Microwave-assisted synthesis and structure–activity relationships of neuroactive pyrazolo [3, 4-b] pyrrolo [3, 4-d] pyridine derivatives NM Nascimento-Júnior, TCF Mendes, DM Leal, CMN Corrêa, RT Sudo, ... Bioorganic & medicinal chemistry letters 20 (1), 74-77, 2010 | 55 | 2010 |
Computational studies, design and synthesis of Pd (II)-based complexes: Allosteric inhibitors of the Human Topoisomerase-IIα FV Rocha, RL Farias, MA Lima, VS Batista, NM Nascimento-Junior, ... Journal of Inorganic Biochemistry 199, 110725, 2019 | 35 | 2019 |
Leishmaniose: Aspectos gerais relacionados com a doença, o ciclo do parasita, fármacos disponíveis, novos protótipos e vacinas VR Blanco, NM Nascimento-Júnior Revista Virtual de Química 9 (3), 861-876, 2017 | 32 | 2017 |
MAOS and medicinal chemistry: Some important examples from the last years NM Nascimento-Júnior, AE Kümmerle, EJ Barreiro, CAM Fraga Molecules 16 (11), 9274-9297, 2011 | 28 | 2011 |
A semiempirical study of acetylcholine hydrolysis catalyzed by Drosophila melanogaster acetylcholinesterase CMR Sant’Anna, A dos Santos Viana, NM do Nascimento Junior Bioorganic chemistry 34 (2), 77-89, 2006 | 25 | 2006 |
Sedation and antinociception induced by a new pyrazolo [3, 4-b] pyrrolo [3, 4-d] pyridine derivative (LASSBio-873) is modulated by activation of muscarinic receptors TCF Mendes, JM Raimundo, NM Nascimento-Junior, CAM Fraga, ... Pharmacology Biochemistry and Behavior 94 (1), 70-74, 2009 | 23 | 2009 |
Phthalimide Derivatives with Bioactivity against Plasmodium falciparum: Synthesis, Evaluation, and Computational Studies Involving bc1 Cytochrome Inhibition CY Okada-Junior, GC Monteiro, ACC Aguiar, VS Batista, JO De Souza, ... ACS omega 3 (8), 9424-9430, 2018 | 22 | 2018 |
In vitro and in silico assessment of antitumor properties and biomolecular binding studies for two new complexes based on NiII bearing k2N, S-donor ligands RL Farias, AMR Polez, DES Silva, RD Zanetti, MB Moreira, VS Batista, ... Materials Science and Engineering: C 121, 111815, 2021 | 19 | 2021 |
The emergence of the new P. 4 lineage of SARS-CoV-2 with spike L452R mutation in Brazil C Bittar, FS Possebon, LS Ullmann, DB Geraldini, VG da Costa, ... Frontiers in Public Health 9, 745310, 2021 | 14 | 2021 |
Alzheimer's disease: related targets, synthesis of available drugs, bioactive compounds under development and promising results obtained from multi-target approaches NFF Pirolla, VS Batista, FP Dias Viegas, VS Gontijo, CR McCarthy, ... Current Drug Targets 22 (5), 505-538, 2021 | 14 | 2021 |
Spirocyclic lactams and curvulinic acid derivatives from the endophytic fungus Curvularia lunata and their antibacterial and antifungal activities F Hilario, G Polinário, MR de Amorim, V de Sousa Batista, ... Fitoterapia 141, 104466, 2020 | 12 | 2020 |
Adoçantes artificiais e naturais: Propriedades químicas e biológicas, processos de produção e potenciais efeitos nocivos TR Ribeiro, NFF Pirolla, NM Nascimento-Júnior Revista Virtual de Química 12 (5), 1-41, 2020 | 11 | 2020 |
Antihyperalgesic effects of a novel muscarinic agonist (LASSB io‐873) in spinal nerve ligation in rats TCF Mendes, F Antunes, MM Trachez, NM Nascimento Jr, CAM Fraga, ... Clinical and Experimental Pharmacology and Physiology 40 (7), 404-411, 2013 | 10 | 2013 |
Construção, otimização e ancoragem molecular de substâncias bioativas em biomacromoléculas: um tutorial prático VS Batista, RL Farias, LPM Simões, NM Nascimento-Júnior Química Nova 45 (02), 223-234, 2022 | 7 | 2022 |
Leishmaniasis: general aspects related with the disease, the parasite cycle, available drugs, novel prototypes and vaccines VR Blanco, NM Nascimento-Junior Revista Virtual de Química, 861-876, 2017 | 6 | 2017 |
Synthesis and Anti-Mycobacterium tuberculosis Activity of Imidazo[2,1-b][1,3]oxazine Derivatives Against Multidrug-Resistant Strains GFDOSS FERNANDES, KF MANIERI, AF BONJORNO, DL CAMPOS, ... | 5 | 2023 |
Prevention and Reversal of MorphineInduced Tolerance by Novel Muscarinic Receptor Agonist in Rats with Neuropathic Pain CES Monteiro, N Nascimento-Júnior, M Trachez, R Tesch, T Mendes J Neurol Neurophysiol 6 (282), 2, 2015 | 5 | 2015 |
A new complex of silver (I) with probenecid: Synthesis, characterization, and studies of antibacterial and extended spectrum β-lactamases (ESBL) inhibition activities WR Lustri, SC Lazarini, NAS Aquaroni, FA Resende, NA Aleixo, ... Journal of Inorganic Biochemistry 243, 112201, 2023 | 4 | 2023 |
Computational Strategies Targeting Inhibition of Helicobacter pylori and Cryptococcus neoformans Ureases M Fabris, NM Nascimento-Júnior, MLF Bispo, PG Camargo Current Pharmaceutical Design 29 (10), 777-792, 2023 | 4 | 2023 |
Artificial and natural sweeteners: Chemical and biological properties, production processes and potential harmful effects TR Ribeiro, NFF Pirolla, NM Nascimento-Júnior Brazilian Chemical Soc, 2020 | 3 | 2020 |