| Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease Z Wang, E Klipfell, BJ Bennett, R Koeth, BS Levison, B DuGar, ... Nature 472 (7341), 57-63, 2011 | 5813 | 2011 |
| Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis RA Koeth, Z Wang, BS Levison, JA Buffa, E Org, BT Sheehy, EB Britt, X Fu, ... Nature medicine 19 (5), 576-585, 2013 | 4749 | 2013 |
| Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk WHW Tang, Z Wang, BS Levison, RA Koeth, EB Britt, X Fu, Y Wu, ... New England Journal of Medicine 368 (17), 1575-1584, 2013 | 3519 | 2013 |
| Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang, L Li, X Fu, Y Wu, ... Cell 165 (1), 111-124, 2016 | 1831 | 2016 |
| Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease WHW Tang, Z Wang, DJ Kennedy, Y Wu, JA Buffa, B Agatisa-Boyle, XS Li, ... Circulation research 116 (3), 448-455, 2015 | 1159 | 2015 |
| Prognostic value of elevated levels of intestinal microbe-generated metabolite trimethylamine-N-oxide in patients with heart failure: refining the gut hypothesis WHW Tang, Z Wang, Y Fan, B Levison, JE Hazen, LM Donahue, Y Wu, ... Journal of the American College of Cardiology 64 (18), 1908-1914, 2014 | 739 | 2014 |
| Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide Z Wang, WHW Tang, JA Buffa, X Fu, EB Britt, RA Koeth, BS Levison, ... European heart journal 35 (14), 904-910, 2014 | 625 | 2014 |
| γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO RA Koeth, BS Levison, MK Culley, JA Buffa, Z Wang, JC Gregory, E Org, ... Cell metabolism 20 (5), 799-812, 2014 | 561 | 2014 |
| Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors XS Li, S Obeid, R Klingenberg, B Gencer, F Mach, L Räber, S Windecker, ... European heart journal 38 (11), 814-824, 2017 | 488 | 2017 |
| An abundant dysfunctional apolipoprotein A1 in human atheroma Y Huang, JA DiDonato, BS Levison, D Schmitt, L Li, Y Wu, J Buffa, T Kim, ... Nature medicine 20 (2), 193-203, 2014 | 413 | 2014 |
| Choline Diet and Its Gut Microbe–Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload–Induced Heart Failure CL Organ, H Otsuka, S Bhushan, Z Wang, J Bradley, R Trivedi, ... Circulation: Heart Failure 9 (1), e002314, 2016 | 369 | 2016 |
| Intestinal microbiota-dependent phosphatidylcholine metabolites, diastolic dysfunction, and adverse clinical outcomes in chronic systolic heart failure WHW Tang, Z Wang, K Shrestha, AG Borowski, Y Wu, RW Troughton, ... Journal of cardiac failure 21 (2), 91-96, 2015 | 364 | 2015 |
| Paradoxical Association of Enhanced Cholesterol Efflux With Increased Incident Cardiovascular RisksSignificance XM Li, WHW Tang, MK Mosior, Y Huang, Y Wu, W Matter, V Gao, ... Arteriosclerosis, thrombosis, and vascular biology 33 (7), 1696-1705, 2013 | 343 | 2013 |
| Intestinal Microbiota‐Generated Metabolite Trimethylamine‐N‐Oxide and 5‐Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of Intestinal Microbiota in … V Senthong, Z Wang, XS Li, Y Fan, Y Wu, WHW Tang, SL Hazen Journal of the American Heart Association 5 (6), e002816, 2016 | 287 | 2016 |
| Plasma trimethylamine N-oxide, a gut microbe–generated phosphatidylcholine metabolite, is associated with atherosclerotic burden V Senthong, XS Li, T Hudec, J Coughlin, Y Wu, B Levison, Z Wang, ... Journal of the American College of Cardiology 67 (22), 2620-2628, 2016 | 257 | 2016 |
| Increased trimethylamine N-oxide portends high mortality risk independent of glycemic control in patients with type 2 diabetes mellitus WHW Tang, Z Wang, XS Li, Y Fan, DS Li, Y Wu, SL Hazen Clinical chemistry 63 (1), 297-306, 2017 | 230 | 2017 |
| Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk WHW Tang, J Hartiala, Y Fan, Y Wu, AFR Stewart, J Erdmann, ... Arteriosclerosis, thrombosis, and vascular biology 32 (11), 2803-2812, 2012 | 202 | 2012 |
| Prognostic role of serum chloride levels in acute decompensated heart failure JL Grodin, J Simon, R Hachamovitch, Y Wu, G Jackson, M Halkar, ... Journal of the American College of Cardiology 66 (6), 659-666, 2015 | 187 | 2015 |
| Trimethylamine N‐Oxide and Mortality Risk in Patients With Peripheral Artery Disease V Senthong, Z Wang, Y Fan, Y Wu, SL Hazen, WHW Tang Journal of the American Heart Association 5 (10), e004237, 2016 | 177 | 2016 |
| Prognostic role of pulmonary arterial capacitance in advanced heart failure M Dupont, W Mullens, HN Skouri, Z Abrahams, Y Wu, DO Taylor, ... Circulation: Heart Failure 5 (6), 778-785, 2012 | 153 | 2012 |