| Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity PW Burridge, YF Li, E Matsa, H Wu, SG Ong, A Sharma, A Holmström, ... Nature medicine 22 (5), 547-556, 2016 | 728 | 2016 |
| Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase ACY Chang, YX Fu, VC Garside, K Niessen, L Chang, M Fuller, A Setiadi, ... Developmental cell 21 (2), 288-300, 2011 | 187 | 2011 |
| Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development VC Garside, AC Chang, A Karsan, PA Hoodless Cellular and Molecular Life Sciences 70, 2899-2917, 2013 | 175 | 2013 |
| Humanizing the mdx mouse model of DMD: the long and the short of it N Yucel, AC Chang, JW Day, N Rosenthal, HM Blau NPJ Regenerative medicine 3 (1), 4, 2018 | 147 | 2018 |
| Differential regulation of transforming growth factor β signaling pathways by Notch in human endothelial cells YX Fu, A Chang, L Chang, K Niessen, S Eapen, A Setiadi, A Karsan Journal of Biological Chemistry 284 (29), 19452-19462, 2009 | 130 | 2009 |
| A human iPSC double-reporter system enables purification of cardiac lineage subpopulations with distinct function and drug response profiles JZ Zhang, V Termglinchan, NY Shao, I Itzhaki, C Liu, N Ma, L Tian, ... Cell Stem Cell 24 (5), 802-811. e5, 2019 | 125 | 2019 |
| Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients H Wu, H Yang, JW Rhee, JZ Zhang, CK Lam, K Sallam, ACY Chang, ... European heart journal 40 (45), 3685-3695, 2019 | 124 | 2019 |
| Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy ACY Chang, SG Ong, EL LaGory, PE Kraft, AJ Giaccia, JC Wu, HM Blau Proceedings of the National Academy of Sciences 113 (46), 13120-13125, 2016 | 75 | 2016 |
| Telomere shortening is a hallmark of genetic cardiomyopathies ACY Chang, ACH Chang, A Kirillova, K Sasagawa, W Su, G Weber, J Lin, ... Proceedings of the National Academy of Sciences 115 (37), 9276-9281, 2018 | 69 | 2018 |
| RUNX3 maintains the mesenchymal phenotype after termination of the Notch signal YX Fu, ACY Chang, M Fournier, L Chang, K Niessen, A Karsan Journal of Biological Chemistry 286 (13), 11803-11813, 2011 | 54 | 2011 |
| Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition VN Parikh, J Liu, C Shang, C Woods, AC Chang, M Zhao, DN Charo, ... American Journal of Physiology-Heart and Circulatory Physiology 315 (2 …, 2018 | 43 | 2018 |
| Silencing of MYH7 ameliorates disease phenotypes in human iPSC-cardiomyocytes A Dainis, K Zaleta-Rivera, A Ribeiro, ACH Chang, C Shang, F Lan, ... Physiological genomics 52 (7), 293-303, 2020 | 41 | 2020 |
| A highly specific CRISPR-Cas12j nuclease enables allele-specific genome editing Y Wang, T Qi, J Liu, Y Yang, Z Wang, Y Wang, T Wang, M Li, M Li, D Lu, ... Science Advances 9 (6), eabo6405, 2023 | 39 | 2023 |
| Probing the structure and function of an archaeal C/D-box methylation guide sRNA AD Omer, M Zago, A Chang, PP Dennis Rna 12 (9), 1708-1720, 2006 | 39 | 2006 |
| Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes ACY Chang, G Pardon, ACH Chang, H Wu, SG Ong, A Eguchi, S Ancel, ... Stem Cell Reports 16 (9), 2169-2181, 2021 | 35 | 2021 |
| A Notch‐dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion ACY Chang, VC Garside, M Fournier, J Smrz, P Vrljicak, P Umlandt, ... Developmental Dynamics 243 (7), 894-905, 2014 | 34 | 2014 |
| The Imbalance of p53–Park7 Signaling Axis Induces Iron Homeostasis Dysfunction in Doxorubicin‐Challenged Cardiomyocytes J Pan, W Xiong, A Zhang, H Zhang, H Lin, L Gao, J Ke, S Huang, J Zhang, ... Advanced Science 10 (15), 2206007, 2023 | 31 | 2023 |
| Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure P Cordero, VN Parikh, ET Chin, A Erbilgin, MJ Gloudemans, C Shang, ... Nature communications 10 (1), 2760, 2019 | 31 | 2019 |
| Hydrogen sulfide protects cardiomyocytes from doxorubicin-induced ferroptosis through the SLC7A11/GSH/GPx4 pathway by Keap1 S-sulfhydration and Nrf2 activation H Zhang, J Pan, S Huang, X Chen, ACY Chang, C Wang, J Zhang, ... Redox Biology 70, 103066, 2024 | 25 | 2024 |
| Notch activation augments nitric oxide/soluble guanylyl cyclase signaling in immortalized ovarian surface epithelial cells and ovarian cancer cells A El-Sehemy, AC Chang, AK Azad, N Gupta, Z Xu, H Steed, A Karsan, ... Cellular signalling 25 (12), 2780-2787, 2013 | 25 | 2013 |
Joseph C. WuStanford University, Director, Cardiovascular Institute, Professor of Medicine & Radiology,Dirección de correo verificada de stanford.edu
