| Cancer stem cells: a contentious hypothesis now moving forward ML O’Connor, D Xiang, S Shigdar, J Macdonald, Y Li, T Wang, C Pu, ... Cancer letters 344 (2), 180-187, 2014 | 291 | 2014 |
| RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule S Shigdar, J Lin, Y Yu, M Pastuovic, M Wei, W Duan Cancer science 102 (5), 991-998, 2011 | 269 | 2011 |
| Nucleic Acid Aptamer-Guided Cancer Therapeutics and Diagnostics: the Next Generation of Cancer Medicine WD Dongxi Xiang, Sarah Shigdar, Greg Qiao, Tao Wang, Abbas Z. Kouzani, Shu ... Theranostics 5 (1), 23-42, 2015 | 252 | 2015 |
| Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivo D Xiang, Y Zheng, W Duan, X Li, J Yin, S Shigdar, ML O’Connor, ... International journal of nanomedicine, 4103-4114, 2013 | 226 | 2013 |
| Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway J Ni, P Cozzi, J Hao, J Beretov, L Chang, W Duan, S Shigdar, W Delprado, ... The international journal of biochemistry & cell biology 45 (12), 2736-2748, 2013 | 207 | 2013 |
| RNA aptamers targeting cancer stem cell marker CD133 S Shigdar, L Qiao, SF Zhou, D Xiang, T Wang, Y Li, LY Lim, L Kong, L Li, ... Cancer letters 330 (1), 84-95, 2013 | 204 | 2013 |
| Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells L Li, D Xiang, S Shigdar, W Yang, Q Li, J Lin, K Liu, W Duan International journal of nanomedicine, 1083-1096, 2014 | 198 | 2014 |
| Cancer stem cell targeted therapy: progress amid controversies T Wang, S Shigdar, MP Gantier, Y Hou, L Wang, Y Li, H Al Shamaileh, ... Oncotarget 6 (42), 44191, 2015 | 175 | 2015 |
| Superior performance of aptamer in tumor penetration over antibody: implication of aptamer-based theranostics in solid tumors D Xiang, C Zheng, SF Zhou, S Qiao, PHL Tran, C Pu, Y Li, L Kong, ... Theranostics 5 (10), 1083, 2015 | 175 | 2015 |
| CD44 variant 6 is associated with prostate cancer metastasis and chemo‐/radioresistance J Ni, PJ Cozzi, JL Hao, J Beretov, L Chang, W Duan, S Shigdar, ... The Prostate 74 (6), 602-617, 2014 | 173 | 2014 |
| Aptamers as theranostic agents: modifications, serum stability and functionalisation S Shigdar, J Macdonald, M O'Connor, T Wang, D Xiang, H Al. Shamaileh, ... Sensors 13 (10), 13624-13637, 2013 | 153 | 2013 |
| Inflammation and cancer stem cells S Shigdar, Y Li, S Bhattacharya, M O’Connor, C Pu, J Lin, T Wang, ... Cancer letters 345 (2), 271-278, 2014 | 137 | 2014 |
| EpCAM aptamer-mediated survivin silencing sensitized cancer stem cells to doxorubicin in a breast cancer model T Wang, MP Gantier, D Xiang, AG Bean, M Bruce, SF Zhou, M Khasraw, ... Theranostics 5 (12), 1456, 2015 | 113 | 2015 |
| Challenges and opportunities for siRNA-based cancer treatment T Wang, S Shigdar, H Al Shamaileh, MP Gantier, W Yin, D Xiang, L Wang, ... Cancer letters 387, 77-83, 2017 | 110 | 2017 |
| Anything you can do, I can do better: Can aptamers replace antibodies in clinical diagnostic applications? M Bauer, M Strom, DS Hammond, S Shigdar Molecules 24 (23), 4377, 2019 | 108 | 2019 |
| Role of the EpCAM (CD326) in prostate cancer metastasis and progression J Ni, PJ Cozzi, W Duan, S Shigdar, PH Graham, KH John, Y Li Cancer and Metastasis Reviews 31, 779-791, 2012 | 95 | 2012 |
| Development of a bifunctional aptamer targeting the transferrin receptor and epithelial cell adhesion molecule (EpCAM) for the treatment of brain cancer metastases J Macdonald, J Henri, L Goodman, D Xiang, W Duan, S Shigdar ACS Chemical Neuroscience 8 (4), 777-784, 2017 | 94 | 2017 |
| Overcoming acquired drug resistance in colorectal cancer cells by targeted delivery of 5-FU with EGF grafted hollow mesoporous silica nanoparticles L Chen, X She, T Wang, L He, S Shigdar, W Duan, L Kong Nanoscale 7 (33), 14080-14092, 2015 | 88 | 2015 |
| Aptamers: Cutting edge of cancer therapies S Shigdar, B Schrand, PH Giangrande, V de Franciscis Molecular Therapy 29 (8), 2396-2411, 2021 | 85 | 2021 |
| Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery D Xiang, S Shigdar, AG Bean, M Bruce, W Yang, M Mathesh, T Wang, ... Theranostics 7 (17), 4071, 2017 | 82 | 2017 |