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Samir Diab
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Process Design and Optimization for the Continuous Manufacturing of Nevirapine, an Active Pharmaceutical Ingredient for HIV Treatment
S Diab, DT McQuade, BF Gupton, DI Gerogiorgis
Organic Process Research & Development 23 (3), 320-333, 2019
392019
Process modeling, simulation, and technoeconomic evaluation of separation solvents for the continuous pharmaceutical manufacturing (CPM) of diphenhydramine
S Diab, DI Gerogiorgis
Organic Process Research & Development 21 (7), 924-946, 2017
382017
Process modelling, simulation and technoeconomic evaluation of crystallisation antisolvents for the continuous pharmaceutical manufacturing of rufinamide
S Diab, DI Gerogiorgis
Computers & Chemical Engineering 111, 102-114, 2018
342018
Dynamic modelling, simulation and economic evaluation of two CHO cell-based production modes towards developing biopharmaceutical manufacturing processes
H Shirahata, S Diab, H Sugiyama, DI Gerogiorgis
Chemical Engineering Research and Design 150, 218-233, 2019
302019
Design Space Identification and Visualization for Continuous Pharmaceutical Manufacturing
S Diab, DI Gerogiorgis
Pharmaceutics 12 (3), 235, 2020
192020
Technoeconomic Optimization of Continuous Crystallization for Three Active Pharmaceutical Ingredients: Cyclosporine, Paracetamol, and Aliskiren
S Diab, DI Gerogiorgis
Industrial & Engineering Chemistry Research 57 (29), 9489-9499, 2018
192018
Technoeconomic Mixed Integer Nonlinear Programming (MINLP) optimization for design of Liquid‐Liquid Extraction (LLE) cascades in continuous pharmaceutical manufacturing of atropine
S Diab, DI Gerogiorgis
AIChE Journal 65 (11), e16738, 2019
182019
Dynamic modelling and optimisation of the batch enzymatic synthesis of amoxicillin
AB Cuthbertson, AD Rodman, S Diab, DI Gerogiorgis
Processes 7 (6), 318, 2019
182019
Process modelling, design and technoeconomic Liquid–Liquid Extraction (LLE) optimisation for comparative evaluation of batch vs. continuous pharmaceutical manufacturing of atropine
S Diab, N Mytis, AG Boudouvis, DI Gerogiorgis
Computers & Chemical Engineering 124, 28-42, 2019
182019
Multiobjective Dynamic Optimization of Ampicillin Batch Crystallization: Sensitivity Analysis of Attainable Performance vs Product Quality Constraints
A Dafnomilis, S Diab, AD Rodman, AG Boudouvis, DI Gerogiorgis
Industrial & Engineering Chemistry Research 58 (40), 18756-18771, 2019
162019
Flow synthesis kinetics for lomustine, an anti-cancer active pharmaceutical ingredient
S Diab, M Raiyat, DI Gerogiorgis
Reaction Chemistry & Engineering 6 (10), 1819-1828, 2021
152021
Streamlining the development of an industrial dry granulation process for an immediate release tablet with systems modelling
G Bano, RM Dhenge, S Diab, DJ Goodwin, L Gorringe, M Ahmed, R Elkes, ...
Chemical Engineering Research and Design 178, 421-437, 2022
142022
Nonlinear optimization via explicit NRTL model solubility prediction for antisolvent mixture selection in artemisinin crystallization
HG Jolliffe, S Diab, DI Gerogiorgis
Organic Process Research & Development 22 (1), 40-53, 2018
142018
Technoeconomic evaluation of multiple mixed suspension-mixed product removal (MSMPR) crystallizer configurations for continuous cyclosporine crystallization
S Diab, DI Gerogiorgis
Organic Process Research & Development 21 (10), 1571-1587, 2017
142017
Mathematical Modeling and Optimization to Inform Impurity Control in an Industrial Active Pharmaceutical Ingredient Manufacturing Process
S Diab, C Christodoulou, G Taylor, P Rushworth
Organic Process Research & Development 26 (10), 2864–2881, 2022
122022
Application of a System Model for Continuous Manufacturing of an Active Pharmaceutical Ingredient in an Industrial Environment
S Diab, G Bano, C Christodoulou, N Hodnett, A Benedetti, M Andersson, ...
Journal of Pharmaceutical Innovation 17, 1333–1346, 2022
92022
No More Than Three: Technoeconomic Mixed Integer Nonlinear Programming Optimization of Mixed Suspension, Mixed Product Removal Crystallizer Cascades for Melitracen, an …
S Diab, DI Gerogiorgis
Industrial & Engineering Chemistry Research 59 (49), 21458-21475, 2020
92020
Process modelling, simulation and technoeconomic optimisation for continuous pharmaceutical manufacturing of (S)-warfarin
S Diab, DI Gerogiorgis
Computer Aided Chemical Engineering 43, 1643-1648, 2018
72018
Impact of Process Parameters and Formulation Properties on Dissolution Performance of an Extended Release Tablet: a Multivariate Analysis
S Diab, G Bano, RM Dhenge, J Taylor
Journal of Pharmaceutical Innovation 17, 892-910, 2021
52021
Techno-economic analysis of separation processes for continuous pharmaceutical manufacturing: Assessing process performance, material efficiency and economic viability
S Diab, DI Gerogiorgis
Chemistry Today 35 (2), 14-17, 2017
52017
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