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Richard Morgan
Richard Morgan
CSO Be Biopharma
Dirección de correo verificada de be.bio
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Cancer regression in patients after transfer of genetically engineered lymphocytes
RA Morgan, ME Dudley, JR Wunderlich, MS Hughes, JC Yang, ...
Science 314 (5796), 126-129, 2006
42282006
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
RA Morgan, JC Yang, M Kitano, ME Dudley, CM Laurencot, ...
Molecular therapy 18 (4), 843-851, 2010
29812010
T lymphocyte-directed gene therapy for ADA− SCID: initial trial results after 4 years
RM Blaese, KW Culver, AD Miller, CS Carter, T Fleisher, M Clerici, ...
Science 270 (5235), 475-480, 1995
22641995
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
SA Rosenberg, NP Restifo, JC Yang, RA Morgan, ME Dudley
Nature Reviews Cancer 8 (4), 299-308, 2008
21672008
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
PF Robbins, RA Morgan, SA Feldman, JC Yang, RM Sherry, ME Dudley, ...
Journal of Clinical Oncology 29 (7), 917-924, 2011
19742011
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
NJ Caplen, S Parrish, F Imani, A Fire, RA Morgan
Proceedings of the National Academy of Sciences 98 (17), 9742-9747, 2001
19292001
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
JN Kochenderfer, ME Dudley, SA Feldman, WH Wilson, DE Spaner, ...
Blood, The Journal of the American Society of Hematology 119 (12), 2709-2720, 2012
18492012
Gene transfer into humans—immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction
SA Rosenberg, P Aebersold, K Cornetta, A Kasid, RA Morgan, R Moen, ...
New England journal of medicine 323 (9), 570-578, 1990
17991990
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
LA Johnson, RA Morgan, ME Dudley, L Cassard, JC Yang, MS Hughes, ...
Blood, The Journal of the American Society of Hematology 114 (3), 535-546, 2009
17712009
Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
JN Kochenderfer, WH Wilson, JE Janik, ME Dudley, M Stetler-Stevenson, ...
Blood, The Journal of the American Society of Hematology 116 (20), 4099-4102, 2010
16812010
Anti-BCMA CAR T-cell therapy bb2121 in relapsed or refractory multiple myeloma
N Raje, J Berdeja, YI Lin, D Siegel, S Jagannath, D Madduri, M Liedtke, ...
New England Journal of Medicine 380 (18), 1726-1737, 2019
16002019
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
RA Morgan, N Chinnasamy, D Abate-Daga, A Gros, PF Robbins, Z Zheng, ...
Journal of immunotherapy 36 (2), 133-151, 2013
13372013
T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
MR Parkhurst, JC Yang, RC Langan, ME Dudley, DAN Nathan, ...
Molecular Therapy 19 (3), 620-626, 2011
12322011
Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation
B Ensoli, L Buonaguro, G Barillari, V Fiorelli, R Gendelman, RA Morgan, ...
Journal of virology 67 (1), 277-287, 1993
9831993
A pilot trial using lymphocytes genetically engineered with an NY-ESO-1–reactive T-cell receptor: long-term follow-up and correlates with response
PF Robbins, SH Kassim, TLN Tran, JS Crystal, RA Morgan, SA Feldman, ...
Clinical Cancer Research 21 (5), 1019-1027, 2015
9182015
Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia
W Haso, DW Lee, NN Shah, M Stetler-Stevenson, CM Yuan, IH Pastan, ...
Blood, The Journal of the American Society of Hematology 121 (7), 1165-1174, 2013
7082013
Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability
CJ Cohen, Y Zhao, Z Zheng, SA Rosenberg, RA Morgan
Cancer research 66 (17), 8878-8886, 2006
6072006
Construction and preclinical evaluation of an anti-CD19 chimeric antigen receptor
JN Kochenderfer, SA Feldman, Y Zhao, H Xu, MA Black, RA Morgan, ...
Journal of immunotherapy 32 (7), 689-702, 2009
5712009
dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference
NJ Caplen, J Fleenor, A Fire, RA Morgan
Gene 252 (1-2), 95-105, 2000
4622000
Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond
CJ Cohen, YF Li, M El-Gamil, PF Robbins, SA Rosenberg, RA Morgan
Cancer research 67 (8), 3898-3903, 2007
4502007
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