Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity F Borges, F Roleira, N Milhazes, L Santana, E Uriarte Current medicinal chemistry 12 (8), 887-916, 2005 | 1261 | 2005 |
Chromone: a valid scaffold in medicinal chemistry A Gaspar, MJ Matos, J Garrido, E Uriarte, F Borges Chemical reviews 114 (9), 4960-4992, 2014 | 745 | 2014 |
Medicinal chemistry and bioinformatics-current trends in drugs discovery with networks topological indices H Gonzalez-Diaz, S Vilar, L Santana, E Uriarte Current topics in medicinal chemistry 7 (10), 1015-1029, 2007 | 382 | 2007 |
Recent advances on the role of topological indices in drug discovery research E Estrada, E Uriarte Current Medicinal Chemistry 8 (13), 1573-1588, 2001 | 358 | 2001 |
Hesperidin as a neuroprotective agent: a review of animal and clinical evidence M Hajialyani, M Hosein Farzaei, J Echeverría, SM Nabavi, E Uriarte, ... Molecules 24 (3), 648, 2019 | 325 | 2019 |
Proteomics, networks and connectivity indices H González‐Díaz, Y González‐Díaz, L Santana, FM Ubeira, E Uriarte Proteomics 8 (4), 750-778, 2008 | 310 | 2008 |
Coumarins—an important class of phytochemicals MJ Matos, L Santana, E Uriarte, OA Abreu, E Molina, EG Yordi Phytochemicals-isolation, characterisation and role in human health 25, 533-538, 2015 | 286 | 2015 |
Drug—drug interaction through molecular structure similarity analysis S Vilar, R Harpaz, E Uriarte, L Santana, R Rabadan, C Friedman Journal of the American Medical Informatics Association 19 (6), 1066-1074, 2012 | 263 | 2012 |
Antioxidant and pro-oxidant effects of polyphenolic compounds and structure-activity relationship evidence EG Yordi, EM Pérez, MJ Matos, EU Villares Nutrition, well-being and health 2, 23-48, 2012 | 260 | 2012 |
Effects of cis-resveratrol on inflammatory murine macrophages: antioxidant activity and down-regulation of inflammatory genes J Leiro, E Alvarez, JA Arranz, R Laguna, E Uriarte, F Orallo Journal of Leucocyte Biology 75 (6), 1156-1165, 2004 | 255 | 2004 |
Similarity-based modeling in large-scale prediction of drug-drug interactions S Vilar, E Uriarte, L Santana, T Lorberbaum, G Hripcsak, C Friedman, ... Nature protocols 9 (9), 2147-2163, 2014 | 252 | 2014 |
Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity L Santana, E Uriarte, F Roleira, N Milhazes, F Borges Current medicinal chemistry 11 (24), 3239-3261, 2004 | 235 | 2004 |
A novel approach for the virtual screening and rational design of anticancer compounds E Estrada, E Uriarte, A Montero, M Teijeira, L Santana, E De Clercq Journal of medicinal chemistry 43 (10), 1975-1985, 2000 | 224 | 2000 |
Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin–resveratrol hybrids S Vilar, E Quezada, L Santana, E Uriarte, M Yánez, N Fraiz, C Alcaide, ... Bioorganic & Medicinal Chemistry Letters 16 (2), 257-261, 2006 | 214 | 2006 |
A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins L Santana, E Uriarte, H González-Díaz, G Zagotto, R Soto-Otero, ... Journal of medicinal chemistry 49 (3), 1149-1156, 2006 | 192 | 2006 |
Potential pharmacological uses of chalcones: a patent review (from June 2011–2014) MJ Matos, S Vazquez-Rodriguez, E Uriarte, L Santana Expert opinion on therapeutic patents 25 (3), 351-366, 2015 | 183 | 2015 |
Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors MJ Matos, C Teran, Y Perez-Castillo, E Uriarte, L Santana, D Vina Journal of medicinal chemistry 54 (20), 7127-7137, 2011 | 177 | 2011 |
Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure–activity relationships A Chilin, R Battistutta, A Bortolato, G Cozza, S Zanatta, G Poletto, ... Journal of medicinal chemistry 51 (4), 752-759, 2008 | 171 | 2008 |
Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors A Gaspar, T Silva, M Yánez, D Vina, F Orallo, F Ortuso, E Uriarte, S Alcaro, ... Journal of medicinal chemistry 54 (14), 5165-5173, 2011 | 166 | 2011 |
A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors MJ Matos, D Viña, E Quezada, C Picciau, G Delogu, F Orallo, L Santana, ... Bioorganic & medicinal chemistry letters 19 (12), 3268-3270, 2009 | 162 | 2009 |