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Xia Yang
Xia Yang
Professor, Integrative Biology and Physiology, Molecular and Medical Pharmacology, UCLA
Dirección de correo verificada de ucla.edu - Página principal
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An integrative genomics approach to infer causal associations between gene expression and disease
EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ...
Nature genetics 37 (7), 710-717, 2005
12442005
Mapping the genetic architecture of gene expression in human liver
EE Schadt, C Molony, E Chudin, K Hao, X Yang, PY Lum, A Kasarskis, ...
PLoS biology 6 (5), e107, 2008
12042008
Variations in DNA elucidate molecular networks that cause disease
Y Chen, J Zhu, PY Lum, X Yang, S Pinto, DJ MacNeil, C Zhang, J Lamb, ...
Nature 452 (7186), 429-435, 2008
10802008
Tissue-specific expression and regulation of sexually dimorphic genes in mice
X Yang, EE Schadt, S Wang, H Wang, AP Arnold, L Ingram-Drake, ...
Genome research 16 (8), 995-1004, 2006
9542006
Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk
T Bhattacharyya, SJ Nicholls, EJ Topol, R Zhang, X Yang, D Schmitt, X Fu, ...
Jama 299 (11), 1265-1276, 2008
6722008
Co-regulatory networks of human serum proteins link genetics to disease
V Emilsson, M Ilkov, JR Lamb, N Finkel, EF Gudmundsson, R Pitts, ...
Science 361 (6404), 769-773, 2018
5052018
Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity
AS Dimas, V Lagou, A Barker, JW Knowles, R Mägi, MF Hivert, A Benazzo, ...
Diabetes 63 (6), 2158-2171, 2014
3962014
Dosage compensation is less effective in birds than in mammals
Y Itoh, E Melamed, X Yang, K Kampf, S Wang, N Yehya, A Van Nas, ...
Journal of biology 6, 1-15, 2007
3802007
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks
X Yang, JL Deignan, H Qi, J Zhu, S Qian, J Zhong, G Torosyan, S Majid, ...
Nature genetics 41 (4), 415-423, 2009
3282009
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver
X Yang, B Zhang, C Molony, E Chudin, K Hao, J Zhu, A Gaedigk, C Suver, ...
Genome research 20 (8), 1020-1036, 2010
3272010
Extended multiplexing of tandem mass tags (TMT) labeling reveals age and high fat diet specific proteome changes in mouse epididymal adipose tissue
DL Plubell, PA Wilmarth, Y Zhao, AM Fenton, J Minnier, AP Reddy, ...
Molecular & Cellular Proteomics 16 (5), 873-890, 2017
3052017
Integrating pathway analysis and genetics of gene expression for genome-wide association studies
H Zhong, X Yang, LM Kaplan, C Molony, EE Schadt
The American Journal of Human Genetics 86 (4), 581-591, 2010
2922010
Sherlock: detecting gene-disease associations by matching patterns of expression QTL and GWAS
X He, CK Fuller, Y Song, Q Meng, B Zhang, X Yang, H Li
The American Journal of Human Genetics 92 (5), 667-680, 2013
2712013
Targeting BCAA catabolism to treat obesity-associated insulin resistance
M Zhou, J Shao, CY Wu, L Shu, W Dong, Y Liu, M Chen, RM Wynn, ...
Diabetes 68 (9), 1730-1746, 2019
2672019
Applications and limitations of mouse models for understanding human atherosclerosis
M Von Scheidt, Y Zhao, Z Kurt, C Pan, L Zeng, X Yang, H Schunkert, ...
Cell metabolism 25 (2), 248-261, 2017
2322017
Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease
VP Mäkinen, M Civelek, Q Meng, B Zhang, J Zhu, C Levian, T Huan, ...
PLoS genetics 10 (7), e1004502, 2014
232*2014
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes
H Zhong, J Beaulaurier, PY Lum, C Molony, X Yang, DJ MacNeil, ...
PLoS genetics 6 (5), e1000932, 2010
2062010
Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases
M Narayanan, JL Huynh, K Wang, X Yang, S Yoo, J McElwee, B Zhang, ...
Molecular systems biology 10 (7), 743, 2014
1832014
A systems biology framework identifies molecular underpinnings of coronary heart disease
T Huan, B Zhang, Z Wang, R Joehanes, J Zhu, AD Johnson, S Ying, ...
Arteriosclerosis, thrombosis, and vascular biology 33 (6), 1427-1434, 2013
178*2013
Single cell molecular alterations reveal target cells and pathways of concussive brain injury
D Arneson, G Zhang, Z Ying, Y Zhuang, HR Byun, IS Ahn, ...
Nature communications 9 (1), 3894, 2018
1582018
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Artículos 1–20