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Chris McKennan
Chris McKennan
Assistant Professor of Statistics, University of Pittsburgh
Dirección de correo verificada de pitt.edu
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Childhood asthma incidence, early and persistent wheeze, and neighborhood socioeconomic factors in the ECHO/CREW consortium
A Zanobetti, PH Ryan, B Coull, C Brokamp, S Datta, J Blossom, N Lothrop, ...
JAMA pediatrics 176 (8), 759-767, 2022
742022
Expression quantitative trait locus fine mapping of the 17q12–21 asthma locus in African American children: a genetic association and gene expression study
C Ober, CG McKennan, KM Magnaye, MC Altman, C Washington, ...
The Lancet Respiratory Medicine 8 (5), 482-492, 2020
622020
Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice
SH Min, A Suzuki, TJ Stalker, L Zhao, Y Wang, C McKennan, MJ Riese, ...
Nature communications 5 (1), 4691, 2014
552014
Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age
A Morin, CG McKennan, CET Pedersen, J Stokholm, BL Chawes, ...
Journal of Allergy and Clinical Immunology 146 (6), 1358-1366, 2020
512020
Induction of the immunoproteasome subunit Lmp7 links proteostasis and immunity in α-synuclein aggregation disorders
S Ugras, MJ Daniels, H Fazelinia, NS Gould, AK Yocum, KC Luk, E Luna, ...
EBioMedicine 31, 307-319, 2018
362018
Accounting for unobserved covariates with varying degrees of estimability in high-dimensional biological data
C McKennan, D Nicolae
Biometrika 106 (4), 823-840, 2019
322019
Unconjugated bilirubin is associated with protection from early-life wheeze and childhood asthma
KN Turi, C McKennan, T Gebretsadik, B Snyder, CM Seroogy, ...
Journal of Allergy and Clinical Immunology 148 (1), 128-138, 2021
262021
Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels
C McKennan, K Naughton, C Stanhope, M Kattan, GT O’Connor, ...
Epigenetics 16 (6), 662-676, 2021
252021
ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein
H Vais, M Wang, K Mallilankaraman, R Payne, C McKennan, JT Lock, ...
Elife 9, e53531, 2020
242020
Estimating and accounting for unobserved covariates in high-dimensional correlated data
C McKennan, D Nicolae
Journal of the American Statistical Association 117 (537), 225-236, 2022
222022
Robust and accurate estimation of cellular fraction from tissue omics data via ensemble deconvolution
M Cai, M Yue, T Chen, J Liu, E Forno, X Lu, T Billiar, J Celedón, ...
Bioinformatics 38 (11), 3004-3010, 2022
202022
Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB
AU Eliasen, CET Pedersen, MA Rasmussen, N Wang, M Soverini, A Fritz, ...
Journal of Allergy and Clinical Immunology 150 (3), 622-630, 2022
132022
Estimation and inference in metabolomics with non-random missing data and latent factors
C McKennan, C Ober, D Nicolae
The annals of applied statistics 14 (2), 789, 2020
132020
Environmental Influences on Child Health Outcomes-Children’s Respiratory Research Workgroup. Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in …
C Ober, CG McKennan, KM Magnaye, MC Altman, C Washington III, ...
Lancet Respir Med 8 (482-492), 10.1016, 2020
122020
A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome
A Morin, EE Thompson, BA Helling, LE Shorey-Kendrick, P Faber, ...
Journal of Allergy and Clinical Immunology 151 (6), 1609-1621, 2023
102023
Viral genetic determinants of prolonged respiratory syncytial virus infection among infants in a healthy term birth cohort
D Lawless, CG McKennan, SR Das, T Junier, ZM Xu, LJ Anderson, ...
The Journal of Infectious Diseases 227 (10), 1194-1202, 2023
92023
Factor analysis in high dimensional biological data with dependent observations
C McKennan
arXiv preprint arXiv:2009.11134, 2020
62020
African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans
C Washington III, M Dapas, A Biddanda, KM Magnaye, I Aneas, ...
Genome medicine 14 (1), 112, 2022
52022
Mid-Life Plasmalogens and Other Metabolites with Anti-Inflammatory Properties are Inversely Associated with Long term Cardiovascular Disease Events: Heart SCORE Study
A Saeed, C McKennan, J Duan, KE Kip, D Finegold, M Vu, J Swanson, ...
medRxiv, 2023.03. 02.23286731, 2023
42023
scMD facilitates cell type deconvolution using single-cell DNA methylation references
M Cai, J Zhou, C McKennan, J Wang
Communications Biology 7 (1), 1, 2024
32024
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