A distinctive role for focal adhesion proteins in three-dimensional cell motility SI Fraley, Y Feng, R Krishnamurthy, DH Kim, A Celedon, GD Longmore, ... Nature cell biology 12 (6), 598-604, 2010 | 742 | 2010 |
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation CCL Wong, DM Gilkes, H Zhang, J Chen, H Wei, P Chaturvedi, SI Fraley, ... Proceedings of the National Academy of Sciences 108 (39), 16369-16374, 2011 | 530 | 2011 |
Emerging technologies for molecular diagnosis of sepsis M Sinha, J Jupe, H Mack, TP Coleman, SM Lawrence, SI Fraley Clinical microbiology reviews 31 (2), 10.1128/cmr. 00089-17, 2018 | 337 | 2018 |
Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions SI Fraley, P Wu, L He, Y Feng, R Krisnamurthy, GD Longmore, D Wirtz Scientific reports 5 (1), 14580, 2015 | 266 | 2015 |
A global transcriptional network connecting noncoding mutations to changes in tumor gene expression W Zhang, A Bojorquez-Gomez, DO Velez, G Xu, KS Sanchez, JP Shen, ... Nature genetics 50 (4), 613-620, 2018 | 149 | 2018 |
3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry DO Velez, B Tsui, T Goshia, CL Chute, A Han, H Carter, SI Fraley Nature communications 8 (1), 1651, 2017 | 133 | 2017 |
Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners SI Fraley, Y Feng, A Giri, GD Longmore, D Wirtz Nature communications 3 (1), 719, 2012 | 125 | 2012 |
A spatial model of YAP/TAZ signaling reveals how stiffness, dimensionality, and shape contribute to emergent outcomes KE Scott, SI Fraley, P Rangamani Proceedings of the National Academy of Sciences 118 (20), e2021571118, 2021 | 107 | 2021 |
Trainable high resolution melt curve machine learning classifier for large-scale reliable genotyping of sequence variants P Athamanolap, V Parekh, SI Fraley, V Agarwal, DJ Shin, MA Jacobs, ... PloS one 9 (10), e109094, 2014 | 66 | 2014 |
Cell adhesiveness serves as a biophysical marker for metastatic potential P Beri, A Popravko, B Yeoman, A Kumar, K Chen, E Hodzic, A Chiang, ... Cancer research 80 (4), 901-911, 2020 | 61 | 2020 |
Universal digital high-resolution melt: a novel approach to broad-based profiling of heterogeneous biological samples SI Fraley, J Hardick, B Jo Masek, P Athamanolap, RE Rothman, ... Nucleic acids research 41 (18), e175-e175, 2013 | 54 | 2013 |
Macromolecular crowding tunes 3D collagen architecture and cell morphogenesis SK Ranamukhaarachchi, RN Modi, A Han, DO Velez, A Kumar, AJ Engler, ... Biomaterials science 7 (2), 618-633, 2019 | 53 | 2019 |
Nested machine learning facilitates increased sequence content for large-scale automated high resolution melt genotyping SI Fraley, P Athamanolap, BJ Masek, J Hardick, KC Carroll, YH Hsieh, ... Scientific reports 6 (1), 19218, 2016 | 52 | 2016 |
3D collagen architecture regulates cell adhesion through degradability, thereby controlling metabolic and oxidative stress DO Velez, SK Ranamukhaarachchi, A Kumar, RN Modi, EW Lim, ... Integrative Biology 11 (5), 221-234, 2019 | 49 | 2019 |
Massively parallel digital high resolution melt for rapid and absolutely quantitative sequence profiling DO Velez, H Mack, J Jupe, S Hawker, N Kulkarni, B Hedayatnia, Y Zhang, ... Scientific Reports 7 (1), 42326, 2017 | 49 | 2017 |
Interpretation of cancer mutations using a multiscale map of protein systems F Zheng, MR Kelly, DJ Ramms, ML Heintschel, K Tao, B Tutuncuoglu, ... Science 374 (6563), eabf3067, 2021 | 48 | 2021 |
NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells KL Yap, SI Fraley, MM Thiaville, N Jinawath, K Nakayama, J Wang, ... Cancer research 72 (16), 4085-4096, 2012 | 43 | 2012 |
Emerging themes and unifying concepts underlying cell behavior regulation by the pericellular space KE Scott, K Rychel, S Ranamukhaarachchi, P Rangamani, SI Fraley Acta biomaterialia 96, 81-98, 2019 | 24 | 2019 |
Can rubrics combat gender bias in faculty hiring? M Blair-Loy, OV Mayorova, PC Cosman, SI Fraley Science 377 (6601), 35-37, 2022 | 23 | 2022 |
An update on current and novel molecular diagnostics for the diagnosis of invasive fungal infections JD Jenks, PL White, SE Kidd, T Goshia, SI Fraley, M Hoenigl, ... Expert Review of Molecular Diagnostics 23 (12), 1135-1152, 2023 | 20 | 2023 |