| Interleukin-10-deficient mice develop chronic enterocolitis R Kühn, J Löhler, D Rennick, K Rajewsky, W Müller Cell 75 (2), 263-274, 1993 | 5391 | 1993 |
| Inducible gene targeting in mice R Kühn, F Schwenk, M Aguet, K Rajewsky Science 269 (5229), 1427-1429, 1995 | 2343 | 1995 |
| AB cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene D Kitamura, J Roes, R Kühn, K Rajewsky Nature 350 (6317), 423-426, 1991 | 2210 | 1991 |
| Generation and analysis of interleukin-4 deficient mice R Kühn, K Rajewsky, W Müller Science 254 (5032), 707-710, 1991 | 1587 | 1991 |
| Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells VT Chu, T Weber, B Wefers, W Wurst, S Sander, K Rajewsky, R Kühn Nature biotechnology 33 (5), 543-548, 2015 | 1477 | 2015 |
| Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4 (+) TH1-like responses. DJ Berg, N Davidson, R Kühn, W Müller, S Menon, G Holland, ... The Journal of clinical investigation 98 (4), 1010-1020, 1996 | 1456 | 1996 |
| In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death KP Lam, R Kühn, K Rajewsky Cell 90 (6), 1073-1083, 1997 | 1455 | 1997 |
| In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction … RT Gazzinelli, M Wysocka, S Hieny, T Scharton-Kersten, A Cheever, ... Journal of immunology (Baltimore, Md.: 1950) 157 (2), 798-805, 1996 | 1177 | 1996 |
| Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function M Piwecka, P Glažar, LR Hernandez-Miranda, S Memczak, SA Wolf, ... Science 357 (6357), eaam8526, 2017 | 1118 | 2017 |
| Requirement of mammalian DNA polymerase-β in base-excision repair RW Sobol, JK Horton, R Kühn, H Gu, RK Singhal, R Prasad, K Rajewsky, ... Nature 379 (6561), 183-186, 1996 | 1116 | 1996 |
| BACE knockout mice are healthy despite lacking the primary β-secretase activity in brain: implications for Alzheimer’s disease therapeutics SL Roberds, J Anderson, G Basi, MJ Bienkowski, DG Branstetter, ... Human molecular genetics 10 (12), 1317-1324, 2001 | 998 | 2001 |
| Essential role for TrkB receptors in hippocampus-mediated learning L Minichiello, M Korte, D Wolfer, R Kühn, K Unsicker, V Cestari, ... Neuron 24 (2), 401-414, 1999 | 995 | 1999 |
| Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity M Rios, G Fan, C Fekete, J Kelly, B Bates, R Kuehn, RM Lechan, ... Molecular endocrinology 15 (10), 1748-1757, 2001 | 973 | 2001 |
| Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. DJ Berg, R Kühn, K Rajewsky, W Müller, S Menon, N Davidson, G Grünig, ... The Journal of clinical investigation 96 (5), 2339-2347, 1995 | 698 | 1995 |
| MHC class I expression in mice lacking the proteasome subunit LMP-7 HJ Fehling, W Swat, C Laplace, R Kühn, K Rajewsky, U Müller, ... Science 265 (5176), 1234-1237, 1994 | 655 | 1994 |
| Conditional gene targeting. K Rajewsky, H Gu, R Kühn, UA Betz, W Müller, J Roes, F Schwenk The Journal of clinical investigation 98 (3), 600-603, 1996 | 629 | 1996 |
| Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress MB Müller, S Zimmermann, I Sillaber, TP Hagemeyer, JM Deussing, ... Nature neuroscience 6 (10), 1100-1107, 2003 | 556 | 2003 |
| T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice. NJ Davidson, MW Leach, MM Fort, L Thompson-Snipes, R Kühn, ... The Journal of experimental medicine 184 (1), 241-251, 1996 | 492 | 1996 |
| Inducible gene deletion in astroglia and radial glia—a valuable tool for functional and lineage analysis T Mori, K Tanaka, A Buffo, W Wurst, R Kühn, M Götz Glia 54 (1), 21-34, 2006 | 461 | 2006 |
| DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals G Fan, C Beard, RZ Chen, G Csankovszki, Y Sun, M Siniaia, ... Journal of Neuroscience 21 (3), 788-797, 2001 | 430 | 2001 |
