| Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium E Lloyd-Evans, AJ Morgan, X He, DA Smith, E Elliot-Smith, DJ Sillence, ... Nature medicine 14 (11), 1247-1255, 2008 | 962 | 2008 |
| NAADP mobilizes Ca2+ from reserve granules, lysosome-related organelles, in sea urchin eggs GC Churchill, Y Okada, JM Thomas, AA Genazzani, S Patel, A Galione Cell 111 (5), 703-708, 2002 | 571 | 2002 |
| Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells JM Cancela, GC Churchill, A Galione Nature 398 (6722), 74-76, 1999 | 465 | 1999 |
| Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP P Gomez-Suaga, B Luzon-Toro, D Churamani, L Zhang, D Bloor-Young, ... Human molecular genetics 21 (3), 511-525, 2012 | 370 | 2012 |
| Identification of a chemical probe for NAADP by virtual screening E Naylor, A Arredouani, SR Vasudevan, AM Lewis, R Parkesh, A Mizote, ... Nature chemical biology 5 (4), 220-226, 2009 | 358 | 2009 |
| A safe lithium mimetic for bipolar disorder N Singh, AC Halliday, JM Thomas, OV Kuznetsova, R Baldwin, ... Nature communications 4 (1), 1332, 2013 | 307 | 2013 |
| Purified TPC isoforms form NAADP receptors with distinct roles for Ca2+ signaling and endolysosomal trafficking M Ruas, K Rietdorf, A Arredouani, LC Davis, E Lloyd-Evans, H Koegel, ... Current biology 20 (8), 703-709, 2010 | 297 | 2010 |
| TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+ SJ Pitt, TM Funnell, M Sitsapesan, E Venturi, K Rietdorf, M Ruas, ... Journal of Biological Chemistry 285 (45), 35039-35046, 2010 | 259 | 2010 |
| Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and β cells M Yamasaki, R Masgrau, AJ Morgan, GC Churchill, S Patel, SJH Ashcroft, ... Journal of Biological Chemistry 279 (8), 7234-7240, 2004 | 251 | 2004 |
| The CRTC1-SIK1 pathway regulates entrainment of the circadian clock A Jagannath, R Butler, SIH Godinho, Y Couch, LA Brown, SR Vasudevan, ... Cell 154 (5), 1100-1111, 2013 | 244 | 2013 |
| Interactions between calcium release pathways: multiple messengers and multiple stores A Galione, GC Churchill Cell calcium 32 (5-6), 343-354, 2002 | 207 | 2002 |
| NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic β cells R Masgrau, GC Churchill, AJ Morgan, SJH Ashcroft, A Galione Current Biology 13 (3), 247-251, 2003 | 203 | 2003 |
| NAADP induces Ca2+ oscillations via a two‐pool mechanism by priming IP3‐and cADPR‐sensitive Ca2+ stores GC Churchill, A Galione The EMBO journal, 2001 | 199 | 2001 |
| Sperm deliver a new second messenger: NAADP GC Churchill, JS O'Neill, R Masgrau, S Patel, JM Thomas, AA Genazzani, ... Current biology 13 (2), 125-128, 2003 | 189 | 2003 |
| Coordination of Ca2+ signalling by NAADP S Patel, GC Churchill, A Galione Trends in biochemical sciences 26 (8), 482-489, 2001 | 188 | 2001 |
| Bidirectional Ca2+ signaling occurs between the endoplasmic reticulum and acidic organelles AJ Morgan, LC Davis, SKTY Wagner, AM Lewis, J Parrington, ... Journal of Cell Biology 200 (6), 789-805, 2013 | 176 | 2013 |
| Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells M Yamasaki, JM Thomas, GC Churchill, C Garnham, AM Lewis, ... Current biology 15 (9), 874-878, 2005 | 175 | 2005 |
| NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing LC Davis, AJ Morgan, JL Chen, CM Snead, D Bloor-Young, E Shenderov, ... Current Biology 22 (24), 2331-2337, 2012 | 161 | 2012 |
| Functionalized bis (thiosemicarbazonato) complexes of zinc and copper: synthetic platforms toward site-specific radiopharmaceuticals JP Holland, FI Aigbirhio, HM Betts, PD Bonnitcha, P Burke, M Christlieb, ... Inorganic chemistry 46 (2), 465-485, 2007 | 156 | 2007 |
| Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes GJS Pereira, H Hirata, GM Fimia, LG Do Carmo, C Bincoletto, SW Han, ... Journal of Biological Chemistry 286 (32), 27875-27881, 2011 | 148 | 2011 |
Antony GalioneUniversity of OxfordDirección de correo verificada de pharm.ox.ac.uk