| Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines SJ Kattman, AD Witty, M Gagliardi, NC Dubois, M Niapour, A Hotta, J Ellis, ... Cell stem cell 8 (2), 228-240, 2011 | 1392 | 2011 |
| Correction of sickle cell disease in transgenic mouse models by gene therapy R Pawliuk, KA Westerman, ME Fabry, E Payen, R Tighe, EE Bouhassira, ... Science 294 (5550), 2368-2371, 2001 | 745 | 2001 |
| A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells M Vedadi, D Barsyte-Lovejoy, F Liu, S Rival-Gervier, A Allali-Hassani, ... Nature chemical biology 7 (8), 566-74, 2011 | 567 | 2011 |
| Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein AP Wong, CE Bear, S Chin, P Pasceri, TO Thompson, LJ Huan, F Ratjen, ... Nature biotechnology 30 (9), 876-82, 2012 | 478 | 2012 |
| Silencing and variegation of gammaretrovirus and lentivirus vectors J Ellis Human gene therapy 16 (11), 1241-1246, 2005 | 467 | 2005 |
| Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency A Hotta, AYL Cheung, N Farra, K Vijayaragavan, CA Séguin, JS Draper, ... Nature methods 6 (5), 370-376, 2009 | 379 | 2009 |
| MBNL proteins repress ES-cell-specific alternative splicing and reprogramming H Han, M Irimia, PJ Ross, HK Sung, B Alipanahi, L David, A Golipour, ... Nature 498 (7453), 241-5, 2013 | 355 | 2013 |
| Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation AYL Cheung, LM Horvath, D Grafodatskaya, P Pasceri, R Weksberg, ... Human molecular genetics 20 (11), 2103-2115, 2011 | 309 | 2011 |
| A dominant chromatin‐opening activity in 5′ hypersensitive site 3 of the human beta‐globin locus control region. J Ellis, KC Tan‐Un, A Harper, D Michalovich, N Yannoutsos, S Philipsen, ... The EMBO journal 15 (3), 562-568, 1996 | 300 | 1996 |
| A vertebrate Polycomb response element governs segmentation of the posterior hindbrain A Sing, D Pannell, A Karaiskakis, K Sturgeon, M Djabali, J Ellis, ... Cell 138 (5), 885-897, 2009 | 294 | 2009 |
| Silencing of gene expression: implications for design of retrovirus vectors D Pannell, J Ellis Reviews in medical virology 11 (4), 205-217, 2001 | 233 | 2001 |
| Retroviral vector silencing during iPS cell induction: an epigenetic beacon that signals distinct pluripotent states A Hotta, J Ellis Journal of cellular biochemistry 105 (4), 940-948, 2008 | 222 | 2008 |
| Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres E Fussner, M Strauss, U Djuric, R Li, K Ahmed, M Hart, J Ellis, ... European Molecular Biology Organization reports 13 (11), 92-6, 2012 | 211 | 2012 |
| Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code D Pannell, CS Osborne, S Yao, T Sukonnik, P Pasceri, A Karaiskakis, ... The EMBO journal, 2000 | 200 | 2000 |
| SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons K Zaslavsky, WB Zhang, FP McCready, DC Rodrigues, E Deneault, C Loo, ... Nature neuroscience 22 (4), 556-564, 2019 | 177 | 2019 |
| Constitutive heterochromatin reorganization during somatic cell reprogramming E Fussner, U Djuric, M Strauss, A Hotta, C Perez‐Iratxeta, F Lanner, ... The EMBO journal 30 (9), 1778-1789, 2011 | 175 | 2011 |
| Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications S Yao, T Sukonnik, T Kean, RR Bharadwaj, P Pasceri, J Ellis Molecular Therapy 10 (1), 27-36, 2004 | 162 | 2004 |
| Synthetic human beta‐globin 5′ HS2 constructs function as locus control regions only in multicopy transgene concatamers. J Ellis, D Talbot, N Dillon, F Grosveld The EMBO journal 12 (1), 127-134, 1993 | 153 | 1993 |
| High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors F Moreau-Gaudry, P Xia, G Jiang, NP Perelman, G Bauer, J Ellis, ... Blood, The Journal of the American Society of Hematology 98 (9), 2664-2672, 2001 | 143 | 2001 |
| Complete disruption of autism-susceptibility genes by gene editing predominantly reduces functional connectivity of isogenic human neurons E Deneault, SH White, DC Rodrigues, PJ Ross, M Faheem, K Zaslavsky, ... Stem cell reports 11 (5), 1211-1225, 2018 | 129 | 2018 |
