Cancer regression in patients after transfer of genetically engineered lymphocytes RA Morgan, ME Dudley, JR Wunderlich, MS Hughes, JC Yang, ... Science 314 (5796), 126-129, 2006 | 4228 | 2006 |
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2 RA Morgan, JC Yang, M Kitano, ME Dudley, CM Laurencot, ... Molecular therapy 18 (4), 843-851, 2010 | 2981 | 2010 |
T lymphocyte-directed gene therapy for ADA− SCID: initial trial results after 4 years RM Blaese, KW Culver, AD Miller, CS Carter, T Fleisher, M Clerici, ... Science 270 (5235), 475-480, 1995 | 2264 | 1995 |
Adoptive cell transfer: a clinical path to effective cancer immunotherapy SA Rosenberg, NP Restifo, JC Yang, RA Morgan, ME Dudley Nature Reviews Cancer 8 (4), 299-308, 2008 | 2167 | 2008 |
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1 PF Robbins, RA Morgan, SA Feldman, JC Yang, RM Sherry, ME Dudley, ... Journal of Clinical Oncology 29 (7), 917-924, 2011 | 1974 | 2011 |
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems NJ Caplen, S Parrish, F Imani, A Fire, RA Morgan Proceedings of the National Academy of Sciences 98 (17), 9742-9747, 2001 | 1929 | 2001 |
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells JN Kochenderfer, ME Dudley, SA Feldman, WH Wilson, DE Spaner, ... Blood, The Journal of the American Society of Hematology 119 (12), 2709-2720, 2012 | 1849 | 2012 |
Gene transfer into humans—immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction SA Rosenberg, P Aebersold, K Cornetta, A Kasid, RA Morgan, R Moen, ... New England journal of medicine 323 (9), 570-578, 1990 | 1799 | 1990 |
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen LA Johnson, RA Morgan, ME Dudley, L Cassard, JC Yang, MS Hughes, ... Blood, The Journal of the American Society of Hematology 114 (3), 535-546, 2009 | 1771 | 2009 |
Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19 JN Kochenderfer, WH Wilson, JE Janik, ME Dudley, M Stetler-Stevenson, ... Blood, The Journal of the American Society of Hematology 116 (20), 4099-4102, 2010 | 1681 | 2010 |
Anti-BCMA CAR T-cell therapy bb2121 in relapsed or refractory multiple myeloma N Raje, J Berdeja, YI Lin, D Siegel, S Jagannath, D Madduri, M Liedtke, ... New England Journal of Medicine 380 (18), 1726-1737, 2019 | 1600 | 2019 |
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy RA Morgan, N Chinnasamy, D Abate-Daga, A Gros, PF Robbins, Z Zheng, ... Journal of immunotherapy 36 (2), 133-151, 2013 | 1337 | 2013 |
T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis MR Parkhurst, JC Yang, RC Langan, ME Dudley, DAN Nathan, ... Molecular Therapy 19 (3), 620-626, 2011 | 1232 | 2011 |
Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation B Ensoli, L Buonaguro, G Barillari, V Fiorelli, R Gendelman, RA Morgan, ... Journal of virology 67 (1), 277-287, 1993 | 983 | 1993 |
A pilot trial using lymphocytes genetically engineered with an NY-ESO-1–reactive T-cell receptor: long-term follow-up and correlates with response PF Robbins, SH Kassim, TLN Tran, JS Crystal, RA Morgan, SA Feldman, ... Clinical Cancer Research 21 (5), 1019-1027, 2015 | 918 | 2015 |
Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia W Haso, DW Lee, NN Shah, M Stetler-Stevenson, CM Yuan, IH Pastan, ... Blood, The Journal of the American Society of Hematology 121 (7), 1165-1174, 2013 | 708 | 2013 |
Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability CJ Cohen, Y Zhao, Z Zheng, SA Rosenberg, RA Morgan Cancer research 66 (17), 8878-8886, 2006 | 607 | 2006 |
Construction and preclinical evaluation of an anti-CD19 chimeric antigen receptor JN Kochenderfer, SA Feldman, Y Zhao, H Xu, MA Black, RA Morgan, ... Journal of immunotherapy 32 (7), 689-702, 2009 | 571 | 2009 |
dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference NJ Caplen, J Fleenor, A Fire, RA Morgan Gene 252 (1-2), 95-105, 2000 | 462 | 2000 |
Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond CJ Cohen, YF Li, M El-Gamil, PF Robbins, SA Rosenberg, RA Morgan Cancer research 67 (8), 3898-3903, 2007 | 450 | 2007 |