S Zandi, N Takayama, S Dobson, OI Gan, G Wilson, ...
Science 351 (6269), aab2116, 2016
8992016
A newly discovered class of human hematopoietic cells with SCID-repopulating activity
M Bhatia, D Bonnet, B Murdoch, OI Gan, JE Dick
Nature medicine 4 (9), 1038-1045, 1998
8781998
Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer
A Kreso, CA O'Brien, P Van Galen, OI Gan, F Notta, AMK Brown, K Ng, ...
Science 339 (6119), 543-548, 2013
8742013
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