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Alexandre Ribeiro
Alexandre Ribeiro
Principal Analytical Scientist, Hovione, R&D
Dirección de correo verificada de hovione.com
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Año
Nuclear shape, mechanics, and mechanotransduction
KN Dahl, AJS Ribeiro, J Lammerding
Circulation research 102 (11), 1307-1318, 2008
8292008
Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness
AJS Ribeiro, YS Ang, JD Fu, RN Rivas, TMA Mohamed, GC Higgs, ...
Proceedings of the National Academy of Sciences 112 (41), 12705-12710, 2015
4992015
Disease model of GATA4 mutation reveals transcription factor cooperativity in human cardiogenesis
YS Ang, RN Rivas, AJS Ribeiro, R Srivas, J Rivera, NR Stone, K Pratt, ...
Cell 167 (7), 1734-1749. e22, 2016
2722016
3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration
H Wang, PC Brown, ECY Chow, L Ewart, SS Ferguson, S Fitzpatrick, ...
Clinical and translational science 14 (5), 1659-1680, 2021
1322021
Multi-imaging method to assay the contractile mechanical output of micropatterned human iPSC-derived cardiac myocytes
AJS Ribeiro, O Schwab, MA Mandegar, YS Ang, BR Conklin, D Srivastava, ...
Circulation research 120 (10), 1572-1583, 2017
1212017
Deformation‐based nuclear morphometry: Capturing nuclear shape variation in HeLa cells
GK Rohde, AJS Ribeiro, KN Dahl, RF Murphy
Cytometry Part A: The Journal of the International Society for Analytical …, 2008
1092008
For whom the cells pull: Hydrogel and micropost devices for measuring traction forces
AJS Ribeiro, AK Denisin, RE Wilson, BL Pruitt
Methods 94, 51-64, 2016
952016
Liver microphysiological systems for predicting and evaluating drug effects
AJS Ribeiro, X Yang, V Patel, R Madabushi, DG Strauss
Clinical Pharmacology & Therapeutics 106 (1), 139-147, 2019
942019
A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress
LM Judge, JA Perez-Bermejo, A Truong, AJS Ribeiro, JC Yoo, CL Jensen, ...
JCI insight 2 (14), 2017
882017
Time-dependent evolution of functional vs. remodeling signaling in induced pluripotent stem cell-derived cardiomyocytes and induced maturation with biomechanical stimulation
G Jung, G Fajardo, AJS Ribeiro, KB Kooiker, M Coronado, M Zhao, ...
The FASEB Journal 30 (4), 1464, 2015
812015
Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation
A Rubiano, A Indapurkar, R Yokosawa, A Miedzik, B Rosenzweig, ...
Clinical and translational science 14 (3), 1049-1061, 2021
712021
Spatial patterning of endothelium modulates cell morphology, adhesiveness and transcriptional signature
NF Huang, ES Lai, AJS Ribeiro, S Pan, BL Pruitt, GG Fuller, JP Cooke
Biomaterials 34 (12), 2928-2937, 2013
712013
Formation of composite polyacrylamide and silicone substrates for independent control of stiffness and strain
CS Simmons, AJS Ribeiro, BL Pruitt
Lab on a Chip 13 (4), 646-649, 2013
682013
IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making
X Chang, YM Tan, DG Allen, S Bell, PC Brown, L Browning, P Ceger, ...
Toxics 10 (5), 232, 2022
642022
Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and …
AJS Ribeiro, BD Guth, M Engwall, S Eldridge, CM Foley, L Guo, G Gintant, ...
Frontiers in Pharmacology 10, 934, 2019
512019
Perspectives on the evaluation and adoption of complex in vitro models in drug development: Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate)
SW Baran, PC Brown, AR Baudy, SC Fitzpatrick, C Frantz, A Fullerton, ...
ALTEX-Alternatives to animal experimentation 39 (2), 297-314, 2022
502022
Nuclear stiffening inhibits migration of invasive melanoma cells
AJS Ribeiro, P Khanna, A Sukumar, C Dong, KN Dahl
Cellular and molecular bioengineering 7, 544-551, 2014
462014
Controlling cell shape on hydrogels using lift-off protein patterning
J Moeller, AK Denisin, JY Sim, RE Wilson, AJS Ribeiro, BL Pruitt
PloS one 13 (1), e0189901, 2018
442018
Emerging technologies and their impact on regulatory science
E Anklam, MI Bahl, R Ball, RD Beger, J Cohen, S Fitzpatrick, P Girard, ...
Experimental Biology and Medicine 247 (1), 1-75, 2022
432022
Silencing of MYH7 ameliorates disease phenotypes in human iPSC-cardiomyocytes
A Dainis, K Zaleta-Rivera, A Ribeiro, ACH Chang, C Shang, F Lan, ...
Physiological genomics 52 (7), 293-303, 2020
412020
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Artículos 1–20