| ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy Y Shi, K Yamada, SA Liddelow, ST Smith, L Zhao, W Luo, RM Tsai, ... Nature 549 (7673), 523-527, 2017 | 1070 | 2017 |
| TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques Y Wang, TK Ulland, JD Ulrich, W Song, JA Tzaferis, JT Hole, P Yuan, ... Journal of Experimental Medicine 213 (5), 667-675, 2016 | 802 | 2016 |
| Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight Y Shi, DM Holtzman Nature Reviews Immunology 18 (12), 759-772, 2018 | 552 | 2018 |
| Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model Y Shi, M Manis, J Long, K Wang, PM Sullivan, J Remolina Serrano, ... Journal of Experimental Medicine 216 (11), 2546-2561, 2019 | 344 | 2019 |
| Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation TM Achariyar, B Li, W Peng, PB Verghese, Y Shi, E McConnell, ... Molecular neurodegeneration 11, 1-20, 2016 | 250 | 2016 |
| Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia C Wang, M Xiong, M Gratuze, X Bao, Y Shi, PS Andhey, M Manis, ... Neuron 109 (10), 1657-1674. e7, 2021 | 228 | 2021 |
| Cholesterol and matrisome pathways dysregulated in astrocytes and microglia TCW Julia, L Qian, NH Pipalia, MJ Chao, SA Liang, Y Shi, BR Jain, ... Cell 185 (13), 2213-2233. e25, 2022 | 200 | 2022 |
| 25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner MY Wong, M Lewis, JJ Doherty, Y Shi, AG Cashikar, A Amelianchik, ... Journal of neuroinflammation 17, 1-17, 2020 | 85 | 2020 |
| Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms Y Shi, PS Andhey, C Ising, K Wang, LL Snipes, K Boyer, S Lawson, ... Neuron 109 (15), 2413-2426. e7, 2021 | 84 | 2021 |
| Apolipoprotein E4 reduction with antisense oligonucleotides decreases neurodegeneration in a tauopathy model A Litvinchuk, TPV Huynh, Y Shi, RJ Jackson, MB Finn, M Manis, ... Annals of neurology 89 (5), 952-966, 2021 | 57 | 2021 |
| An in vitro assay to study induction of the regenerative state in sensory neurons E Frey, V Valakh, S Karney-Grobe, Y Shi, J Milbrandt, A DiAntonio Experimental neurology 263, 350-363, 2015 | 49 | 2015 |
| Cholesterol and matrisome pathways dysregulated in human APOE∊ 4 Glia J TCW, SA Liang, L Qian, NH Pipalia, MJ Chao, Y Shi, SE Bertelsen, ... Available at SSRN 3435267, 2019 | 43* | 2019 |
| Elevation of brain magnesium potentiates neural stem cell proliferation in the hippocampus of young and aged mice S Jia, Y Liu, Y Shi, Y Ma, Y Hu, M Wang, X Li Journal of cellular physiology 231 (9), 1903-1912, 2016 | 30 | 2016 |
David HoltzmanWashington University in St. LouisDirección de correo verificada de neuro.wustl.edu
