Structure and activation of C1, the complex initiating the classical pathway of the complement cascade SA Mortensen, B Sander, RK Jensen, JS Pedersen, MM Golas, ... Proceedings of the National Academy of Sciences 114 (5), 986-991, 2017 | 123 | 2017 |
Structural immunology of complement receptors 3 and 4 T Vorup-Jensen, RK Jensen Frontiers in immunology 9, 2716, 2018 | 122 | 2018 |
Functional and structural insight into properdin control of complement alternative pathway amplification DV Pedersen, L Roumenina, RK Jensen, TAF Gadeberg, C Marinozzi, ... The EMBO Journal 36 (8), 1084-1099, 2017 | 70 | 2017 |
Structural basis for properdin oligomerization and convertase stimulation in the human complement system DV Pedersen, TAF Gadeberg, C Thomas, Y Wang, N Joram, RK Jensen, ... Frontiers in Immunology 10, 2007, 2019 | 60 | 2019 |
Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction F Jabs, M Plum, NS Laursen, RK Jensen, B Mølgaard, M Miehe, ... Nature Communications 9 (1), 7, 2018 | 53 | 2018 |
The structure of the RAGE: S100A6 complex reveals a unique mode of homodimerization for S100 proteins L Yatime, C Betzer, RK Jensen, S Mortensen, PH Jensen, GR Andersen Structure 24 (12), 2043-2052, 2016 | 50 | 2016 |
A potent complement factor C3–specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement RK Jensen, R Pihl, TAF Gadeberg, JK Jensen, KR Andersen, S Thiel, ... Journal of Biological Chemistry 293 (17), 6269-6281, 2018 | 41 | 2018 |
ITIH4 acts as a protease inhibitor by a novel inhibitory mechanism R Pihl, RK Jensen, EC Poulsen, L Jensen, AG Hansen, IB Thøgersen, ... Science advances 7 (2), eaba7381, 2021 | 35 | 2021 |
Complement receptor 3 forms a compact high-affinity complex with iC3b RK Jensen, G Bajic, M Sen, TA Springer, T Vorup-Jensen, GR Andersen The Journal of Immunology 206 (12), 3032-3042, 2021 | 32 | 2021 |
Structure of intact IgE and the mechanism of ligelizumab revealed by electron microscopy RK Jensen, F Jabs, M Miehe, B Mølgaard, W Pfützner, C Möbs, E Spillner, ... Allergy 75 (8), 1956-1965, 2020 | 28 | 2020 |
Structure of the omalizumab Fab RK Jensen, M Plum, L Tjerrild, T Jakob, E Spillner, GR Andersen Acta Crystallographica Section F: Structural Biology Communications 71 (4 …, 2015 | 23 | 2015 |
Well-based crystallization of lipidic cubic phase microcrystals for serial X-ray crystallography experiments R Andersson, C Safari, P Båth, R Bosman, A Shilova, P Dahl, S Ghosh, ... Acta Crystallographica Section D: Structural Biology 75 (10), 937-946, 2019 | 20 | 2019 |
A C3-specific nanobody that blocks all three activation pathways in the human and murine complement system H Pedersen, RK Jensen, AG Hansen, TAF Gadeberg, S Thiel, ... Journal of Biological Chemistry 295 (26), 8746-8758, 2020 | 19 | 2020 |
Complement activation by human IgG antibodies to galactose‐α‐1,3‐galactose JM Bernth Jensen, NS Laursen, RK Jensen, GR Andersen, JC Jensenius, ... Immunology 161 (1), 66-79, 2020 | 15 | 2020 |
A complement C3–specific nanobody for modulation of the alternative cascade identifies the C-terminal domain of C3b as functional in C5 convertase activity H Pedersen, RK Jensen, JMB Jensen, R Fox, DV Pedersen, HG Olesen, ... The Journal of Immunology 205 (8), 2287-2300, 2020 | 13 | 2020 |
Structural immunology of complement receptors 3 and 4. Front Immunol 9: 2716 T Vorup-Jensen, RK Jensen | 9 | 2018 |
Models of the complement C1 complex SA Mortensen, B Sander, RK Jensen, JS Pedersen, MM Golas, S Thiel, ... Proceedings of the National Academy of Sciences 115 (17), E3866-E3866, 2018 | 7 | 2018 |
Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αMβ2 RK Jensen, H Pedersen, J Lorentzen, NS Laursen, T Vorup-Jensen, ... Journal of Biological Chemistry 298 (8), 2022 | 6 | 2022 |
ColabSeg: An interactive tool for editing, processing, and visualizing membrane segmentations from cryo-ET data M Siggel, RK Jensen, VJ Maurer, J Mahamid, J Kosinski Journal of Structural Biology 216 (2), 108067, 2024 | 4 | 2024 |
Structure-guided engineering of a complement component C3-binding nanobody improves specificity and adds cofactor activity H Pedersen, RK Jensen, AG Hansen, SV Petersen, S Thiel, NS Laursen, ... Frontiers in immunology 13, 872536, 2022 | 4 | 2022 |