A liquid-to-solid phase transition of the ALS protein FUS accelerated by disease mutation A Patel, HO Lee, L Jawerth, S Maharana, M Jahnel, MY Hein, S Stoynov, ... Cell 162 (5), 1066-1077, 2015 | 2702 | 2015 |
Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance SJ Pettitt, DB Krastev, I Brandsma, A Dréan, F Song, R Aleksandrov, ... Nature communications 9 (1), 1849, 2018 | 406 | 2018 |
Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex MN Nedelcheva, A Roguev, LB Dolapchiev, A Shevchenko, HB Taskov, ... Journal of molecular biology 347 (3), 509-521, 2005 | 166 | 2005 |
Protein dynamics in complex DNA lesions R Aleksandrov, A Dotchev, I Poser, D Krastev, G Georgiev, G Panova, ... Molecular cell 69 (6), 1046-1061. e5, 2018 | 154 | 2018 |
The chromatin response to double-strand DNA breaks and their repair R Aleksandrov, R Hristova, S Stoynov, A Gospodinov Cells 9 (8), 1853, 2020 | 75 | 2020 |
Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets DB Krastev, SJ Pettitt, J Campbell, F Song, BE Tanos, SS Stoynov, ... Nature communications 9 (1), 2016, 2018 | 30 | 2018 |
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends N Chappidi, T Quail, S Doll, LT Vogel, R Aleksandrov, S Felekyan, ... Cell 187 (4), 945-961. e18, 2024 | 25 | 2024 |
Stability of mRNA/DNA and DNA/DNA duplexes affects mRNA transcription RI Kraeva, DB Krastev, A Roguev, A Ivanova, MN Nedelcheva-Veleva, ... PLoS One 2 (3), e290, 2007 | 25 | 2007 |
Single-strand-specific DNase activity is an inherent property of the 140-kDa protein of the snake venom exonuclease SS Stoynov, AT Bakalova, SI Dimov, AV Mitkova, LB Dolapchiev FEBS letters 409 (2), 151-154, 1997 | 25 | 1997 |
Coordination of DNA synthesis and replicative unwinding by the S-phase checkpoint pathways MN Nedelcheva-Veleva, DB Krastev, SS Stoynov Nucleic acids research 34 (15), 4138-4146, 2006 | 22 | 2006 |
PARP1 roles in DNA repair and DNA replication: The basi (c) s of PARP inhibitor efficacy and resistance PB Kanev, A Atemin, S Stoynov, R Aleksandrov Seminars in Oncology 51 (1-2), 2-18, 2024 | 15 | 2024 |
The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence SD Uzunova, AS Zarkov, AM Ivanova, SS Stoynov, ... Cell division 9, 1-15, 2014 | 15 | 2014 |
Deregulated levels of RUVBL1 induce transcription-dependent replication stress RH Hristova, SS Stoynov, IR Tsaneva, AG Gospodinov The International Journal of Biochemistry & Cell Biology 128, 105839, 2020 | 10 | 2020 |
The thermodynamic patterns of eukaryotic genes suggest a mechanism for intron–exon recognition MN Nedelcheva-Veleva, M Sarov, I Yanakiev, E Mihailovska, MP Ivanov, ... Nature Communications 4 (1), 2101, 2013 | 10 | 2013 |
Novel fluorescent dyes for single DNA molecule techniques A Zarkov, A Vasilev, T Deligeorgiev, S Stoynov, M Nedelcheva-Veleva Molecular Imaging 12 (2), 7290.2012. 00018, 2013 | 10 | 2013 |
A unified mechanism for PARP inhibitor-induced PARP1 chromatin retention at DNA damage sites in living cells PB Kanev, S Varhoshkova, I Georgieva, M Lukarska, D Kirova, ... Cell Reports 43 (5), 2024 | 8 | 2024 |
DNArepairK: An interactive database for exploring the impact of anticancer drugs onto the dynamics of DNA repair proteins Y Babukov, R Aleksandrov, A Ivanova, A Atemin, S Stoynov Biomedicines 9 (9), 1238, 2021 | 8 | 2021 |
Mammalian INO80 chromatin remodeler cooperates with FANCM to mediate DNA interstrand crosslink-induced checkpoint activation and repair V Andreev, R Hristova, M Asparuhova, G Danovski, S Stoynov, ... DNA repair 74, 38-50, 2019 | 7 | 2019 |
CellTool: an open source software combining bio-image analysis and mathematical modeling G Danovski, T Dyankova, S Stoynov BioRxiv, 454256, 2018 | 7 | 2018 |
CellTool: An Open-Source Software Combining Bio-Image Analysis and Mathematical Modeling for the Study of DNA Repair Dynamics G Danovski, T Dyankova-Danovska, R Stamatov, R Aleksandrov, ... International Journal of Molecular Sciences 24 (23), 16784, 2023 | 6 | 2023 |