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Toni-Kim Clarke
Toni-Kim Clarke
Forest Research
Dirección de correo verificada de forestresearch.gov.uk
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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
29762018
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ...
Nature neuroscience 22 (3), 343-352, 2019
23422019
Genome-wide association study identifies 30 loci associated with bipolar disorder
EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ...
Nature genetics 51 (5), 793-803, 2019
15912019
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ...
Cell 179 (7), 1469-1482. e11, 2019
12122019
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ...
Nature genetics 53 (6), 817-829, 2021
11362021
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ...
Cell 173 (7), 1705-1715. e16, 2018
7132018
Assessment of bidirectional relationships between physical activity and depression among adults: a 2-sample Mendelian randomization study
KW Choi, CY Chen, MB Stein, YC Klimentidis, MJ Wang, KC Koenen, ...
JAMA psychiatry 76 (4), 399-408, 2019
6772019
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
RK Walters, R Polimanti, EC Johnson, JN McClintick, MJ Adams, ...
Nature neuroscience 21 (12), 1656-1669, 2018
6642018
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
DM Howard, MJ Adams, M Shirali, TK Clarke, RE Marioni, G Davies, ...
Nature communications 9 (1), 1470, 2018
6262018
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N= 112 117)
TK Clarke, MJ Adams, G Davies, DM Howard, LS Hall, S Padmanabhan, ...
Molecular psychiatry 22 (10), 1376-1384, 2017
4352017
Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism
M Luciano, SP Hagenaars, G Davies, WD Hill, TK Clarke, M Shirali, ...
Nature genetics 50 (1), 6-11, 2018
3842018
Genome-wide association study meta-analysis of the alcohol use disorders identification test (AUDIT) in two population-based cohorts
S Sanchez-Roige, AA Palmer, P Fontanillas, SL Elson, ...
American Journal of Psychiatry 176 (2), 107-118, 2019
3782019
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits
H Zhou, JM Sealock, S Sanchez-Roige, TK Clarke, DF Levey, Z Cheng, ...
Nature neuroscience 23 (7), 809-818, 2020
3442020
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption
G Schumann, LJ Coin, A Lourdusamy, P Charoen, KH Berger, D Stacey, ...
Proceedings of the National Academy of Sciences 108 (17), 7119-7124, 2011
3352011
Minimal phenotyping yields genome-wide association signals of low specificity for major depression
N Cai, JA Revez, MJ Adams, TFM Andlauer, G Breen, EM Byrne, ...
Nature genetics 52 (4), 437-447, 2020
329*2020
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ...
Nature genetics 53 (9), 1311-1321, 2021
3192021
A large-scale genome-wide association study meta-analysis of cannabis use disorder
EC Johnson, D Demontis, TE Thorgeirsson, RK Walters, R Polimanti, ...
The Lancet Psychiatry 7 (12), 1032-1045, 2020
3042020
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
G Schumann, C Liu, P O’Reilly, H Gao, P Song, B Xu, B Ruggeri, N Amin, ...
Proceedings of the National Academy of Sciences 113 (50), 14372-14377, 2016
2662016
Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population
TK Clarke, MK Lupton, AM Fernandez-Pujals, J Starr, G Davies, S Cox, ...
Molecular psychiatry 21 (3), 419-425, 2016
2482016
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
SH Witt, F Streit, M Jungkunz, J Frank, S Awasthi, CS Reinbold, ...
Translational psychiatry 7 (6), e1155-e1155, 2017
2142017
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